Pharos : Ligand Details - 4BTDZRWX2SR3

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: NI-57

PubChem: 91827373

Guide to Pharmacology: 8573

ChEMBL: CHEMBL3752151

LyCHI: 4BTDZRWX2SR3

Target Activities

Explore Associated and Predicted Targets

BRPF1

Tchem

Peregrin

9 Activities

Items per page:

1 – 9 of 9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.51

IC50	8.51		J Med Chem, (2017) 60:16:6998	28714688

Kd	7.51		MedChemComm, (2015) 6:9:1587

Kd	7.51		J. Med. Chem., (2016) 59:4:1271	26572217

Kd	7.51		J Med Chem, (2017) 60:16:6998	28714688

Kd	7.51		MedChemComm, (2016) 7:12:2246

IC50	7.33		Journal of Medicinal Chemistry, (2017) None:16:6998	28714688

IC50	7.16		J Med Chem, (2017) 60:16:6998	28714688

IC50	6.94		J Med Chem, (2017) 60:16:6998	28714688

BRPF3

Tchem

Bromodomain and PHD finger-containing protein 3

8 Activities

Items per page:

1 – 8 of 8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.39

IC50	6.85		J Med Chem, (2017) 60:16:6998	28714688

Kd	6.39		MedChemComm, (2015) 6:9:1587

Kd	6.39		J. Med. Chem., (2016) 59:4:1271	26572217

Kd	6.39		J Med Chem, (2017) 60:16:6998	28714688

Kd	6.39		MedChemComm, (2016) 7:12:2246

IC50	6		J Med Chem, (2017) 60:16:6998	28714688

IC50	6		Journal of Medicinal Chemistry, (2017) None:16:6998	28714688

BRD1

Tchem

Bromodomain-containing protein 1

8 Activities

Items per page:

1 – 8 of 8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.97

IC50	7.34		J Med Chem, (2017) 60:16:6998	28714688

Kd	6.97		MedChemComm, (2015) 6:9:1587

Kd	6.97		MedChemComm, (2016) 7:12:2246

Kd	6.96		J. Med. Chem., (2016) 59:4:1271	26572217

Kd	6.96		J Med Chem, (2017) 60:16:6998	28714688

IC50	6.5		Journal of Medicinal Chemistry, (2017) None:16:6998	28714688

IC50	6.21		J Med Chem, (2017) 60:16:6998	28714688

BRD9

Tchem

Bromodomain-containing protein 9

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.28		J Med Chem, (2017) 60:16:6998	28714688

Kd	6		J Med Chem, (2017) 60:16:6998	28714688

BRD7

Tchem

Bromodomain-containing protein 7

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.85		J Med Chem, (2017) 60:16:6998	28714688