CHEMBL23296
Ligand Summary
Name: {3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid
PubChem: 9935197
Guide to Pharmacology: 2688
ChEMBL: CHEMBL23296
LyCHI: 2PMS3BKY3XFN
Target Activities
NR1H3
Oxysterols receptor LXR-alpha
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.45 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
EC50 | 7.45 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
IC50 | 7.45 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
IC50 | 7.45 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
EC50 | 7.46 | J. Nat. Prod., (2005) 68:8:1247 | ||||
IC50 | 7.5 | Bioorg. Med. Chem. Lett., (2006) 16:11:3055 | ||||
7.9 | ||||||
NR1H2
Oxysterols receptor LXR-beta
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.55 | Bioorg. Med. Chem. Lett., (2006) 16:11:3055 | ||||
IC50 | 7.6 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
IC50 | 7.6 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
EC50 | 7.79 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
EC50 | 7.79 | Bioorg. Med. Chem. Lett., (2005) 15:11:2824 | ||||
EC50 | 7.8 | J. Nat. Prod., (2005) 68:8:1247 | ||||
8.2 | ||||||
PPARD
Peroxisome proliferator-activated receptor delta
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8 | Bioorg. Med. Chem. Lett., (2003) 13:7:1277 | ||||
EC50 | 8.1 | Eur. J. Med. Chem., (2012) 53:None:190 | ||||
EC50 | 8.3 | Bioorg. Med. Chem. Lett., (2003) 13:7:1277 | ||||
IC50 | 8.4 | Bioorg. Med. Chem. Lett., (2006) 16:11:3055 | ||||
9 | ||||||