Pharos : Ligand Details - 23VGMAGCDCNW

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: (3R,5S)-N,1-Dibenzyl-3,5-dimethyl-1,2,3,5-tetrahydro-4H-pyrido-[3,4-e][1,4]diazepine-4-carboxamide

PubChem: 132991411

ChEMBL: CHEMBL3895005

LyCHI: 23VGMAGCDCNW

Target Activities

Explore Associated and Predicted Targets

CACNA1H

Tclin

Voltage-dependent T-type calcium channel subunit alpha-1H

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.99		J Med Chem, (2016) 59:23:10661	27933950

IC50	6.63		J Med Chem, (2016) 59:23:10661	27933950

CACNA1G

Tclin

Voltage-dependent T-type calcium channel subunit alpha-1G

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.86		J Med Chem, (2016) 59:23:10661	27933950

IC50	6.85		J Med Chem, (2016) 59:23:10661	27933950

CACNA1I

Tclin

Voltage-dependent T-type calcium channel subunit alpha-1I

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.96		J Med Chem, (2016) 59:23:10661	27933950

IC50	7.6		J Med Chem, (2016) 59:23:10661	27933950

CYP3A4

Tclin

Cytochrome P450 3A4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.64		J Med Chem, (2016) 59:23:10661	27933950