Development Level

Tbio 1,412 | 11,445
Tchem 259 | 1,598
Tdark 175 | 6,588
Tclin 71 | 613

Collection

RFA-RM-18-021 18 | 328
Kinase: IDG Consortium (Target... 11 | 125
Ion Channel: IDG Consortium (T... 6 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 157 | 979
preweaning lethality, incomple... 70 | 499
embryonic lethality prior to t... 54 | 278
embryonic lethality prior to o... 52 | 239
abnormal embryo size 33 | 220
decreased total body fat amoun... 28 | 207
abnormal behavior 24 | 298
decreased body weight 23 | 161
abnormal bone structure 22 | 187
increased lean body mass 20 | 172
increased startle reflex 20 | 112
hypoactivity 18 | 132
embryonic growth retardation 17 | 106
enlarged heart 17 | 210
abnormal seminal vesicle morph... 16 | 114
decreased bone mineral content 16 | 151
increased grip strength 16 | 41
hyperactivity 15 | 148
increased circulating alkaline... 15 | 122
increased mean corpuscular hem... 15 | 96
increased total body fat amoun... 15 | 134
decreased bone mineral density 14 | 126
decreased vertical activity 14 | 208
decreased circulating glucose ... 13 | 126
increased circulating HDL chol... 13 | 80
male infertility 12 | 123
abnormal heart morphology 11 | 162
abnormal retina morphology 11 | 71
decreased erythrocyte cell num... 11 | 62
decreased prepulse inhibition 11 | 82
decreased startle reflex 11 | 75
pallor 11 | 34
prenatal lethality prior to he... 11 | 87
decreased circulating alanine ... 10 | 47
decreased hemoglobin content 10 | 68
decreased mean corpuscular vol... 10 | 79
impaired glucose tolerance 10 | 75
increased bone mineral density 10 | 72
increased circulating choleste... 10 | 66
increased or absent threshold ... 10 | 101
small testis 10 | 58
abnormal behavioral response t... 9 | 66
decreased circulating insulin ... 9 | 76
decreased circulating triglyce... 9 | 79
decreased grip strength 9 | 116
decreased lean body mass 9 | 135
decreased leukocyte cell numbe... 9 | 73
decreased lymphocyte cell numb... 9 | 83
improved glucose tolerance 9 | 79
increased fasted circulating g... 9 | 76
increased mean corpuscular vol... 9 | 92
abnormal eye morphology 8 | 68
abnormal sleep behavior 8 | 70
decreased body length 8 | 101
decreased caudal vertebrae num... 8 | 53
decreased circulating aspartat... 8 | 34
decreased fasted circulating g... 8 | 65
decreased hematocrit 8 | 46
increased bone mineral content 8 | 108
increased monocyte cell number 8 | 63
abnormal gait 7 | 69
abnormal lens morphology 7 | 81
abnormal neural tube closure 7 | 46
abnormal skin morphology 7 | 50
cataract 7 | 92
decreased circulating HDL chol... 7 | 68
decreased mean corpuscular hem... 7 | 50
edema 7 | 59
enlarged lymph nodes 7 | 37
increased circulating calcium ... 7 | 34
increased circulating iron lev... 7 | 30
increased heart weight 7 | 62
pale yolk sac 7 | 25
short tibia 7 | 97
thrombocytopenia 7 | 56
abnormal embryo turning 6 | 31
abnormal epididymis morphology 6 | 42
abnormal lung morphology 6 | 26
decreased circulating alkaline... 6 | 46
decreased circulating calcium ... 6 | 36
decreased circulating chloride... 6 | 30
decreased circulating serum al... 6 | 82
decreased circulating sodium l... 6 | 22
decreased red blood cell distr... 6 | 41
hydrometra 6 | 53
increased circulating total pr... 6 | 28
increased mean platelet volume 6 | 45
increased neutrophil cell numb... 6 | 46
limb grasping 6 | 41
small superior vagus ganglion 6 | 74
abnormal coat-hair pigmentatio... 5 | 64
decreased circulating choleste... 5 | 93
enlarged spleen 5 | 41
increased body weight 5 | 25
increased circulating amylase ... 5 | 25
increased circulating phosphat... 5 | 26
increased mean corpuscular hem... 5 | 36
increased prepulse inhibition 5 | 32
prolonged QT interval 5 | 38
thrombocytosis 5 | 27

Disease

Carcinoma 1,325 | 11,493
ovarian cancer 1,185 | 8,520
osteosarcoma 988 | 7,950
medulloblastoma, large-cell 803 | 6,241
glioblastoma 795 | 5,792
psoriasis 791 | 6,694
lung cancer 701 | 4,740
atypical teratoid / rhabdoid tumor 639 | 5,112
ependymoma 562 | 4,679
Breast cancer 465 | 3,578
group 3 medulloblastoma 452 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 449 | 3,291
adult high grade glioma 443 | 3,801
malignant mesothelioma 436 | 3,232
Astrocytoma, Pilocytic 397 | 3,081
invasive ductal carcinoma 396 | 2,951
non-small cell lung cancer 391 | 2,890
Cancer 386 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 382 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 355 | 2,955
oligodendroglioma 354 | 2,850
lung adenocarcinoma 352 | 2,716
Kidney cancer 341 | 2,613
primitive neuroectodermal tumor 336 | 3,035
pancreatic cancer 326 | 2,398
lung carcinoma 315 | 2,843
astrocytic glioma 303 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 302 | 1,962
subependymal giant cell astrocytoma 301 | 2,287
Multiple myeloma 297 | 1,332
diabetes mellitus 293 | 1,728
interstitial cystitis 263 | 2,312
tuberculosis 255 | 2,010
Pick disease 248 | 1,894
ulcerative colitis 242 | 1,819
group 4 medulloblastoma 238 | 1,855
Autosomal recessive predisposition 233 | 1,442
acute quadriplegic myopathy 231 | 1,158
astrocytoma 226 | 1,146
ductal carcinoma in situ 212 | 1,745
juvenile dermatomyositis 212 | 1,187
pituitary cancer 211 | 1,972
Rheumatoid arthritis 206 | 1,191
colon cancer 204 | 1,478
breast carcinoma 203 | 1,638
dermatomyositis 184 | 966
adrenocortical carcinoma 175 | 1,428
cystic fibrosis 175 | 1,696
Waldenstrons macroglobulinemia 172 | 765
pediatric high grade glioma 161 | 1,064
Intellectual disability 160 | 1,016
Schizophrenia 157 | 1,160
cutaneous lupus erythematosus 152 | 1,057
primary pancreatic ductal adenocarcinoma 146 | 1,109
spina bifida 143 | 1,074
active Crohn's disease 141 | 922
Epilepsy 139 | 792
Liver Cirrhosis, Experimental 124 | 769
non primary Sjogren syndrome sicca 120 | 891
Alzheimer's disease 119 | 658
Seizures 116 | 596
Cognitive delay 114 | 608
Global developmental delay 114 | 608
Mental and motor retardation 114 | 608
Atopic dermatitis 109 | 952
Dull intelligence 107 | 645
Low intelligence 107 | 645
Mental Retardation 107 | 645
Mental deficiency 107 | 645
Poor school performance 107 | 645
nasopharyngeal carcinoma 107 | 1,058
Obesity 106 | 678
esophageal adenocarcinoma 106 | 737
primary Sjogren syndrome 106 | 735
active ulcerative colitis 101 | 764
Muscle hypotonia 100 | 571
Short stature 100 | 531
Duchenne muscular dystrophy 98 | 601
acute myeloid leukemia 95 | 783
aldosterone-producing adenoma 95 | 665
gastric carcinoma 95 | 807
Bipolar Disorder 93 | 666
Liver cancer 89 | 604
progressive supranuclear palsy 88 | 676
Down syndrome 85 | 499
medulloblastoma 85 | 720
Neurodegenerative disease 82 | 414
Endometriosis 81 | 540
autosomal dominant Emery-Dreifuss muscular dystrophy 80 | 510
Small head 79 | 374
Prostatic Neoplasms 78 | 495
Breast Neoplasms 76 | 445
Mammary Neoplasms 74 | 425
Amyotrophic lateral sclerosis 73 | 451
Depressive disorder 72 | 409
Melanoma 70 | 711
Failure to gain weight 69 | 365
Pediatric failure to thrive 69 | 365
Parkinson's disease 65 | 392
pancreatic carcinoma 65 | 562

Tissue

Endocrine System 1,879 | 18,159
Digestive Tract 1,875 | 17,369
Female tissues 1,871 | 17,400
Skin and soft tissues 1,868 | 17,230
Blood and immune system 1,857 | 16,909
Nervous System 1,852 | 16,725
Urinary Tract 1,852 | 16,678
Liver and Pancreas 1,851 | 16,750
Male tissues 1,851 | 17,142
Respiratory system 1,831 | 16,393
Cardiovascular System 1,792 | 15,192

Target Family

Non-IDG 1,099 | 12,091
Enzyme 542 | 4,145
Transporter 114 | 473
Kinase 83 | 634
Ion Channel 28 | 344
Transcription Factor 23 | 1,400
GPCR 15 | 408
Epigenetic 11 | 242
Nuclear Receptor 2 | 48

GO Component

membrane 1,917 | 1,917
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability