CHEMBL169046
Ligand Summary
Name: 25-hydroxycholesterol
PubChem: 65094
Guide to Pharmacology: 2885
ChEMBL: CHEMBL169046
LyCHI: 2QCJZ2M2NMC4
Target Activities
RORC
Nuclear receptor ROR-gamma
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.7 | Bioorg. Med. Chem. Lett., (2014) 24:24:5769 | ||||
EC50 | 7.7 | MedChemComm, (2013) 4:5:764 | ||||
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reductase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.52 | J. Med. Chem., (1994) 37:15:2343 | ||||
SREBF2
Sterol regulatory element-binding protein 2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.52 | J. Med. Chem., (2011) 54:13:4923 | ||||
GPR183
G-protein coupled receptor 183
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.9 | |||||