Development Level

Tchem 41 | 1,598
Tbio 40 | 11,445
Tclin 23 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
increased neutrophil cell numb... 4 | 46
abnormal gait 3 | 69
decreased body weight 3 | 161
increased mean corpuscular hem... 3 | 96
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
decreased bone mineral content 2 | 151
decreased circulating creatini... 2 | 39
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
thrombocytopenia 2 | 56
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased heart left ventricle... 1 | 4
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 85 | 11,493
Cancer 81 | 2,499
ovarian cancer 74 | 8,520
osteosarcoma 68 | 7,950
glioblastoma 59 | 5,792
lung cancer 53 | 4,740
psoriasis 50 | 6,694
atypical teratoid / rhabdoid tumor 48 | 5,112
medulloblastoma, large-cell 48 | 6,241
Breast cancer 42 | 3,578
ependymoma 39 | 4,679
Kidney cancer 38 | 2,613
adult high grade glioma 34 | 3,801
subependymal giant cell astrocytoma 29 | 2,287
group 3 medulloblastoma 28 | 4,104
Schizophrenia 27 | 1,160
Astrocytoma, Pilocytic 26 | 3,081
primitive neuroectodermal tumor 26 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
invasive ductal carcinoma 25 | 2,951
malignant mesothelioma 25 | 3,232
oligodendroglioma 25 | 2,850
Rheumatoid arthritis 24 | 1,191
diabetes mellitus 24 | 1,728
lung carcinoma 23 | 2,843
non-small cell lung cancer 23 | 2,890
Vascular disease 22 | 319
lung adenocarcinoma 22 | 2,716
Multiple myeloma 21 | 1,332
astrocytic glioma 21 | 2,597
astrocytoma 21 | 1,146
breast carcinoma 21 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
pancreatic cancer 21 | 2,398
tuberculosis 21 | 2,010
Breast Neoplasms 20 | 445
Mammary Neoplasms 20 | 425
Stomach Neoplasms 20 | 300
group 4 medulloblastoma 20 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Carcinoma, Hepatocellular 19 | 228
Liver carcinoma 19 | 240
Obesity 19 | 678
interstitial cystitis 19 | 2,312
Liver Cirrhosis, Experimental 18 | 769
Prostatic Neoplasms 18 | 495
pituitary cancer 18 | 1,972
Lung Neoplasms 17 | 232
ductal carcinoma in situ 17 | 1,745
Arthritis 16 | 290
Autosomal recessive predisposition 16 | 1,442
Neoplasm Metastasis 16 | 168
Pick disease 16 | 1,894
Alzheimer's disease 15 | 658
Intellectual disability 15 | 1,016
Short stature 15 | 531
colon cancer 15 | 1,478
Acquired scoliosis 14 | 281
Blepharoptosis 14 | 231
Carcinoma, Squamous Cell 14 | 110
Curvature of spine 14 | 282
Multiple Sclerosis 14 | 540
Pectus excavatum 14 | 100
Squamous cell carcinoma 14 | 129
adrenocortical carcinoma 14 | 1,428
cystic fibrosis 14 | 1,696
Adenocarcinoma 13 | 122
Byzanthine arch palate 13 | 194
Cell Transformation, Neoplastic 13 | 97
Downward slant of palpebral fissure 13 | 158
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mammary Neoplasms, Experimental 13 | 154
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Muscle hypotonia 13 | 571
Orbital separation excessive 13 | 244
Poor school performance 13 | 645
Renal Cell Carcinoma 13 | 214
acute quadriplegic myopathy 13 | 1,158
dermatomyositis 13 | 966
juvenile dermatomyositis 13 | 1,187
ulcerative colitis 13 | 1,819
Animal Mammary Neoplasms 12 | 136
Cognitive delay 12 | 608
Epilepsy 12 | 792
Frontal bossing 12 | 157
Global developmental delay 12 | 608
Heart disease 12 | 306
Hyperglycemia 12 | 137
Hypertension 12 | 396
Hypoplastic mandible condyle 12 | 275
Immune system cancer 12 | 140
Mammary Neoplasms, Animal 12 | 136
Mandibular hypoplasia 12 | 275
Mental and motor retardation 12 | 608
Micrognathism 12 | 275
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
primary pancreatic ductal adenocarcinoma 12 | 1,109
Asthma 11 | 385

Tissue

Digestive Tract 104 | 17,369
Endocrine System 104 | 18,159
Female tissues 104 | 17,400
Liver and Pancreas 104 | 16,750
Male tissues 104 | 17,142
Skin and soft tissues 104 | 17,230
Urinary Tract 104 | 16,678
Blood and immune system 103 | 16,909
Cardiovascular System 103 | 15,192
Nervous System 103 | 16,725
Respiratory system 103 | 16,393

Target Family

Non-IDG 38 | 12,091
Kinase 35 | 634
Enzyme 13 | 4,145
Transcription Factor 13 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
Transporter 1 | 473

PathwayCommons: netpath Pathway

http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 472 | 472
http://pathwaycommons.org/pc2/... 270 | 270
http://pathwaycommons.org/pc2/... 258 | 258
http://pathwaycommons.org/pc2/... 220 | 220
http://pathwaycommons.org/pc2/... 164 | 164
http://pathwaycommons.org/pc2/... 161 | 161
http://pathwaycommons.org/pc2/... 118 | 118
http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 98 | 98
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 76 | 76
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 73 | 73
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability