Development Level

Tbio 245 | 11,178
Tdark 55 | 6,569
Tchem 34 | 1,885
Tclin 4 | 612

IMPC Phenotype

preweaning lethality, complete... 34 | 979
embryonic lethality prior to o... 13 | 239
preweaning lethality, incomple... 13 | 499
abnormal behavior 11 | 298
abnormal embryo size 11 | 220
decreased body weight 10 | 161
embryonic lethality prior to t... 10 | 278
abnormal bone structure 7 | 187
male infertility 7 | 123
embryonic growth retardation 6 | 106
decreased bone mineral density 5 | 126
female infertility 5 | 60
abnormal heart morphology 4 | 162
abnormal neural tube closure 4 | 46
decreased hemoglobin content 4 | 68
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular hem... 4 | 31
decreased vertical activity 4 | 208
enlarged heart 4 | 210
hyperactivity 4 | 148
increased circulating alkaline... 4 | 122
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
increased total body fat amoun... 4 | 134
thrombocytopenia 4 | 56
abnormal embryo turning 3 | 31
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased caudal vertebrae num... 3 | 53
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
decreased lean body mass 3 | 135
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
edema 3 | 59
increased circulating HDL chol... 3 | 80
abnormal bone mineralization 2 | 38
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal pericardium morpholog... 2 | 26
abnormal placenta size 2 | 20
abnormal rib morphology 2 | 10
abnormal spleen morphology 2 | 55
abnormal vertebrae morphology 2 | 18
abnormal vertebral arch morpho... 2 | 9
cataract 2 | 92
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased circulating creatine... 2 | 5
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased thermal nociceptive ... 2 | 9
pale yolk sac 2 | 25
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small kidney 2 | 16
small testis 2 | 58
thrombocytosis 2 | 27
tremors 2 | 39
trunk curl 2 | 16
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal heart left ventricle ... 1 | 16
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
absent spleen 1 | 3
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
increased anti-nuclear antigen... 1 | 19
increased blood uric acid leve... 1 | 5
increased circulating aspartat... 1 | 15
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
prenatal lethality 1 | 28

Disease

Carcinoma 205 | 11,192
ovarian cancer 178 | 8,297
osteosarcoma 165 | 7,766
psoriasis 125 | 6,514
medulloblastoma, large-cell 119 | 6,086
lung cancer 113 | 4,607
glioblastoma 106 | 5,635
group 3 medulloblastoma 104 | 4,002
Breast cancer 97 | 3,469
atypical teratoid / rhabdoid tumor 92 | 4,971
malignant mesothelioma 79 | 3,135
Cancer 78 | 2,388
primitive neuroectodermal tumor 68 | 2,957
non-small cell lung cancer 65 | 2,799
lung adenocarcinoma 62 | 2,627
ependymoma 60 | 4,559
adult high grade glioma 54 | 3,701
invasive ductal carcinoma 53 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,204
breast carcinoma 40 | 1,589
oligodendroglioma 39 | 2,768
colon cancer 37 | 1,428
Kidney cancer 36 | 2,548
pancreatic cancer 36 | 2,322
pituitary cancer 36 | 1,915
group 4 medulloblastoma 34 | 1,806
subependymal giant cell astrocytoma 34 | 2,230
diabetes mellitus 33 | 1,683
astrocytic glioma 32 | 2,530
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,872
adrenocortical carcinoma 31 | 1,385
ductal carcinoma in situ 31 | 1,686
Astrocytoma, Pilocytic 30 | 3,006
Autosomal recessive predisposition 30 | 1,407
tuberculosis 30 | 1,963
Multiple myeloma 28 | 1,296
acute quadriplegic myopathy 28 | 1,133
Pick disease 27 | 1,856
Intellectual disability 26 | 998
Rheumatoid arthritis 26 | 1,156
Schizophrenia 26 | 1,136
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,911
astrocytoma 24 | 1,113
hepatocellular carcinoma 23 | 536
juvenile dermatomyositis 23 | 1,147
lung carcinoma 23 | 2,755
non primary Sjogren syndrome sicca 22 | 861
Waldenstrons macroglobulinemia 21 | 742
dermatomyositis 21 | 941
spina bifida 21 | 1,053
ulcerative colitis 21 | 1,765
Short stature 19 | 514
Small head 19 | 366
gastric cancer 19 | 445
nasopharyngeal carcinoma 19 | 1,024
Endometriosis 18 | 521
acute myeloid leukemia 18 | 760
pancreatic carcinoma 18 | 555
progressive supranuclear palsy 18 | 656
Bipolar Disorder 17 | 646
Xeroderma pigmentosum 17 | 42
cystic fibrosis 17 | 1,629
pediatric high grade glioma 17 | 1,035
tuberculosis and treatment for 6 months 17 | 399
Attention deficit hyperactivity disorder 16 | 272
Cognitive delay 16 | 596
Global developmental delay 16 | 596
Mental and motor retardation 16 | 596
interstitial cystitis 16 | 2,237
medulloblastoma 16 | 702
Alzheimer's disease 15 | 640
Muscle hypotonia 15 | 562
cutaneous lupus erythematosus 15 | 1,016
Atopic dermatitis 14 | 915
Dull intelligence 14 | 634
Low intelligence 14 | 634
Mental Retardation 14 | 634
Mental deficiency 14 | 634
Poor school performance 14 | 634
primary pancreatic ductal adenocarcinoma 14 | 1,071
Cockayne syndrome 13 | 59
Depressive disorder 13 | 401
Failure to gain weight 13 | 359
Pediatric failure to thrive 13 | 359
Prostatic Neoplasms 13 | 472
gastric carcinoma 13 | 781
non-small cell lung carcinoma 13 | 302
Acquired metabolic disease 12 | 329
Epilepsy 12 | 775
Fetal Growth Retardation 12 | 186
Infant, Small for Gestational Age 12 | 174
Intrauterine retardation 12 | 174
Lynch syndrome 12 | 34
Male infertility 12 | 199
Strabismus 12 | 265
aldosterone-producing adenoma 12 | 646
sonic hedgehog group medulloblastoma 12 | 459
Obesity 11 | 655
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 492

Tissue

Endocrine System 321 | 18,159
Female tissues 311 | 17,400
Digestive Tract 310 | 17,369
Skin and soft tissues 310 | 17,230
Nervous System 309 | 16,725
Blood and immune system 308 | 16,909
Male tissues 308 | 17,142
Liver and Pancreas 304 | 16,750
Respiratory system 303 | 16,393
Urinary Tract 303 | 16,678
Cardiovascular System 294 | 15,192

Target Family

Non-IDG 189 | 12,091
Enzyme 69 | 4,145
Transcription Factor 49 | 1,400
Epigenetic 27 | 242
TF/Epigenetic 4 | 38

PANTHER Protein Class (1)

DNA binding protein 338 | 338
RNA binding protein 476 | 476
kinase 357 | 357
protease 224 | 224
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
protease inhibitor 196 | 196
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
transcription cofactor 96 | 96
helix-turn-helix transcription... 87 | 87
ubiquitin-protein ligase 83 | 83
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
zinc finger transcription fact... 50 | 50
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
basic helix-loop-helix transcr... 42 | 42
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
nucleotidyltransferase 20 | 20
transaminase 18 | 18
metalloprotease 16 | 16
carbohydrate transporter 15 | 15
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
basic leucine zipper transcrip... 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
glycosidase 11 | 11
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
phosphodiesterase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
HMG box transcription factor 1 | 1
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability