Pharos : Ligand Details - 4XWLPHDFK892

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: PQR620

PubChem: 121334520

Guide to Pharmacology: 10142

ChEMBL: CHEMBL4286698

LyCHI: 4XWLPHDFK892

Target Activities

Explore Associated and Predicted Targets

MTOR

Tclin

Serine/threonine-protein kinase mTOR

6 Activities

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1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	9.57			30359003

Ki	7.97			30359003

Kd	9.57		J Med Chem, (2018) 61:22:10084	30359003

Kd	9.57		J Med Chem, (2019) 62:18:8609	31465220

Ki	7.97		J Med Chem, (2018) 61:22:10084	30359003

Ki	7.97		J Med Chem, (2019) 62:18:8609	31465220

PIK3CA

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	5.38			30359003

Kd	6			30359003

PIK3C3

Tchem

Phosphatidylinositol 3-kinase catalytic subunit type 3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	5.56			30359003