GDC-0152
Ligand Summary
Name: GDC-0152
PubChem: 46940575
PubChem: 57522797
Guide to Pharmacology: 7733
ChEMBL: CHEMBL2063869
ChEMBL: CHEMBL2063868
LyCHI: 1HRMQMVA675Y
Target Activities
XIAP
E3 ubiquitin-protein ligase XIAP
11 Activities
Items per page:
1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.55 | |||||
IC50 | 7.68 | J Med Chem, (2019) 62:11:5616 | ||||
IC50 | 7.68 | J Med Chem, (2019) 62:11:5616 | ||||
Ki | 7.55 | J. Med. Chem., (2012) 55:9:4101 | ||||
Kd | 7.55 | J Med Chem, (2019) 62:12:5750 | ||||
Ki | 7.46 | J. Med. Chem., (2012) 55:9:4101 | ||||
IC50 | 7.28 | J Med Chem, (2018) 61:14:6350 | ||||
Kd | 7.06 | J Med Chem, (2018) 61:14:6350 | ||||
Ki | 6.95 | J. Med. Chem., (2012) 55:9:4101 | ||||
Kd | 6.95 | J Med Chem, (2019) 62:12:5750 | ||||