Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

ADAM17

Tchem

Disintegrin and metalloproteinase domain-containing protein 17

10 Activities

Items per page:

1 – 10 of 10

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.7		16426848

IC50	8.4	Bioorg Med Chem Lett, (2017) 27:8:1848	28274635

IC50	8.3	None, (2016) None:None:None

IC50	8.3	None, (2016) None:None:None

IC50	7.7	Bioorg. Med. Chem. Lett., (2006) 16:6:1605	16426848

IC50	6.92	Bioorg Med Chem Lett, (2017) 27:8:1848	28274635

IC50	6.9	Bioorg Med Chem Lett, (2017) 27:8:1848	28274635

IC50	6.85	Bioorg. Med. Chem. Lett., (2006) 16:6:1605	16426848

IC50	6.8	Bioorg Med Chem Lett, (2017) 27:8:1848	28274635

IC50	6.36	Bioorg. Med. Chem., (2009) 17:2:444	19095454

MMP1

Tchem

Interstitial collagenase

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.48		16426848

IC50	7.48	Bioorg. Med. Chem. Lett., (2006) 16:6:1605	16426848

IC50	6.84	None, (2016) None:None:None

IC50	6.84	None, (2016) None:None:None

MMP13

Tchem

Collagenase 3

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.1		16426848

IC50	8.1	Bioorg. Med. Chem. Lett., (2006) 16:6:1605	16426848

MMP3

Tchem

Stromelysin-1

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference
IC50	8	None, (2016) None:None:None

IC50	8	None, (2016) None:None:None

MMP9

Tchem

Matrix metalloproteinase-9

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference
IC50	7.09	None, (2016) None:None:None

IC50	7.09	None, (2016) None:None:None

ADAM10

Tchem

Disintegrin and metalloproteinase domain-containing protein 10

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference
IC50	7.15	None, (2016) None:None:None

IC50	7.15	None, (2016) None:None:None

ADAM9

Tchem

Disintegrin and metalloproteinase domain-containing protein 9

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference
IC50	7.07	None, (2016) None:None:None

IC50	7.07	None, (2016) None:None:None