Pharos : Ligand Details - 1YPG9RMNJT7R

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: FRAX597

PubChem: 70934541

Guide to Pharmacology: 8939

ChEMBL: CHEMBL3609327

LyCHI: 1YPG9RMNJT7R

Target Activities

Explore Associated and Predicted Targets

PAK1

Tchem

Serine/threonine-protein kinase PAK 1

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.1			23960073

IC50	8.55		ACS Med Chem Lett, (2016) 7:12:1118	27994749

IC50	8.11		ACS Med. Chem. Lett., (2015) 6:7:776	26191365

PAK2

Tchem

Serine/threonine-protein kinase PAK 2

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.89			23960073

IC50	7.89		ACS Med. Chem. Lett., (2015) 6:7:776	26191365

PAK3

Tchem

Serine/threonine-protein kinase PAK 3

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.72			23960073

IC50	7.71		ACS Med. Chem. Lett., (2015) 6:7:776	26191365

PAK4

Tchem

Serine/threonine-protein kinase PAK 4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5			23960073