Development Level

Tbio 204 | 11,445
Tchem 41 | 1,598
Tdark 23 | 6,588
Tclin 10 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

embryonic lethality prior to t... 278 | 278
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 187 | 8,520
Carcinoma 178 | 11,493
osteosarcoma 147 | 7,950
medulloblastoma, large-cell 102 | 6,241
glioblastoma 94 | 5,792
psoriasis 92 | 6,694
atypical teratoid / rhabdoid tumor 86 | 5,112
lung cancer 83 | 4,740
group 3 medulloblastoma 78 | 4,104
Breast cancer 77 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 71 | 3,291
ependymoma 68 | 4,679
Cancer 59 | 2,499
malignant mesothelioma 58 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 56 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,989
non-small cell lung cancer 54 | 2,890
Kidney cancer 52 | 2,613
primitive neuroectodermal tumor 50 | 3,035
adult high grade glioma 47 | 3,801
astrocytic glioma 47 | 2,597
lung adenocarcinoma 46 | 2,716
oligodendroglioma 46 | 2,850
Autosomal recessive predisposition 44 | 1,442
invasive ductal carcinoma 44 | 2,951
Pick disease 42 | 1,894
pancreatic cancer 41 | 2,398
breast carcinoma 39 | 1,638
diabetes mellitus 35 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Astrocytoma, Pilocytic 33 | 3,081
group 4 medulloblastoma 33 | 1,855
lung carcinoma 33 | 2,843
tuberculosis 33 | 2,010
Multiple myeloma 30 | 1,332
adrenocortical carcinoma 30 | 1,428
acute quadriplegic myopathy 29 | 1,158
Intellectual disability 28 | 1,016
ulcerative colitis 27 | 1,819
colon cancer 26 | 1,478
ductal carcinoma in situ 26 | 1,745
interstitial cystitis 26 | 2,312
dermatomyositis 25 | 966
pituitary cancer 25 | 1,972
spina bifida 25 | 1,074
Schizophrenia 24 | 1,160
subependymal giant cell astrocytoma 24 | 2,287
Cognitive delay 23 | 608
Global developmental delay 23 | 608
Mental and motor retardation 23 | 608
acute myeloid leukemia 23 | 783
juvenile dermatomyositis 23 | 1,187
Epilepsy 21 | 792
Seizures 21 | 596
astrocytoma 21 | 1,146
Dull intelligence 20 | 645
Low intelligence 20 | 645
Mental Retardation 20 | 645
Mental deficiency 20 | 645
Poor school performance 20 | 645
Waldenstrons macroglobulinemia 19 | 765
primary pancreatic ductal adenocarcinoma 19 | 1,109
non primary Sjogren syndrome sicca 18 | 891
Muscle hypotonia 17 | 571
Short stature 17 | 531
pediatric high grade glioma 17 | 1,064
Alzheimer's disease 16 | 658
hepatocellular carcinoma 16 | 547
Cerebellar Ataxia 15 | 304
Neurodegenerative disease 15 | 414
Rheumatoid arthritis 15 | 1,191
Breast Neoplasms 14 | 445
Anemia 13 | 365
Bipolar Disorder 13 | 666
Endometriosis 13 | 540
Failure to gain weight 13 | 365
Mammary Neoplasms 13 | 425
Pediatric failure to thrive 13 | 365
Sensorineural Hearing Loss (disorder) 13 | 284
Small head 13 | 374
cutaneous lupus erythematosus 13 | 1,057
cystic fibrosis 13 | 1,696
medulloblastoma 13 | 720
Liver cancer 12 | 604
Melanoma 12 | 711
Obesity 12 | 678
nasopharyngeal carcinoma 12 | 1,058
primary Sjogren syndrome 12 | 735
Atopic dermatitis 11 | 952
Heart disease 11 | 306
Prostatic Neoplasms 11 | 495
Strabismus 11 | 270
esophageal adenocarcinoma 11 | 737
Down syndrome 10 | 499
Muscle Spasticity 10 | 195
Parkinson's disease 10 | 392
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
hereditary spastic paraplegia 10 | 318
tuberculosis and treatment for 6 months 10 | 409
Nystagmus 9 | 317

Tissue

Endocrine System 277 | 18,159
Blood and immune system 276 | 16,909
Digestive Tract 276 | 17,369
Female tissues 276 | 17,400
Male tissues 276 | 17,142
Nervous System 276 | 16,725
Skin and soft tissues 276 | 17,230
Respiratory system 275 | 16,393
Urinary Tract 275 | 16,678
Liver and Pancreas 274 | 16,750
Cardiovascular System 269 | 15,192

Target Family

Non-IDG 132 | 12,091
Enzyme 90 | 4,145
Kinase 17 | 634
Transcription Factor 15 | 1,400
Transporter 7 | 473
Ion Channel 6 | 344
Epigenetic 5 | 242
GPCR 3 | 408
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability