CHEMBL4099219
Ligand Summary
Name: 3-(Benzo[d][1,3]dioxol-5-ylmethyl)-1-(thiazol-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one
PubChem: 132489333
ChEMBL: CHEMBL4099219
LyCHI: 1WSNTGWWSK1C
Target Activities
PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.25 | J Med Chem, (2017) 60:15:6622 | ||||
PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.44 | J Med Chem, (2017) 60:15:6622 | ||||
PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.24 | J Med Chem, (2017) 60:15:6622 | ||||
PDE10A
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.82 | J Med Chem, (2017) 60:15:6622 | ||||