Development Level

Tbio 789 | 10,625
Tchem 165 | 1,890
Tdark 114 | 7,003
Tclin 57 | 602

Collection

Ion Channel: IDG Consortium (Targets) 7 | 102
Kinase: IDG Consortium (Targets) 6 | 125
GPCR: IDG Consortium (Targets) 4 | 128
Kinase: IDG Consortium (Complete/Control) 2 | 37
GPCR: IDG Consortium (Complete/Control) 1 | 24

IMPC Phenotype

preweaning lethality, complete... 47 | 633
abnormal behavior 22 | 226
embryonic lethality prior to t... 19 | 187
decreased grip strength 17 | 123
preweaning lethality, incomple... 17 | 260
decreased total body fat amoun... 15 | 186
increased or absent threshold ... 13 | 128
abnormal bone structure 12 | 131
decreased lean body mass 12 | 195
abnormal embryo size 11 | 112
decreased bone mineral content 11 | 157
decreased circulating HDL chol... 11 | 77
increased circulating alkaline... 11 | 119
decreased circulating choleste... 10 | 85
embryonic lethality prior to o... 10 | 148
enlarged heart 10 | 111
short tibia 10 | 82
hypoactivity 9 | 89
increased circulating sodium l... 9 | 71
abnormal coat-hair pigmentatio... 8 | 54
abnormal lens morphology 8 | 73
decreased body length 8 | 108
decreased fasted circulating g... 8 | 49
increased grip strength 8 | 83
abnormal sleep behavior 7 | 63
decreased body weight 7 | 174
decreased circulating LDL chol... 7 | 37
decreased circulating glucose ... 7 | 121
decreased mean corpuscular vol... 7 | 50
increased circulating HDL chol... 7 | 63
increased hematocrit 7 | 36
increased mean corpuscular hem... 7 | 93
abnormal retina morphology 6 | 100
cardiovascular system phenotyp... 6 | 35
decreased circulating insulin ... 6 | 75
decreased mean corpuscular hem... 6 | 34
hyperactivity 6 | 108
increased mean corpuscular vol... 6 | 91
increased total body fat amoun... 6 | 57
tremors 6 | 34
abnormal bone mineralization 5 | 55
abnormal kidney morphology 5 | 30
abnormal retinal pigmentation 5 | 61
cataract 5 | 26
decreased bone mineral density 5 | 126
decreased circulating serum al... 5 | 79
decreased mean corpuscular hem... 5 | 19
decreased prepulse inhibition 5 | 52
decreased vertical activity 5 | 22
improved glucose tolerance 5 | 56
increased body weight 5 | 42
increased circulating choleste... 5 | 53
increased lean body mass 5 | 107
increased mean corpuscular hem... 5 | 25
male infertility 5 | 62
thrombocytopenia 5 | 46
abnormal QRS complex 4 | 25
abnormal behavioral response t... 4 | 52
abnormal epididymis morphology 4 | 31
abnormal facial morphology 4 | 9
abnormal limb bud morphology 4 | 15
abnormal limb morphology 4 | 7
abnormal locomotor activation 4 | 26
abnormal neural tube closure 4 | 37
abnormal retinal blood vessel ... 4 | 18
abnormal seminal vesicle morph... 4 | 47
decreased circulating alkaline... 4 | 41
hydrops fetalis 4 | 22
increased blood urea nitrogen ... 4 | 44
increased bone mineral content 4 | 92
increased circulating chloride... 4 | 43
increased heart weight 4 | 37
increased hemoglobin content 4 | 45
prenatal lethality prior to he... 4 | 64
abnormal body wall morphology 3 | 7
abnormal eye morphology 3 | 38
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
abnormal tail movements 3 | 12
abnormal tooth morphology 3 | 24
cleft palate 3 | 6
decreased circulating bilirubi... 3 | 14
decreased circulating triglyce... 3 | 83
decreased effector memory CD8-... 3 | 24
decreased gamma-delta T cell n... 3 | 18
decreased heart weight 3 | 44
decreased hemoglobin content 3 | 53
decreased neutrophil cell numb... 3 | 37
decreased threshold for audito... 3 | 32
enlarged epididymis 3 | 27
hemorrhage 3 | 12
impaired glucose tolerance 3 | 52
increased circulating free fat... 3 | 17
increased circulating potassiu... 3 | 31
increased circulating triglyce... 3 | 24
increased erythrocyte cell num... 3 | 26
increased fasted circulating g... 3 | 68
increased leukocyte cell numbe... 3 | 37
increased startle reflex 3 | 38
persistence of hyaloid vascula... 3 | 22

Disease

ovarian cancer 553 | 8,491
osteosarcoma 491 | 7,933
psoriasis 476 | 6,685
glioblastoma 446 | 5,572
medulloblastoma, large-cell 425 | 6,234
atypical teratoid / rhabdoid tumor 323 | 4,369
Cancer 319 | 2,346
lung cancer 310 | 4,473
pilocytic astrocytoma 298 | 3,086
lung carcinoma 270 | 2,844
diabetes mellitus 245 | 1,663
pediatric high grade glioma 236 | 2,712
oligodendroglioma 233 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 231 | 3,289
malignant mesothelioma 230 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 229 | 2,956
invasive ductal carcinoma 228 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 220 | 2,988
pancreatic cancer 213 | 2,300
lung adenocarcinoma 210 | 2,714
primitive neuroectodermal tumor 210 | 3,031
Breast cancer 202 | 3,098
non-small cell lung cancer 191 | 2,798
subependymal giant cell astrocytoma 187 | 2,287
ependymoma 178 | 2,514
interstitial cystitis 165 | 2,299
astrocytoma 161 | 1,493
ulcerative colitis 158 | 2,087
Carcinoma 156 | 2,147
Pick disease 156 | 1,893
astrocytic glioma 149 | 2,241
pituitary cancer 149 | 1,972
tuberculosis 144 | 1,563
posterior fossa group A ependymoma 143 | 1,511
Rheumatoid Arthritis 135 | 1,170
cystic fibrosis 131 | 1,670
pancreatic ductal adenocarcinoma liver metastasis 128 | 1,795
Multiple myeloma 127 | 1,327
adult high grade glioma 127 | 2,148
group 4 medulloblastoma 125 | 1,875
ductal carcinoma in situ 124 | 1,745
primary pancreatic ductal adenocarcinoma 119 | 1,271
dermatomyositis 118 | 966
breast carcinoma 117 | 1,614
medulloblastoma 112 | 1,524
group 3 medulloblastoma 108 | 2,254
juvenile dermatomyositis 107 | 1,189
acute quadriplegic myopathy 103 | 1,157
Alzheimer's disease 101 | 644
colon cancer 100 | 1,475
sonic hedgehog group medulloblastoma 100 | 1,482
Arthritis 99 | 248
posterior fossa group B ependymoma 98 | 1,530
adrenocortical carcinoma 97 | 1,427
Kidney disease 96 | 397
cutaneous lupus erythematosus 93 | 1,056
Hypersensitivity reaction type II disease 90 | 235
gastric carcinoma 86 | 832
Duchenne muscular dystrophy 80 | 602
esophageal adenocarcinoma 76 | 737
Schizophrenia 75 | 503
Obesity 74 | 616
atypical teratoid/rhabdoid tumor 74 | 1,095
Ankylosing spondylitis 73 | 138
Waldenstrons macroglobulinemia 73 | 764
active Crohn's disease 70 | 918
spina bifida 70 | 1,064
mucosa-associated lymphoid tissue lymphoma 69 | 480
Uveitis 66 | 103
Acquired immunodeficiency syndrome 65 | 164
Multiple Sclerosis 65 | 498
Juvenile rheumatoid arthritis 64 | 105
pancreatic carcinoma 62 | 567
Atherosclerosis 61 | 275
Human immunodeficiency virus infectious disease 60 | 129
Liver disease 60 | 219
Neurodegenerative disease 60 | 383
Parkinson's disease 60 | 364
Down syndrome 59 | 548
Prostatic Neoplasms 58 | 471
nasopharyngeal carcinoma 58 | 1,056
Anemia 57 | 252
Atopic dermatitis 57 | 944
Behcet's disease 57 | 74
Hypertension 56 | 293
Stevens-Johnson syndrome 54 | 91
non primary Sjogren syndrome sicca 54 | 840
Dermatitis 53 | 141
Epilepsy 53 | 346
Psoriatic arthritis 53 | 85
Vascular disease 51 | 281
Asthma 50 | 349
autosomal dominant Emery-Dreifuss muscular dystrophy 50 | 499
primary Sjogren syndrome 50 | 788
Cerebrovascular disease 49 | 231
Heart disease 47 | 279
acute myeloid leukemia 46 | 785
aldosterone-producing adenoma 46 | 664
Endometriosis 45 | 535
Intellectual disability 44 | 573

Tissue

Nervous System 1,045 | 18,560
Endocrine System 1,044 | 18,511
Digestive Tract 1,043 | 18,472
Female tissues 1,042 | 18,646
Urinary Tract 1,039 | 18,443
Liver and Pancreas 1,037 | 18,135
Cardiovascular System 1,030 | 17,957
Blood and immune system 1,029 | 17,994
Skin and soft tissues 1,028 | 18,114
Male tissues 1,027 | 17,968
Respiratory system 1,018 | 17,483

Target Family

Non-IDG 766 | 11,969
Enzyme 231 | 4,146
Transporter 35 | 473
Kinase 34 | 634
Ion Channel 33 | 341
GPCR 18 | 408
Transcription Factor 5 | 1,400
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

Compartment GO Term

cytoplasmic, membrane-bounded ... 1,125 | 1,125
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability