Pharos : Ligand Details - 3W776L4SJ9VG

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: SAR260301

PubChem: 49854424

PubChem: 135565159

Guide to Pharmacology: 8793

ChEMBL: CHEMBL3112866

LyCHI: 3W776L4SJ9VG

Target Activities

Explore Associated and Predicted Targets

AKT1

Tchem

RAC-alpha serine/threonine-protein kinase

5 Activities

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1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.3		None, (2015) None:None:None

IC50	8.05		None, (2015) None:None:None

IC50	7.8		None, (2015) None:None:None

IC50	7.72		None, (2015) None:None:None

IC50	7.57		None, (2015) None:None:None

PIK3CB

Tchem

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.64			24387221

IC50	7.64		J. Med. Chem., (2014) 57:3:903	24387221

PIK3C3

Tchem

Phosphatidylinositol 3-kinase catalytic subunit type 3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.74			24387221

PIK3CA

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.81			24387221

PIK3CD

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.33			24387221

PIK3C2G

Tchem

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.42			24387221