CGS 21680
Ligand Summary
Name: CGS 21680
PubChem: 3086599
PubChem: 73348947
Guide to Pharmacology: 375
ChEMBL: CHEMBL331372
ChEMBL: CHEMBL2391907
LyCHI: 1NM1VZDNF6YB
Target Activities
ADORA2A
Adenosine receptor A2a
33 Activities
Items per page:
1 – 10 of 33
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.72 | |||||
EC50 | 8.67 | ACS Med. Chem. Lett., (2014) 5:9:1043 | ||||
Kd | 8.37 | J. Med. Chem., (1997) 40:16:2588 | ||||
Kd | 8.36 | ACS Med. Chem. Lett., (2014) 5:9:1043 | ||||
Kd | 8.12 | J. Med. Chem., (1997) 40:16:2588 | ||||
Kd | 8.12 | J. Med. Chem., (1997) 40:16:2588 | ||||
Kd | 7.94 | J. Med. Chem., (1997) 40:16:2588 | ||||
EC50 | 7.9 | MedChemComm, (2014) 5:2:192 | ||||
Ki | 7.9 | J. Med. Chem., (2015) 58:7:3253 | ||||
EC50 | 7.73 | J. Med. Chem., (2015) 58:7:3253 | ||||
ADORA3
Adenosine receptor A3
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.23 | |||||
EC50 | 8 | MedChemComm, (2014) 5:2:192 | ||||
Ki | 7.17 | J. Med. Chem., (1999) 42:8:1384 | ||||
Ki | 7.17 | J. Med. Chem., (2004) 47:16:4041 | ||||
Ki | 7.17 | Bioorg. Med. Chem. Lett., (2013) 23:1:26 | ||||
Ki | 7.17 | J. Med. Chem., (2014) 57:9:3623 | ||||
Ki | 7.17 | J. Med. Chem., (2016) 59:3:788 | ||||
ADORA2B
Adenosine receptor A2b
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 5 | |||||
EC50 | 7.4 | MedChemComm, (2014) 5:2:192 | ||||
ADORA1
Adenosine receptor A1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 5.74 | |||||