Mivebresib
Ligand Summary
Target Activities
BRD4
Bromodomain-containing protein 4
15 Activities
Items per page:
1 – 10 of 15
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9 | Bioorg Med Chem, (2018) 26:12:3399 | ||||
IC50 | 9 | J Med Chem, (2020) 63:8:3956 | ||||
Ki | 8.85 | None, (2016) None:None:None | ||||
Ki | 8.82 | J Med Chem, (2017) 60:20:8369 | ||||
Ki | 8.82 | Bioorg Med Chem Lett, (2018) 28:10:1804 | ||||
IC50 | 8.57 | J Med Chem, (2020) 63:8:3956 | ||||
Ki | 8.46 | None, (2016) None:None:None | ||||
Ki | 7.82 | Bioorg Med Chem, (2017) 25:8:2482 | ||||
EC50 | 7.7 | J Med Chem, (2017) 60:20:8369 | ||||
IC50 | 7.7 | Bioorg Med Chem Lett, (2018) 28:10:1804 | ||||
EP300
Histone acetyltransferase p300
2 Activities
TSPO
Translocator protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.1 | J Med Chem, (2017) 60:20:8369 | ||||
BRD2
Bromodomain-containing protein 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 9 | J Med Chem, (2017) 60:20:8369 | ||||
BRDT
Bromodomain testis-specific protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.66 | J Med Chem, (2017) 60:20:8369 | ||||
BRD3
Bromodomain-containing protein 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.91 | J Med Chem, (2017) 60:20:8369 | ||||