Development Level

Tbio 61 | 11,651
Tchem 26 | 1,388
Tclin 3 | 612
Tdark 1 | 6,593

IMPC Phenotype

abnormal heart morphology 3 | 162
enlarged heart 3 | 210
increased bone mineral content 3 | 108
preweaning lethality, complete... 3 | 979
short tibia 3 | 97
small adrenal glands 3 | 16
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
increased circulating potassiu... 2 | 29
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
mydriasis 1 | 6
premature death 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small kidney 1 | 16
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Carcinoma 69 | 11,493
ovarian cancer 59 | 8,520
glioblastoma 45 | 5,792
Autosomal recessive predisposition 43 | 1,442
psoriasis 43 | 6,694
osteosarcoma 40 | 7,950
lung cancer 33 | 4,740
malignant mesothelioma 30 | 3,232
medulloblastoma, large-cell 30 | 6,241
Breast cancer 28 | 3,578
Astrocytoma, Pilocytic 27 | 3,081
Cancer 26 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
atypical teratoid / rhabdoid tumor 25 | 5,112
Hepatomegaly 24 | 285
diabetes mellitus 24 | 1,728
ependymoma 23 | 4,679
invasive ductal carcinoma 23 | 2,951
Epilepsy 22 | 792
Splenomegaly 22 | 190
subependymal giant cell astrocytoma 22 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Intellectual disability 20 | 1,016
Seizures 20 | 596
tuberculosis 20 | 2,010
Muscle hypotonia 19 | 571
adult high grade glioma 19 | 3,801
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Poor school performance 18 | 645
lung carcinoma 18 | 2,843
pancreatic cancer 18 | 2,398
Coarse facial features 17 | 108
Congenital deafness 17 | 185
Deafness 17 | 198
Hearing Loss, Partial 17 | 185
Multiple myeloma 17 | 1,332
Thickened facial skin with coarse facial features 17 | 108
astrocytoma 17 | 1,146
hearing impairment 17 | 199
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
pituitary cancer 17 | 1,972
group 3 medulloblastoma 16 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Duchenne muscular dystrophy 15 | 601
cutaneous lupus erythematosus 15 | 1,057
ductal carcinoma in situ 15 | 1,745
interstitial cystitis 15 | 2,312
juvenile dermatomyositis 15 | 1,187
non-small cell lung cancer 15 | 2,890
ulcerative colitis 15 | 1,819
Short stature 14 | 531
Kidney cancer 13 | 2,613
Mucopolysaccharidosis 13 | 26
Neurodegenerative disease 13 | 414
adrenocortical carcinoma 13 | 1,428
oligodendroglioma 13 | 2,850
Atopic dermatitis 12 | 952
Cerebellar Ataxia 12 | 304
Rheumatoid arthritis 12 | 1,191
breast carcinoma 12 | 1,638
cystic fibrosis 12 | 1,696
esophageal adenocarcinoma 12 | 737
group 4 medulloblastoma 12 | 1,855
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Acquired scoliosis 11 | 281
Cognitive delay 11 | 608
Curvature of spine 11 | 282
Global developmental delay 11 | 608
Hernia, Inguinal 11 | 89
Mental and motor retardation 11 | 608
Pfaundler-Hurler Syndrome 11 | 12
colon cancer 11 | 1,478
pediatric high grade glioma 11 | 1,064
primary pancreatic ductal adenocarcinoma 11 | 1,109
Hyperkyphosis 10 | 111
Kyphosis deformity of spine 10 | 114
Liver Cirrhosis, Experimental 10 | 769
Osteoporosis 10 | 363
acute quadriplegic myopathy 10 | 1,158
dermatomyositis 10 | 966
non primary Sjogren syndrome sicca 10 | 891
sonic hedgehog group medulloblastoma 10 | 467
Anemia 9 | 365
Down syndrome 9 | 499
Dysarthria 9 | 192
Gangliosidosis 9 | 20
Hydrocephalus 9 | 152
Hyperreflexia 9 | 209
Joint stiffness 9 | 84
Macroglossia 9 | 65
Myoclonus 9 | 74
Recurrent respiratory infections 9 | 141
Schizophrenia 9 | 1,160
Short neck 9 | 140
astrocytic glioma 9 | 2,597
primary Sjogren syndrome 9 | 735

Tissue

Endocrine System 90 | 18,159
Blood and immune system 89 | 16,909
Digestive Tract 89 | 17,369
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Male tissues 89 | 17,142
Nervous System 89 | 16,725
Skin and soft tissues 89 | 17,230
Urinary Tract 89 | 16,678
Cardiovascular System 85 | 15,192
Respiratory system 85 | 16,393

Target Family

Enzyme 47 | 4,145
Non-IDG 42 | 12,091
Kinase 1 | 634
Transporter 1 | 473

GO Component

lysosomal lumen 91 | 91
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cation-transporting ATPase 13A2 ATP13A2 Tbio Transporter -2.03880 111.0 150
Glycogenin-1 GYG1 Tbio Enzyme -1.92315 75.8 152
Aggrecan core protein ACAN Tbio Non-IDG -3.36238 2138.5 0
Ribonuclease T2 RNASET2 Tbio Enzyme -1.63436 37.4 133
N-acylethanolamine-hydrolyzing acid amidase NAAA Tchem Enzyme -2.67716 463.4 152
Cathepsin L1 CTSL Tchem Enzyme -3.39489 2387.3 416
Lysosome membrane protein 2 SCARB2 Tbio Non-IDG -2.40121 240.5 282
Biglycan BGN Tbio Non-IDG -2.73039 529.9 267
Legumain LGMN Tchem Enzyme -2.36019 233.2 207
HLA class II histocompatibility antigen gamma chain CD74 Tchem Non-IDG -2.44232 286.2 1032