Development Level

Tbio 195 | 11,651
Tdark 77 | 6,593
Tchem 5 | 1,388

IMPC Phenotype

preweaning lethality, complete... 29 | 979
embryonic lethality prior to t... 10 | 278
preweaning lethality, incomple... 8 | 499
abnormal embryo size 5 | 220
embryonic lethality prior to o... 5 | 239
abnormal bone structure 4 | 187
decreased circulating choleste... 4 | 93
decreased leukocyte cell numbe... 4 | 73
embryonic growth retardation 4 | 106
impaired glucose tolerance 4 | 75
abnormal behavior 3 | 298
decreased body weight 3 | 161
decreased circulating LDL chol... 3 | 38
decreased circulating glucose ... 3 | 126
decreased vertical activity 3 | 208
hypoactivity 3 | 132
increased circulating alkaline... 3 | 122
increased mean corpuscular vol... 3 | 92
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
abnormal coat-hair pigmentatio... 2 | 64
abnormal heart morphology 2 | 162
abnormal placenta size 2 | 20
abnormal spleen morphology 2 | 55
abnormal tooth morphology 2 | 24
anophthalmia 2 | 33
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased cardiac muscle contr... 2 | 11
decreased circulating aspartat... 2 | 34
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
enlarged heart 2 | 210
female infertility 2 | 60
fusion of vertebral arches 2 | 7
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating thyroxin... 2 | 7
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
thrombocytopenia 2 | 56
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
absent pinna reflex 1 | 23
absent spleen 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased food intake 1 | 13
decreased lean body mass 1 | 135
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
enlarged spleen 1 | 41
increased anti-nuclear antigen... 1 | 19
increased cardiac muscle contr... 1 | 8
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
pale liver 1 | 6
small testis 1 | 58

Disease

Carcinoma 222 | 11,493
ovarian cancer 155 | 8,520
osteosarcoma 137 | 7,950
medulloblastoma, large-cell 103 | 6,241
psoriasis 102 | 6,694
glioblastoma 91 | 5,792
group 3 medulloblastoma 81 | 4,104
atypical teratoid / rhabdoid tumor 77 | 5,112
ependymoma 77 | 4,679
Kidney cancer 62 | 2,613
lung cancer 59 | 4,740
adult high grade glioma 54 | 3,801
malignant mesothelioma 53 | 3,232
Breast cancer 50 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
primitive neuroectodermal tumor 39 | 3,035
oligodendroglioma 38 | 2,850
Pick disease 36 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
astrocytic glioma 34 | 2,597
lung carcinoma 34 | 2,843
subependymal giant cell astrocytoma 33 | 2,287
Astrocytoma, Pilocytic 30 | 3,081
invasive ductal carcinoma 30 | 2,951
lung adenocarcinoma 30 | 2,716
Intellectual disability 29 | 1,016
acute quadriplegic myopathy 29 | 1,158
non-small cell lung cancer 28 | 2,890
tuberculosis 28 | 2,010
group 4 medulloblastoma 25 | 1,855
pituitary cancer 23 | 1,972
diabetes mellitus 22 | 1,728
pancreatic cancer 22 | 2,398
colon cancer 21 | 1,478
Autosomal recessive predisposition 20 | 1,442
Multiple myeloma 20 | 1,332
Rheumatoid arthritis 20 | 1,191
interstitial cystitis 20 | 2,312
nasopharyngeal carcinoma 20 | 1,058
adrenocortical carcinoma 19 | 1,428
astrocytoma 18 | 1,146
pediatric high grade glioma 18 | 1,064
dermatomyositis 17 | 966
chronic rhinosinusitis 16 | 512
juvenile dermatomyositis 16 | 1,187
Cancer 15 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
progressive supranuclear palsy 15 | 676
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
Waldenstrons macroglobulinemia 14 | 765
ductal carcinoma in situ 14 | 1,745
spina bifida 14 | 1,074
breast carcinoma 13 | 1,638
Liver cancer 12 | 604
Schizophrenia 12 | 1,160
Short stature 12 | 531
non primary Sjogren syndrome sicca 12 | 891
Ciliopathy 11 | 71
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Mental and motor retardation 11 | 608
acute myeloid leukemia 11 | 783
cystic fibrosis 11 | 1,696
primary pancreatic ductal adenocarcinoma 11 | 1,109
gastric carcinoma 10 | 807
ulcerative colitis 10 | 1,819
Asphyxiating thoracic dystrophy 9 | 44
Melanoma 9 | 711
Optic Atrophy 9 | 242
Polydactyly 9 | 107
Retinitis Pigmentosa 9 | 226
Small head 9 | 374
cutaneous lupus erythematosus 9 | 1,057
tuberculosis and treatment for 6 months 9 | 409
Alzheimer's disease 8 | 658
Atopic dermatitis 8 | 952
Bipolar Disorder 8 | 666
Cataract 8 | 297
Cerebellar Ataxia 8 | 304
Endometrial cancer 8 | 311
Epilepsy 8 | 792
Lens Opacities 8 | 231
Muscle hypotonia 8 | 571
Nystagmus 8 | 317
Obesity 8 | 678
Seizures 8 | 596
hepatocellular carcinoma 8 | 547
pancreatic carcinoma 8 | 562
Amyotrophic lateral sclerosis 7 | 451
Congenital Epicanthus 7 | 177
Nephronophthisis 7 | 80
Neurodegenerative disease 7 | 414
active Crohn's disease 7 | 922
medulloblastoma 7 | 720
primary Sjogren syndrome 7 | 735

Tissue

Endocrine System 277 | 18,159
Female tissues 273 | 17,400
Male tissues 270 | 17,142
Digestive Tract 269 | 17,369
Nervous System 269 | 16,725
Respiratory system 269 | 16,393
Skin and soft tissues 269 | 17,230
Urinary Tract 268 | 16,678
Liver and Pancreas 267 | 16,750
Blood and immune system 263 | 16,909
Cardiovascular System 257 | 15,192

Target Family

Non-IDG 247 | 12,091
Enzyme 23 | 4,145
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400

UniProt Keyword

WD repeat 277 | 277
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability