CHEMBL1229205,CHEMBL1210423
Ligand Summary
Name: 3-[3-tert-Butylsulfanyl-1-[4-(5-methoxypyrimidin-2-yl)-benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid
PubChem: 46235580
PubChem: 46843035
ChEMBL: CHEMBL1229205
ChEMBL: CHEMBL1210423
LyCHI: 1M7TA9PC5CWZ
Target Activities
ALOX5AP
Arachidonate 5-lipoxygenase-activating protein
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.22 | J. Med. Chem., (2011) 54:23:8013 | ||||
IC50 | 8.7 | Bioorg. Med. Chem. Lett., (2010) 20:15:4598 | ||||
IC50 | 8.7 | J. Med. Chem., (2011) 54:23:8013 | ||||
IC50 | 7.09 | J. Med. Chem., (2011) 54:23:8013 | ||||
IC50 | 6.79 | J. Med. Chem., (2011) 54:23:8013 | ||||
CYP3A4
Cytochrome P450 3A4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.06 | J. Med. Chem., (2011) 54:23:8013 | ||||
CYP2C9
Cytochrome P450 2C9
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.35 | J. Med. Chem., (2011) 54:23:8013 | ||||