Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

FYN

Tclin

Tyrosine-protein kinase Fyn

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.64		Science, (2017) 358:6367:None	29191878

FLT3

Tclin

Receptor-type tyrosine-protein kinase FLT3

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.3		Science, (2017) 358:6367:None	29191878

PTK2

Tclin

Focal adhesion kinase 1

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.66		Science, (2017) 358:6367:None	29191878

NTRK1

Tclin

High affinity nerve growth factor receptor

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.22		Science, (2017) 358:6367:None	29191878

FGFR1

Tclin

Fibroblast growth factor receptor 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.05		Science, (2017) 358:6367:None	29191878

ABL2

Tchem

Tyrosine-protein kinase ABL2

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.1		Science, (2017) 358:6367:None	29191878

BMP2K

Tchem

BMP-2-inducible protein kinase

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.85		Science, (2017) 358:6367:None	29191878

EPHA7

Tchem

Ephrin type-A receptor 7

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.77		Science, (2017) 358:6367:None	29191878

BCR

Tclin

Breakpoint cluster region protein

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.52		Science, (2017) 358:6367:None	29191878

TNK1

Tchem

Non-receptor tyrosine-protein kinase TNK1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.52		Science, (2017) 358:6367:None	29191878

CDK17

Tchem

Cyclin-dependent kinase 17

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.3		Science, (2017) 358:6367:None	29191878

MAP4K1

Tchem

Mitogen-activated protein kinase kinase kinase kinase 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.82		Science, (2017) 358:6367:None	29191878

ACVR1

Tchem

Activin receptor type-1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.3		Science, (2017) 358:6367:None	29191878

AURKB

Tchem

Aurora kinase B

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.4		Science, (2017) 358:6367:None	29191878

ERCC2

Tchem

General transcription and DNA repair factor IIH helicase subunit XPD

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.02		Science, (2017) 358:6367:None	29191878

AURKA

Tchem

Aurora kinase A

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.52		Science, (2017) 358:6367:None	29191878

Q6ZSR9

Tchem

Uncharacterized protein FLJ45252

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.69		Science, (2017) 358:6367:None	29191878

EPHA1

Tchem

Ephrin type-A receptor 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.3		Science, (2017) 358:6367:None	29191878

RET

Tclin

Proto-oncogene tyrosine-protein kinase receptor Ret

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.05		Science, (2017) 358:6367:None	29191878

PLK4

Tchem

Serine/threonine-protein kinase PLK4

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.52		Science, (2017) 358:6367:None	29191878

PKN1

Tchem

Serine/threonine-protein kinase N1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.96		Science, (2017) 358:6367:None	29191878

EPHB6

Tchem

Ephrin type-B receptor 6

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.58		Science, (2017) 358:6367:None	29191878