Pharos : Ligand Details - 2TDQ5QA5TCKU

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: US9163011, 3

PubChem: 71274016

ChEMBL: CHEMBL2386721

LyCHI: 2TDQ5QA5TCKU

Target Activities

Explore Associated and Predicted Targets

BACE2

Tchem

Beta-secretase 2

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.15		ACS Med. Chem. Lett., (2013) 4:5:433	24900690

IC50	6.85		None, (2015) None:None:None

BACE1

Tchem

Beta-secretase 1

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.54		ACS Med. Chem. Lett., (2013) 4:5:433	24900690

IC50	7.54		None, (2015) None:None:None

APP

Tchem

Amyloid-beta A4 protein

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.15		None, (2015) None:None:None