CHEMBL206815
Ligand Summary
Name: (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat
PubChem: 11452716
Guide to Pharmacology: 6482
ChEMBL: CHEMBL206815
LyCHI: 4CA4SN4F8P52
Target Activities
Items per page:
10
1 – 7 of 7
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.36 | Bioorg. Med. Chem., (2009) 17:2:444 | ||||
IC50 | 7.7 | Bioorg. Med. Chem. Lett., (2006) 16:6:1605 | ||||
IC50 | 8.3 | None, (2016) None:None:None | ||||
IC50 | 8.3 | None, (2016) None:None:None | ||||
IC50 | 7.7 | |||||
MMP1
Interstitial collagenase
4 Activities
ADAM9
Disintegrin and metalloproteinase domain-containing protein 9
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.07 | None, (2016) None:None:None | ||||
IC50 | 7.07 | None, (2016) None:None:None | ||||
MMP3
Stromelysin-1
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8 | None, (2016) None:None:None | ||||
IC50 | 8 | None, (2016) None:None:None | ||||
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.15 | None, (2016) None:None:None | ||||
IC50 | 7.15 | None, (2016) None:None:None | ||||
MMP9
Matrix metalloproteinase-9
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.09 | None, (2016) None:None:None | ||||
IC50 | 7.09 | None, (2016) None:None:None | ||||