CHEMBL4283606
Ligand Summary
Name: N-(3,4-dimethoxyphenethyl)-2-(methylthio)-4-morpholinopyrimidine-5-carboxamide
PubChem: 142592652
ChEMBL: CHEMBL4283606
LyCHI: 5XVH211P56H5
Target Activities
PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
2 Activities
PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.55 | Eur J Med Chem, (2018) 145:None:673 | ||||
PDE11A
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.18 | Eur J Med Chem, (2018) 145:None:673 | ||||
PDE4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.87 | Eur J Med Chem, (2018) 145:None:673 | ||||
PDE4C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.49 | Eur J Med Chem, (2018) 145:None:673 | ||||