Development Level

Tbio 44 | 11,651
Tchem 21 | 1,388
Tclin 5 | 612
Tdark 2 | 6,593

IMPC Phenotype

abnormal lens morphology 4 | 81
decreased vertical activity 4 | 208
cataract 3 | 92
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 18
absent optic nerve 1 | 2
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating phosphat... 1 | 26
increased circulating unsatura... 1 | 1
increased grip strength 1 | 41
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 54 | 11,493
psoriasis 44 | 6,694
ovarian cancer 36 | 8,520
Obesity 34 | 678
osteosarcoma 28 | 7,950
medulloblastoma, large-cell 26 | 6,241
diabetes mellitus 25 | 1,728
invasive ductal carcinoma 24 | 2,951
lung cancer 24 | 4,740
malignant mesothelioma 23 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
ductal carcinoma in situ 22 | 1,745
glioblastoma 22 | 5,792
Atherosclerosis 18 | 291
atypical teratoid / rhabdoid tumor 18 | 5,112
ependymoma 18 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Cancer 17 | 2,499
Lipid metabolism disorder 17 | 114
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
lung carcinoma 17 | 2,843
Atopic dermatitis 16 | 952
Breast cancer 16 | 3,578
Coronary artery disease 16 | 268
breast carcinoma 16 | 1,638
group 3 medulloblastoma 16 | 4,104
interstitial cystitis 16 | 2,312
Fatty liver disease 15 | 103
Liver Cirrhosis, Experimental 15 | 769
pancreatic cancer 15 | 2,398
Astrocytoma, Pilocytic 14 | 3,081
colon cancer 14 | 1,478
active Crohn's disease 13 | 922
astrocytoma 13 | 1,146
non-small cell lung cancer 13 | 2,890
pituitary cancer 13 | 1,972
ulcerative colitis 13 | 1,819
Schizophrenia 12 | 1,160
active ulcerative colitis 12 | 764
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
oligodendroglioma 12 | 2,850
tuberculosis 12 | 2,010
fibroadenoma 11 | 559
lung adenocarcinoma 11 | 2,716
Autosomal recessive predisposition 10 | 1,442
adrenocortical carcinoma 10 | 1,428
primitive neuroectodermal tumor 10 | 3,035
Epilepsy 9 | 792
Hypertension 9 | 396
Rheumatoid arthritis 9 | 1,191
nephrosclerosis 9 | 333
subependymal giant cell astrocytoma 9 | 2,287
Carcinoma, Hepatocellular 8 | 228
Hypertensive disease 8 | 292
Hypoglycemia 8 | 152
Kidney cancer 8 | 2,613
Liver carcinoma 8 | 240
Seizures 8 | 596
acute quadriplegic myopathy 8 | 1,158
cystic fibrosis 8 | 1,696
group 4 medulloblastoma 8 | 1,855
mucosa-associated lymphoid tissue lymphoma 8 | 484
Diabetes Mellitus, Experimental 7 | 108
Heart disease 7 | 306
Hepatomegaly 7 | 285
Hyperglycemia 7 | 137
Kidney disease 7 | 430
Myocardial Ischemia 7 | 169
cutaneous lupus erythematosus 7 | 1,057
nasopharyngeal carcinoma 7 | 1,058
pediatric high grade glioma 7 | 1,064
Animal Mammary Neoplasms 6 | 136
Breast Neoplasms 6 | 445
Chemical and Drug Induced Liver Injury 6 | 195
Heart failure 6 | 162
Hypercholesterolemia 6 | 44
Hypertriglyceridemia 6 | 17
Liver Failure 6 | 73
Mammary Neoplasms 6 | 425
Mammary Neoplasms, Animal 6 | 136
Mammary Neoplasms, Experimental 6 | 154
Pick disease 6 | 1,894
Polycystic ovary syndrome 6 | 360
Steatohepatitis 6 | 44
aldosterone-producing adenoma 6 | 665
Adrenoleukodystrophy 5 | 29
Bipolar Disorder 5 | 666
Cerebrovascular disease 5 | 238
Cholestasis 5 | 155
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Liver disease 5 | 237
Muscle hypotonia 5 | 571
Osteoporosis 5 | 363
Zellweger syndrome 5 | 37
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
dermatomyositis 5 | 966
hereditary spastic paraplegia 5 | 318

Tissue

Endocrine System 72 | 18,159
Digestive Tract 71 | 17,369
Female tissues 71 | 17,400
Liver and Pancreas 70 | 16,750
Skin and soft tissues 70 | 17,230
Blood and immune system 68 | 16,909
Male tissues 68 | 17,142
Urinary Tract 68 | 16,678
Nervous System 66 | 16,725
Respiratory system 65 | 16,393
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 26 | 4,145
Nuclear Receptor 7 | 48
Kinase 6 | 634
Transporter 5 | 473

KEGG Pathway

PPAR signaling pathway 72 | 72
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycerol kinase 2 GK2 Tdark Kinase -0.50515 3.20 207
Phospholipid transfer protein PLTP Tbio Non-IDG -2.53404 383.2 232