Aurintricarboxylic acid
Ligand Summary
Target Activities
APEX1
DNA-(apurinic or apyrimidinic site) lyase
2 Activities
TDP1
Tyrosyl-DNA phosphodiesterase 1
2 Activities
CTH
Cystathionine gamma-lyase
2 Activities
POLI
DNA polymerase iota
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.12 | J Med Chem, (2016) 59:20:9321 | ||||
POLH
DNA polymerase eta
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.12 | J Med Chem, (2016) 59:20:9321 | ||||
MPG
DNA-3-methyladenine glycosylase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.7 | Bioorg. Med. Chem., (2015) 23:5:1102 | ||||
C9
Complement component C9
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.3 | J Med Chem, (2018) 61:8:3253 | ||||