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Target Filters...

Development Level

Tbio 68 | 11,445
Tchem 13 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal ovary morphology 1 | 7
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal thymus morphology 1 | 7
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged thymus 1 | 5
fusion of vertebral arches 1 | 7
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
polycystic kidney 1 | 15
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 56 | 11,493
ovarian cancer 55 | 8,520
lung cancer 48 | 4,740
osteosarcoma 41 | 7,950
Cancer 38 | 2,499
medulloblastoma, large-cell 38 | 6,241
psoriasis 36 | 6,694
group 3 medulloblastoma 35 | 4,104
atypical teratoid / rhabdoid tumor 30 | 5,112
glioblastoma 30 | 5,792
Breast cancer 29 | 3,578
malignant mesothelioma 24 | 3,232
lung adenocarcinoma 22 | 2,716
non-small cell lung cancer 18 | 2,890
primitive neuroectodermal tumor 18 | 3,035
Waldenstrons macroglobulinemia 17 | 765
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Multiple myeloma 15 | 1,332
Small head 15 | 374
colon cancer 15 | 1,478
ependymoma 15 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Autosomal recessive predisposition 14 | 1,442
oligodendroglioma 14 | 2,850
Intellectual disability 13 | 1,016
Kidney cancer 13 | 2,613
Short stature 13 | 531
Cognitive delay 12 | 608
Dull intelligence 12 | 645
Global developmental delay 12 | 608
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental and motor retardation 12 | 608
Mental deficiency 12 | 645
Poor school performance 12 | 645
adrenocortical carcinoma 12 | 1,428
breast carcinoma 12 | 1,638
invasive ductal carcinoma 12 | 2,951
nasopharyngeal carcinoma 12 | 1,058
Xeroderma pigmentosum 11 | 43
adult high grade glioma 11 | 3,801
pancreatic cancer 11 | 2,398
Pick disease 10 | 1,894
astrocytoma 10 | 1,146
ductal carcinoma in situ 10 | 1,745
lung carcinoma 10 | 2,843
Prostatic Neoplasms 9 | 495
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
ulcerative colitis 9 | 1,819
Ataxia telangiectasia 8 | 34
Decreased platelet count 8 | 111
Dyskeratosis congenita 8 | 24
Endometriosis 8 | 540
Fanconi anemia 8 | 56
Fetal Growth Retardation 8 | 189
Infant, Small for Gestational Age 8 | 176
Intrauterine retardation 8 | 176
Melanoma 8 | 711
Thrombocytopenia 8 | 197
astrocytic glioma 8 | 2,597
diabetes mellitus 8 | 1,728
non primary Sjogren syndrome sicca 8 | 891
subependymal giant cell astrocytoma 8 | 2,287
Glioma 7 | 74
Nijmegen breakage syndrome 7 | 24
Rheumatoid arthritis 7 | 1,191
gastric carcinoma 7 | 807
hepatocellular carcinoma 7 | 547
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non-small cell lung carcinoma 7 | 317
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Anemia 6 | 365
Dry skin 6 | 75
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Seizures 6 | 596
Stomach Neoplasms 6 | 300
Werner syndrome 6 | 29
Xerosis 6 | 75
acute myeloid leukemia 6 | 783
cystic fibrosis 6 | 1,696
hypopigmented skin patch 6 | 59
pancreatic carcinoma 6 | 562
Astrocytoma, Pilocytic 5 | 3,081
Cockayne syndrome 5 | 60
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Highly variable clinical phenotype 5 | 150
Highly variable phenotype and severity 5 | 150
Pediatric failure to thrive 5 | 365
Phenotypic variability 5 | 150
esophageal adenocarcinoma 5 | 737
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
progressive supranuclear palsy 5 | 676

Tissue

Endocrine System 85 | 18,159
Blood and immune system 83 | 16,909
Digestive Tract 83 | 17,369
Female tissues 83 | 17,400
Liver and Pancreas 83 | 16,750
Male tissues 83 | 17,142
Respiratory system 82 | 16,393
Skin and soft tissues 82 | 17,230
Urinary Tract 82 | 16,678
Nervous System 81 | 16,725
Cardiovascular System 80 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 12 | 4,145
Epigenetic 6 | 242
Transcription Factor 6 | 1,400
Kinase 2 | 634
TF/Epigenetic 1 | 38

GO Component

nuclear chromosome, telomeric ... 85 | 85
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability