CHEMBL1683075
Ligand Summary
Name: ((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)methanone
PubChem: 53322810
ChEMBL: CHEMBL1683075
LyCHI: 4TCBNCA34U8K
Target Activities
CCR2
C-C chemokine receptor type 2
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.07 | Bioorg. Med. Chem. Lett., (2011) 21:9:2626 | ||||
IC50 | 8.05 | Bioorg. Med. Chem. Lett., (2011) 21:5:1442 | ||||
IC50 | 7.96 | Bioorg. Med. Chem. Lett., (2011) 21:5:1442 | ||||
IC50 | 7.77 | Bioorg. Med. Chem. Lett., (2011) 21:5:1442 | ||||
IC50 | 7.74 | Bioorg. Med. Chem. Lett., (2011) 21:9:2626 | ||||
CCR5
C-C chemokine receptor type 5
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | Bioorg. Med. Chem. Lett., (2011) 21:5:1442 | ||||
KCNH2
Potassium voltage-gated channel subfamily H member 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.31 | Bioorg. Med. Chem. Lett., (2011) 21:9:2626 | ||||