Development Level

Tbio 100 | 11,445
Tdark 43 | 6,588
Tchem 29 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 8 | 298
abnormal bone structure 6 | 187
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 6 | 278
increased lean body mass 5 | 172
abnormal embryo size 4 | 220
decreased mean corpuscular vol... 4 | 79
increased circulating HDL chol... 4 | 80
increased startle reflex 4 | 112
male infertility 4 | 123
decreased blood urea nitrogen ... 3 | 51
decreased body weight 3 | 161
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating alanine ... 3 | 47
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
hypoactivity 3 | 132
impaired pupillary reflex 3 | 26
increased bone mineral content 3 | 108
increased circulating triglyce... 3 | 42
increased mean corpuscular vol... 3 | 92
increased mean platelet volume 3 | 45
increased total body fat amoun... 3 | 134
short tibia 3 | 97
abnormal coat appearance 2 | 31
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
female infertility 2 | 60
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating creatini... 2 | 38
increased circulating sodium l... 2 | 71
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal vertebrae morphology 1 | 18
absent spleen 1 | 3
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
trunk curl 1 | 16

Disease

Carcinoma 105 | 11,493
osteosarcoma 82 | 7,950
ovarian cancer 81 | 8,520
medulloblastoma, large-cell 48 | 6,241
group 3 medulloblastoma 44 | 4,104
psoriasis 44 | 6,694
atypical teratoid / rhabdoid tumor 42 | 5,112
glioblastoma 42 | 5,792
malignant mesothelioma 39 | 3,232
ependymoma 37 | 4,679
lung cancer 34 | 4,740
Cancer 32 | 2,499
primitive neuroectodermal tumor 32 | 3,035
Breast cancer 31 | 3,578
adult high grade glioma 28 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
invasive ductal carcinoma 22 | 2,951
Intellectual disability 21 | 1,016
Astrocytoma, Pilocytic 20 | 3,081
Kidney cancer 20 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
non-small cell lung cancer 18 | 2,890
oligodendroglioma 18 | 2,850
astrocytic glioma 17 | 2,597
Pick disease 16 | 1,894
pancreatic cancer 15 | 2,398
spina bifida 15 | 1,074
Schizophrenia 14 | 1,160
group 4 medulloblastoma 14 | 1,855
lung adenocarcinoma 14 | 2,716
Breast Neoplasms 13 | 445
subependymal giant cell astrocytoma 13 | 2,287
juvenile dermatomyositis 12 | 1,187
dermatomyositis 11 | 966
lung carcinoma 11 | 2,843
Autosomal recessive predisposition 10 | 1,442
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Global developmental delay 10 | 608
Low intelligence 10 | 645
Mammary Neoplasms 10 | 425
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Multiple myeloma 10 | 1,332
Poor school performance 10 | 645
acute quadriplegic myopathy 10 | 1,158
pituitary cancer 10 | 1,972
Epilepsy 9 | 792
Muscle hypotonia 9 | 571
Rheumatoid arthritis 9 | 1,191
ductal carcinoma in situ 9 | 1,745
hepatocellular carcinoma 9 | 547
Seizures 8 | 596
acute myeloid leukemia 8 | 783
adrenocortical carcinoma 8 | 1,428
gastric cancer 8 | 459
interstitial cystitis 8 | 2,312
pediatric high grade glioma 8 | 1,064
progressive supranuclear palsy 8 | 676
tuberculosis 8 | 2,010
tuberculosis and treatment for 6 months 8 | 409
Liver cancer 7 | 604
Orbital separation excessive 7 | 244
Short stature 7 | 531
Waldenstrons macroglobulinemia 7 | 765
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
non primary Sjogren syndrome sicca 7 | 891
Congenital Epicanthus 6 | 177
Failure to gain weight 6 | 365
Feeding difficulties in infancy 6 | 175
Leukemia, Myelocytic, Acute 6 | 120
Neurodevelopmental Disorders 6 | 70
Pediatric failure to thrive 6 | 365
Small head 6 | 374
breast carcinoma 6 | 1,638
medulloblastoma 6 | 720
Amyotrophic lateral sclerosis 5 | 451
Bipolar Disorder 5 | 666
Bladder Neoplasm 5 | 112
Carcinoma, Hepatocellular 5 | 228
Cerebral atrophy 5 | 178
Delayed speech and language development 5 | 112
Hypoplastic mandible condyle 5 | 275
Immune system cancer 5 | 140
Language Delay 5 | 112
Liver carcinoma 5 | 240
Male infertility 5 | 206
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Prostatic Neoplasms 5 | 495
Speech Delay 5 | 112
Speech impairment 5 | 112
Strabismus 5 | 270
cutaneous lupus erythematosus 5 | 1,057
nasopharyngeal carcinoma 5 | 1,058
primary Sjogren syndrome 5 | 735

Tissue

Endocrine System 168 | 18,159
Liver and Pancreas 166 | 16,750
Nervous System 166 | 16,725
Female tissues 165 | 17,400
Male tissues 165 | 17,142
Skin and soft tissues 165 | 17,230
Cardiovascular System 163 | 15,192
Respiratory system 163 | 16,393
Digestive Tract 162 | 17,369
Urinary Tract 162 | 16,678
Blood and immune system 161 | 16,909

Target Family

Enzyme 102 | 4,145
Epigenetic 44 | 242
TF/Epigenetic 15 | 38
Non-IDG 13 | 12,091
Transporter 1 | 473

UniProt Keyword

S-adenosyl-L-methionine 175 | 175
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability