Development Level

Tbio 2,490 | 11,445
Tdark 750 | 6,588
Tchem 383 | 1,598
Tclin 178 | 613

Collection

RFA-RM-18-021 73 | 328
Ion Channel: IDG Consortium (T... 30 | 99
Kinase: IDG Consortium (Target... 29 | 125
GPCR: IDG Consortium (Targets) 15 | 126
Kinase: IDG Consortium (Comple... 10 | 37
GPCR: IDG Consortium (Complete... 6 | 25

IMPC Phenotype

preweaning lethality, complete... 153 | 979
preweaning lethality, incomple... 130 | 499
abnormal behavior 92 | 298
decreased total body fat amoun... 54 | 207
hyperactivity 54 | 148
abnormal bone structure 52 | 187
decreased vertical activity 48 | 208
embryonic lethality prior to t... 47 | 278
enlarged heart 47 | 210
increased lean body mass 43 | 172
hypoactivity 42 | 132
decreased bone mineral content 39 | 151
increased bone mineral content 38 | 108
abnormal embryo size 37 | 220
decreased grip strength 37 | 116
decreased body weight 36 | 161
increased circulating alkaline... 36 | 122
abnormal heart morphology 32 | 162
embryonic lethality prior to o... 32 | 239
increased total body fat amoun... 30 | 134
decreased circulating glucose ... 29 | 126
decreased lean body mass 29 | 135
increased startle reflex 29 | 112
decreased body length 28 | 101
decreased prepulse inhibition 28 | 82
cataract 27 | 92
abnormal seminal vesicle morph... 26 | 114
decreased circulating choleste... 26 | 93
increased or absent threshold ... 26 | 101
short tibia 24 | 97
abnormal lens morphology 23 | 81
decreased lymphocyte cell numb... 23 | 83
decreased startle reflex 23 | 75
male infertility 23 | 123
abnormal gait 21 | 69
decreased bone mineral density 21 | 126
decreased circulating HDL chol... 21 | 68
improved glucose tolerance 21 | 79
increased mean corpuscular hem... 21 | 96
decreased fasted circulating g... 20 | 65
decreased mean corpuscular vol... 20 | 79
increased circulating HDL chol... 20 | 80
limb grasping 20 | 41
decreased leukocyte cell numbe... 19 | 73
abnormal behavioral response t... 18 | 66
abnormal kidney morphology 18 | 65
abnormal sleep behavior 18 | 70
decreased circulating serum al... 18 | 82
decreased circulating triglyce... 18 | 79
decreased hemoglobin content 18 | 68
increased mean corpuscular vol... 18 | 92
abnormal coat-hair pigmentatio... 17 | 64
abnormal eye morphology 17 | 68
increased bone mineral density 17 | 72
increased heart weight 17 | 62
increased monocyte cell number 17 | 63
impaired glucose tolerance 16 | 75
increased circulating triglyce... 16 | 42
tremors 16 | 39
embryonic growth retardation 15 | 106
increased circulating chloride... 15 | 41
increased circulating choleste... 15 | 66
increased fasted circulating g... 15 | 76
prenatal lethality prior to he... 15 | 87
small testis 15 | 58
abnormal retina morphology 14 | 71
decreased circulating alkaline... 14 | 46
increased circulating sodium l... 14 | 71
increased hematocrit 14 | 46
small superior vagus ganglion 14 | 74
abnormal epididymis morphology 13 | 42
decreased circulating calcium ... 13 | 36
decreased circulating insulin ... 13 | 76
decreased hematocrit 13 | 46
decreased mean corpuscular hem... 13 | 50
decreased circulating alanine ... 12 | 47
decreased circulating amylase ... 12 | 28
decreased erythrocyte cell num... 12 | 62
female infertility 12 | 60
increased blood urea nitrogen ... 12 | 48
increased circulating creatini... 12 | 38
increased erythrocyte cell num... 12 | 39
increased mean platelet volume 12 | 45
abnormal locomotor behavior 11 | 24
abnormal skin morphology 11 | 50
abnormal spleen morphology 11 | 55
decreased circulating LDL chol... 11 | 38
edema 11 | 59
increased hemoglobin content 11 | 45
abnormal testis morphology 10 | 43
decreased caudal vertebrae num... 10 | 53
decreased circulating total pr... 10 | 49
decreased neutrophil cell numb... 10 | 42
decreased threshold for audito... 10 | 26
enlarged lymph nodes 10 | 37
enlarged spleen 10 | 41
increased circulating calcium ... 10 | 34
increased mean corpuscular hem... 10 | 36
thrombocytopenia 10 | 56
prolonged ST segment 9 | 36

Disease

adult high grade glioma 3,801 | 3,801
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 3,739 | 18,159
Nervous System 3,687 | 16,725
Digestive Tract 3,682 | 17,369
Female tissues 3,677 | 17,400
Skin and soft tissues 3,670 | 17,230
Male tissues 3,656 | 17,142
Urinary Tract 3,599 | 16,678
Liver and Pancreas 3,598 | 16,750
Blood and immune system 3,580 | 16,909
Respiratory system 3,539 | 16,393
Cardiovascular System 3,360 | 15,192

Target Family

Non-IDG 2,268 | 12,091
Enzyme 793 | 4,145
Transcription Factor 204 | 1,400
Kinase 162 | 634
Ion Channel 116 | 344
Transporter 105 | 473
GPCR 78 | 408
Epigenetic 42 | 242
Nuclear Receptor 13 | 48
oGPCR 11 | 421
TF/Epigenetic 9 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability