Development Level

Tclin 50 | 613
Tbio 19 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 22 | 99

IMPC Phenotype

abnormal behavior 5 | 298
hyperactivity 4 | 148
increased mean corpuscular vol... 3 | 92
abnormal behavioral response t... 2 | 66
increased bone mineral content 2 | 108
abnormal brain morphology 1 | 13
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased cardiac stroke volum... 1 | 6
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
kyphosis 1 | 5
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10

Disease

Carcinoma 63 | 11,493
Multiple Sclerosis 42 | 540
Eaton-Lambert syndrome 40 | 40
ependymoma 36 | 4,679
medulloblastoma, large-cell 35 | 6,241
glioblastoma 33 | 5,792
adult high grade glioma 30 | 3,801
atypical teratoid / rhabdoid tumor 30 | 5,112
Astrocytoma, Pilocytic 28 | 3,081
Kidney cancer 26 | 2,613
group 3 medulloblastoma 26 | 4,104
osteosarcoma 23 | 7,950
primitive neuroectodermal tumor 22 | 3,035
oligodendroglioma 21 | 2,850
astrocytic glioma 19 | 2,597
psoriasis 19 | 6,694
lung cancer 18 | 4,740
ovarian cancer 18 | 8,520
lung carcinoma 17 | 2,843
malignant mesothelioma 15 | 3,232
Atrial Fibrillation 14 | 124
Epilepsy 14 | 792
Long QT syndrome 13 | 39
subependymal giant cell astrocytoma 13 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
cystic fibrosis 11 | 1,696
pituitary cancer 11 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Breast cancer 9 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Brugada syndrome 8 | 29
Pick disease 8 | 1,894
Birk-Barel syndrome 7 | 8
Heart disease 7 | 306
Intellectual disability 7 | 1,016
Melanoma 7 | 711
Schizophrenia 7 | 1,160
Skin cancer 7 | 469
adrenocortical carcinoma 7 | 1,428
lung adenocarcinoma 7 | 2,716
progressive supranuclear palsy 7 | 676
Bipolar Disorder 6 | 666
Liver cancer 6 | 604
Muscle hypotonia 6 | 571
Seizures 6 | 596
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
invasive ductal carcinoma 6 | 2,951
Acquired metabolic disease 5 | 336
Cardiac arrest 5 | 36
Episodic ataxia 5 | 22
General anesthesia 5 | 53
Myoclonus 5 | 74
Paroxysmal atrial fibrillation 5 | 14
Type 2 diabetes mellitus 5 | 272
Ventricular Fibrillation 5 | 17
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
sonic hedgehog group medulloblastoma 5 | 467
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 4 | 21
Atrioventricular block 4 | 35
Autosomal recessive predisposition 4 | 1,442
Cardiomyopathy 4 | 116
Catecholaminergic polymorphic ventricular tachycardia 4 | 12
Cerebellar Ataxia 4 | 304
Familial atrial fibrillation 4 | 23
Heart conduction disease 4 | 83
Infantile onset 4 | 238
Mental Depression 4 | 333
Neurodegenerative disease 4 | 414
Partial Epilepsy Treatment Adjunct 4 | 16
Prolonged QT interval 4 | 15
Romano-Ward Syndrome 4 | 12
Short QT syndrome 4 | 12
Sudden Cardiac Death 4 | 29
Syncope 4 | 22
Timothy syndrome 4 | 11
Torsades de Pointes 4 | 8
non-small cell lung cancer 4 | 2,890
Amyotrophic lateral sclerosis 3 | 451
Brugada Syndrome (disorder) 3 | 15
Cardiac Arrhythmia 3 | 103
Chronic obstructive pulmonary disease 3 | 184
Diabetes Mellitus, Type 2 3 | 142
Dysarthria 3 | 192
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Sensorineural hearing loss 3 | 106
Tremor 3 | 113
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 74 | 18,159
Nervous System 70 | 16,725
Digestive Tract 67 | 17,369
Female tissues 67 | 17,400
Male tissues 66 | 17,142
Skin and soft tissues 64 | 17,230
Liver and Pancreas 61 | 16,750
Urinary Tract 59 | 16,678
Respiratory system 57 | 16,393
Blood and immune system 56 | 16,909
Cardiovascular System 49 | 15,192

Target Family

Ion Channel 74 | 344
Non-IDG 1 | 12,091

UniProt Keyword

Potassium channel 75 | 75
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kv channel-interacting protein 2 KCNIP2 Tbio Ion Channel -1.86621 71.6 314
Potassium voltage-gated channel subfamily A member 10 KCNA10 Tclin Ion Channel -1.09844 13.3 65
Trimeric intracellular cation channel type A TMEM38A Tbio Ion Channel -0.83405 6.81 113
Potassium voltage-gated channel subfamily G member 4 KCNG4 Tclin Ion Channel -0.85862 6.96 68
Potassium voltage-gated channel subfamily C member 4 KCNC4 Tclin Ion Channel -1.75478 56.8 213