CHEMBL4557278
Ligand Summary
Name: (5-(4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)-3-fluoropicolinoyl)-L-glutamic Acid
PubChem: 155554671
ChEMBL: CHEMBL4557278
LyCHI: 34G1G4DA58HR
Target Activities
SLC46A1
Proton-coupled folate transporter
3 Activities
FOLR2
Folate receptor beta
2 Activities
FOLR1
Folate receptor alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.16 | J Med Chem, (2018) 61:9:4228 | ||||
GART
Trifunctional purine biosynthetic protein adenosine-3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.7 | J Med Chem, (2018) 61:9:4228 | ||||
SLC19A1
Folate transporter 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.33 | J Med Chem, (2018) 61:9:4228 | ||||