CHEMBL1940403
Ligand Summary
Name: 4-(4-chlorophenyl)-1-(3-(4-fluorophenylthio)propyl)piperidin-4-ol
PubChem: 21533446
ChEMBL: CHEMBL1940403
LyCHI: 5RJ14YQBJHAN
Target Activities
DRD2
D(2) dopamine receptor
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Kd | 8.71 | J Med Chem, (2019) 62:21:9488 | ||||
Ki | 8.68 | J Med Chem, (2019) 62:21:9488 | ||||
Ki | 8.28 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
Ki | 8.06 | Bioorg. Med. Chem., (2012) 20:3:1291 | ||||
HTR2A
5-hydroxytryptamine receptor 2A
2 Activities
DRD3
D(3) dopamine receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 7.31 | Bioorg. Med. Chem., (2012) 20:3:1291 | ||||
SLC6A4
Sodium-dependent serotonin transporter
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 6.8 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
HTR1A
5-hydroxytryptamine receptor 1A
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 7.13 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 6.3 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
DRD1
D(1A) dopamine receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 7.57 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||