Development Level

Tbio 514 | 11,651
Tdark 127 | 6,593
Tchem 66 | 1,388
Tclin 14 | 612

Collection

RFA-RM-18-021 17 | 328
Kinase: IDG Consortium (Target... 13 | 125
Kinase: IDG Consortium (Comple... 8 | 37
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 71 | 979
preweaning lethality, incomple... 20 | 499
embryonic lethality prior to t... 19 | 278
abnormal behavior 17 | 298
abnormal embryo size 16 | 220
male infertility 13 | 123
embryonic lethality prior to o... 12 | 239
decreased total body fat amoun... 11 | 207
decreased body weight 10 | 161
increased circulating alkaline... 10 | 122
decreased vertical activity 9 | 208
hypoactivity 9 | 132
decreased body length 8 | 101
decreased bone mineral content 8 | 151
decreased circulating glucose ... 8 | 126
decreased lean body mass 8 | 135
hyperactivity 8 | 148
increased fasted circulating g... 8 | 76
prenatal lethality prior to he... 8 | 87
decreased bone mineral density 7 | 126
decreased grip strength 7 | 116
edema 7 | 59
embryonic growth retardation 7 | 106
impaired glucose tolerance 7 | 75
improved glucose tolerance 7 | 79
abnormal bone structure 6 | 187
abnormal cranium morphology 6 | 36
abnormal heart morphology 6 | 162
abnormal kidney morphology 6 | 65
abnormal retina morphology 6 | 71
decreased circulating choleste... 6 | 93
decreased circulating serum al... 6 | 82
enlarged heart 6 | 210
increased bone mineral content 6 | 108
increased bone mineral density 6 | 72
increased lean body mass 6 | 172
increased startle reflex 6 | 112
short tibia 6 | 97
abnormal sleep behavior 5 | 70
cataract 5 | 92
decreased startle reflex 5 | 75
female infertility 5 | 60
increased leukocyte cell numbe... 5 | 47
increased mean corpuscular hem... 5 | 96
small testis 5 | 58
abnormal behavioral response t... 4 | 66
abnormal craniofacial morpholo... 4 | 33
abnormal embryo turning 4 | 31
abnormal head morphology 4 | 10
abnormal lens morphology 4 | 81
abnormal spleen morphology 4 | 55
abnormal tail morphology 4 | 25
abnormal testis morphology 4 | 43
decreased caudal vertebrae num... 4 | 53
decreased circulating calcium ... 4 | 36
decreased leukocyte cell numbe... 4 | 73
increased circulating HDL chol... 4 | 80
increased hematocrit 4 | 46
increased mean corpuscular vol... 4 | 92
increased or absent threshold ... 4 | 101
increased total body fat amoun... 4 | 134
prenatal lethality 4 | 28
abnormal gait 3 | 69
abnormal humerus morphology 3 | 11
abnormal limb morphology 3 | 13
abnormal lung morphology 3 | 26
abnormal neural tube closure 3 | 46
abnormal pericardium morpholog... 3 | 26
abnormal retinal vasculature m... 3 | 27
abnormal seminal vesicle morph... 3 | 114
cardiovascular system phenotyp... 3 | 36
decreased blood urea nitrogen ... 3 | 51
decreased circulating HDL chol... 3 | 68
decreased circulating insulin ... 3 | 76
decreased lactate dehydrogenas... 3 | 16
decreased spleen weight 3 | 10
hemorrhage 3 | 23
increased body length 3 | 32
increased circulating glucose ... 3 | 24
increased circulating iron lev... 3 | 30
increased circulating sodium l... 3 | 71
increased grip strength 3 | 41
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
vertebral fusion 3 | 23
abnormal locomotor behavior 2 | 24
abnormal pancreas morphology 2 | 13
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
abnormal vertebrae morphology 2 | 18
decreased circulating potassiu... 2 | 20
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
increased anti-nuclear antigen... 2 | 19
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased prepulse inhibition 2 | 32
microphthalmia 2 | 26
tremors 2 | 39

Disease

Carcinoma 519 | 11,493
ovarian cancer 409 | 8,520
osteosarcoma 360 | 7,950
medulloblastoma, large-cell 304 | 6,241
glioblastoma 268 | 5,792
psoriasis 259 | 6,694
atypical teratoid / rhabdoid tumor 257 | 5,112
ependymoma 242 | 4,679
group 3 medulloblastoma 230 | 4,104
lung cancer 223 | 4,740
Breast cancer 181 | 3,578
adult high grade glioma 178 | 3,801
primitive neuroectodermal tumor 170 | 3,035
malignant mesothelioma 161 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 151 | 3,291
Kidney cancer 148 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 140 | 2,989
non-small cell lung cancer 134 | 2,890
oligodendroglioma 132 | 2,850
invasive ductal carcinoma 128 | 2,951
Cancer 117 | 2,499
Pick disease 114 | 1,894
astrocytic glioma 106 | 2,597
lung adenocarcinoma 106 | 2,716
Astrocytoma, Pilocytic 102 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 100 | 2,955
Autosomal recessive predisposition 95 | 1,442
Intellectual disability 95 | 1,016
adrenocortical carcinoma 91 | 1,428
subependymal giant cell astrocytoma 88 | 2,287
lung carcinoma 87 | 2,843
pancreatic cancer 87 | 2,398
breast carcinoma 84 | 1,638
ductal carcinoma in situ 83 | 1,745
interstitial cystitis 76 | 2,312
colon cancer 72 | 1,478
group 4 medulloblastoma 72 | 1,855
tuberculosis 69 | 2,010
Dull intelligence 64 | 645
Low intelligence 64 | 645
Mental Retardation 64 | 645
Mental deficiency 64 | 645
Poor school performance 64 | 645
ulcerative colitis 64 | 1,819
diabetes mellitus 60 | 1,728
nasopharyngeal carcinoma 60 | 1,058
Multiple myeloma 59 | 1,332
pituitary cancer 59 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 58 | 1,962
astrocytoma 57 | 1,146
acute quadriplegic myopathy 54 | 1,158
Cognitive delay 53 | 608
Global developmental delay 53 | 608
Mental and motor retardation 53 | 608
Schizophrenia 53 | 1,160
spina bifida 50 | 1,074
Rheumatoid arthritis 48 | 1,191
Atopic dermatitis 47 | 952
Short stature 47 | 531
dermatomyositis 47 | 966
chronic rhinosinusitis 45 | 512
juvenile dermatomyositis 44 | 1,187
pediatric high grade glioma 44 | 1,064
Endometriosis 42 | 540
Obesity 41 | 678
Ciliopathy 39 | 71
cystic fibrosis 39 | 1,696
Small head 38 | 374
active Crohn's disease 38 | 922
primary pancreatic ductal adenocarcinoma 38 | 1,109
progressive supranuclear palsy 38 | 676
Nystagmus 37 | 317
Epilepsy 35 | 792
Microcephaly 35 | 166
Polydactyly 35 | 107
non primary Sjogren syndrome sicca 35 | 891
Waldenstrons macroglobulinemia 33 | 765
medulloblastoma 33 | 720
Retinitis Pigmentosa 32 | 226
posterior fossa group B ependymoma 32 | 416
Amyotrophic lateral sclerosis 31 | 451
Seizures 31 | 596
esophageal adenocarcinoma 31 | 737
primary Sjogren syndrome 31 | 735
Neurodegenerative disease 30 | 414
cutaneous lupus erythematosus 30 | 1,057
tuberculosis and treatment for 6 months 30 | 409
Joubert syndrome 29 | 66
Liver cancer 29 | 604
acute myeloid leukemia 28 | 783
Bipolar Disorder 27 | 666
Nephronophthisis 27 | 80
aldosterone-producing adenoma 27 | 665
gastric cancer 27 | 459
Bardet-Biedl syndrome 26 | 51
Muscle hypotonia 26 | 571
hepatocellular carcinoma 26 | 547
Cataract 25 | 297
Congenital hypoplasia of penis 25 | 176
Liver Cirrhosis, Experimental 25 | 769

Tissue

Endocrine System 708 | 18,159
Skin and soft tissues 704 | 17,230
Female tissues 703 | 17,400
Male tissues 703 | 17,142
Digestive Tract 701 | 17,369
Blood and immune system 698 | 16,909
Liver and Pancreas 695 | 16,750
Nervous System 694 | 16,725
Respiratory system 694 | 16,393
Urinary Tract 694 | 16,678
Cardiovascular System 670 | 15,192

Target Family

Non-IDG 504 | 12,091
Enzyme 112 | 4,145
Kinase 58 | 634
Transcription Factor 20 | 1,400
Epigenetic 8 | 242
Transporter 8 | 473
Ion Channel 6 | 344
GPCR 3 | 408
Nuclear Receptor 2 | 48

Compartment GO Term

Microtubule organizing center 721 | 721
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability