Development Level

Tbio 42 | 11,445
Tchem 15 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal eye anterior chamber ... 2 | 9
decreased bone mineral content 2 | 151
improved glucose tolerance 2 | 79
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 49 | 11,493
ovarian cancer 45 | 8,520
glioblastoma 34 | 5,792
pancreatic cancer 34 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
invasive ductal carcinoma 30 | 2,951
lung cancer 28 | 4,740
Astrocytoma, Pilocytic 27 | 3,081
Cancer 27 | 2,499
osteosarcoma 27 | 7,950
atypical teratoid / rhabdoid tumor 26 | 5,112
medulloblastoma, large-cell 26 | 6,241
psoriasis 26 | 6,694
Breast cancer 25 | 3,578
non-small cell lung cancer 25 | 2,890
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
malignant mesothelioma 23 | 3,232
cystic fibrosis 22 | 1,696
ependymoma 22 | 4,679
lung carcinoma 22 | 2,843
primary pancreatic ductal adenocarcinoma 22 | 1,109
group 3 medulloblastoma 20 | 4,104
lung adenocarcinoma 19 | 2,716
Duchenne muscular dystrophy 18 | 601
breast carcinoma 18 | 1,638
ulcerative colitis 18 | 1,819
Kidney cancer 16 | 2,613
ductal carcinoma in situ 16 | 1,745
interstitial cystitis 16 | 2,312
subependymal giant cell astrocytoma 15 | 2,287
Liver Cirrhosis, Experimental 14 | 769
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
colon cancer 14 | 1,478
diabetes mellitus 14 | 1,728
gastric carcinoma 14 | 807
juvenile dermatomyositis 14 | 1,187
oligodendroglioma 14 | 2,850
adrenocortical carcinoma 13 | 1,428
pituitary cancer 13 | 1,972
Autosomal recessive predisposition 12 | 1,442
astrocytic glioma 11 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
primitive neuroectodermal tumor 11 | 3,035
Kidney disease 10 | 430
limb girdle muscular dystrophy 2A 10 | 213
tuberculosis 10 | 2,010
Atopic dermatitis 9 | 952
acute quadriplegic myopathy 9 | 1,158
esophageal adenocarcinoma 9 | 737
group 4 medulloblastoma 9 | 1,855
primary Sjogren syndrome 9 | 735
active Crohn's disease 8 | 922
interstitial lung disease 8 | 298
nasopharyngeal carcinoma 8 | 1,058
Acquired scoliosis 7 | 281
Atherosclerosis 7 | 291
Becker muscular dystrophy 7 | 191
Curvature of spine 7 | 282
Pick disease 7 | 1,894
Pulmonary Fibrosis 7 | 106
Renal Cell Carcinoma 7 | 214
aldosterone-producing adenoma 7 | 665
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
Alzheimer's disease 6 | 658
Down syndrome 6 | 499
Liver Cirrhosis 6 | 181
Mammary Neoplasms, Experimental 6 | 154
Obesity 6 | 678
Osteoarthritis 6 | 184
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
Vascular disease 6 | 319
astrocytoma 6 | 1,146
fibroadenoma 6 | 559
periodontitis 6 | 293
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Chronic obstructive pulmonary disease 5 | 184
Coronary artery disease 5 | 268
Endometriosis 5 | 540
Hypertensive disease 5 | 292
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Platyspondyly 5 | 56
Proteinuria 5 | 144
Schizophrenia 5 | 1,160
Thrombocytopenia 5 | 197
nephrosclerosis 5 | 333
pediatric high grade glioma 5 | 1,064
urothelial carcinoma 5 | 318
Cerebrovascular disease 4 | 238
Epilepsy 4 | 792
Hypertension 4 | 396
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783

Tissue

Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Male tissues 57 | 17,142
Urinary Tract 57 | 16,678
Blood and immune system 56 | 16,909
Liver and Pancreas 56 | 16,750
Respiratory system 56 | 16,393
Skin and soft tissues 55 | 17,230
Cardiovascular System 54 | 15,192
Nervous System 53 | 16,725

Target Family

Non-IDG 38 | 12,091
Enzyme 12 | 4,145
Transcription Factor 4 | 1,400
Kinase 3 | 634
GPCR 2 | 408

GO Function

collagen binding 59 | 59
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability