Development Level

Tbio 3,475 | 11,445
Tdark 1,004 | 6,588
Tchem 491 | 1,598
Tclin 107 | 613

Collection

Kinase: IDG Consortium (Target... 43 | 125
Kinase: IDG Consortium (Comple... 13 | 37
GPCR: IDG Consortium (Targets) 7 | 126
Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 441 | 979
preweaning lethality, incomple... 162 | 499
embryonic lethality prior to t... 121 | 278
embryonic lethality prior to o... 111 | 239
abnormal behavior 99 | 298
abnormal embryo size 93 | 220
decreased total body fat amoun... 69 | 207
decreased body weight 59 | 161
enlarged heart 59 | 210
increased lean body mass 54 | 172
abnormal bone structure 52 | 187
abnormal heart morphology 52 | 162
increased startle reflex 46 | 112
decreased vertical activity 45 | 208
hypoactivity 44 | 132
hyperactivity 43 | 148
decreased lean body mass 40 | 135
increased bone mineral content 40 | 108
increased or absent threshold ... 40 | 101
male infertility 40 | 123
embryonic growth retardation 39 | 106
prenatal lethality prior to he... 39 | 87
decreased circulating glucose ... 38 | 126
decreased body length 37 | 101
decreased grip strength 37 | 116
decreased bone mineral content 36 | 151
decreased bone mineral density 36 | 126
increased circulating alkaline... 35 | 122
increased mean corpuscular hem... 35 | 96
decreased circulating choleste... 34 | 93
increased bone mineral density 34 | 72
increased total body fat amoun... 34 | 134
decreased prepulse inhibition 33 | 82
increased mean corpuscular vol... 33 | 92
cataract 32 | 92
short tibia 30 | 97
abnormal lens morphology 28 | 81
decreased leukocyte cell numbe... 28 | 73
abnormal kidney morphology 27 | 65
decreased circulating triglyce... 26 | 79
abnormal seminal vesicle morph... 25 | 114
decreased circulating serum al... 25 | 82
decreased lymphocyte cell numb... 25 | 83
increased circulating HDL chol... 25 | 80
abnormal retina morphology 24 | 71
abnormal coat-hair pigmentatio... 23 | 64
decreased mean corpuscular vol... 23 | 79
abnormal behavioral response t... 22 | 66
abnormal gait 22 | 69
decreased erythrocyte cell num... 22 | 62
increased circulating choleste... 22 | 66
impaired glucose tolerance 21 | 75
abnormal eye morphology 20 | 68
decreased caudal vertebrae num... 20 | 53
decreased hemoglobin content 20 | 68
decreased startle reflex 20 | 75
abnormal neural tube closure 19 | 46
decreased circulating alkaline... 19 | 46
decreased mean corpuscular hem... 19 | 50
edema 19 | 59
small testis 19 | 58
thrombocytopenia 19 | 56
decreased circulating HDL chol... 18 | 68
female infertility 18 | 60
abnormal skin morphology 17 | 50
abnormal spleen morphology 17 | 55
corneal opacity 17 | 32
small superior vagus ganglion 17 | 74
tremors 17 | 39
decreased blood urea nitrogen ... 16 | 51
decreased circulating total pr... 16 | 49
increased grip strength 16 | 41
abnormal embryo turning 15 | 31
decreased circulating insulin ... 15 | 76
decreased fasted circulating g... 15 | 65
increased circulating chloride... 15 | 41
increased circulating sodium l... 15 | 71
increased fasted circulating g... 15 | 76
increased hemoglobin content 15 | 45
increased lymphocyte cell numb... 15 | 32
increased mean platelet volume 15 | 45
increased monocyte cell number 15 | 63
increased neutrophil cell numb... 15 | 46
abnormal sleep behavior 14 | 70
decreased circulating LDL chol... 14 | 38
decreased circulating alanine ... 14 | 47
decreased heart left ventricle... 14 | 28
decreased hematocrit 14 | 46
decreased neutrophil cell numb... 14 | 42
increased blood urea nitrogen ... 14 | 48
increased heart weight 14 | 62
long tibia 14 | 25
abnormal craniofacial morpholo... 13 | 33
hydrometra 13 | 53
improved glucose tolerance 13 | 79
increased circulating creatini... 13 | 38
increased circulating triglyce... 13 | 42
pallor 13 | 34
abnormal bone mineralization 12 | 38
anophthalmia 12 | 33

Disease

Carcinoma 3,290 | 11,493
ovarian cancer 2,863 | 8,520
osteosarcoma 2,549 | 7,950
medulloblastoma, large-cell 1,861 | 6,241
psoriasis 1,832 | 6,694
glioblastoma 1,735 | 5,792
lung cancer 1,559 | 4,740
atypical teratoid / rhabdoid tumor 1,501 | 5,112
group 3 medulloblastoma 1,421 | 4,104
ependymoma 1,259 | 4,679
malignant mesothelioma 1,131 | 3,232
Breast cancer 1,127 | 3,578
adult high grade glioma 1,008 | 3,801
primitive neuroectodermal tumor 969 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 962 | 3,291
Cancer 951 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 870 | 2,989
oligodendroglioma 853 | 2,850
non-small cell lung cancer 827 | 2,890
invasive ductal carcinoma 823 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 821 | 2,955
Kidney cancer 809 | 2,613
astrocytic glioma 747 | 2,597
lung adenocarcinoma 735 | 2,716
Astrocytoma, Pilocytic 701 | 3,081
pancreatic cancer 662 | 2,398
subependymal giant cell astrocytoma 615 | 2,287
Pick disease 596 | 1,894
lung carcinoma 596 | 2,843
tuberculosis 555 | 2,010
group 4 medulloblastoma 550 | 1,855
Multiple myeloma 526 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 523 | 1,962
pituitary cancer 511 | 1,972
interstitial cystitis 509 | 2,312
breast carcinoma 487 | 1,638
ductal carcinoma in situ 479 | 1,745
adrenocortical carcinoma 463 | 1,428
colon cancer 444 | 1,478
acute quadriplegic myopathy 438 | 1,158
diabetes mellitus 435 | 1,728
ulcerative colitis 433 | 1,819
juvenile dermatomyositis 414 | 1,187
astrocytoma 409 | 1,146
cystic fibrosis 395 | 1,696
Rheumatoid arthritis 393 | 1,191
Intellectual disability 377 | 1,016
dermatomyositis 364 | 966
pediatric high grade glioma 347 | 1,064
spina bifida 345 | 1,074
Autosomal recessive predisposition 343 | 1,442
Waldenstrons macroglobulinemia 341 | 765
primary pancreatic ductal adenocarcinoma 325 | 1,109
acute myeloid leukemia 314 | 783
nasopharyngeal carcinoma 301 | 1,058
Schizophrenia 297 | 1,160
cutaneous lupus erythematosus 250 | 1,057
non primary Sjogren syndrome sicca 249 | 891
progressive supranuclear palsy 249 | 676
Atopic dermatitis 241 | 952
Dull intelligence 236 | 645
Low intelligence 236 | 645
Mental Retardation 236 | 645
Mental deficiency 236 | 645
Poor school performance 236 | 645
Short stature 224 | 531
primary Sjogren syndrome 224 | 735
Cognitive delay 219 | 608
Global developmental delay 219 | 608
Mental and motor retardation 219 | 608
medulloblastoma 217 | 720
aldosterone-producing adenoma 215 | 665
active Crohn's disease 211 | 922
Epilepsy 198 | 792
Liver Cirrhosis, Experimental 197 | 769
Breast Neoplasms 196 | 445
gastric carcinoma 194 | 807
Mammary Neoplasms 186 | 425
hepatocellular carcinoma 186 | 547
active ulcerative colitis 185 | 764
esophageal adenocarcinoma 185 | 737
Muscle hypotonia 183 | 571
Endometriosis 181 | 540
Alzheimer's disease 175 | 658
Bipolar Disorder 175 | 666
Obesity 173 | 678
Small head 171 | 374
Prostatic Neoplasms 167 | 495
pancreatic carcinoma 167 | 562
Seizures 166 | 596
Amyotrophic lateral sclerosis 164 | 451
Liver cancer 164 | 604
Melanoma 162 | 711
tuberculosis and treatment for 6 months 160 | 409
sonic hedgehog group medulloblastoma 147 | 467
gastric cancer 146 | 459
autosomal dominant Emery-Dreifuss muscular dystrophy 140 | 510
Cryptorchidism 135 | 296
Down syndrome 134 | 499
Duchenne muscular dystrophy 128 | 601

Tissue

Endocrine System 5,010 | 18,159
Digestive Tract 4,979 | 17,369
Female tissues 4,965 | 17,400
Skin and soft tissues 4,964 | 17,230
Male tissues 4,959 | 17,142
Blood and immune system 4,919 | 16,909
Urinary Tract 4,916 | 16,678
Liver and Pancreas 4,914 | 16,750
Nervous System 4,904 | 16,725
Respiratory system 4,891 | 16,393
Cardiovascular System 4,737 | 15,192

Target Family

Non-IDG 2,731 | 12,091
Enzyme 1,072 | 4,145
Transcription Factor 689 | 1,400
Kinase 224 | 634
Epigenetic 188 | 242
Transporter 52 | 473
Nuclear Receptor 47 | 48
TF/Epigenetic 32 | 38
GPCR 23 | 408
Ion Channel 19 | 344

Compartment GO Term

Nucleoplasm 5,077 | 5,077
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apoptotic chromatin condensation inducer in the nucleus ACIN1 Tbio Non-IDG -1.51987 31.1 429
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
ETS-related transcription factor Elf-5 ELF5 Tbio Transcription Factor -1.72839 58.0 200
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
GATOR complex protein MIOS MIOS Tdark Non-IDG -1.44864 28.1 21
Zinc finger protein 606 ZNF606 Tdark Transcription Factor -0.09691 1.66 101
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Transcription factor-like 5 protein TCFL5 Tbio Transcription Factor -2.62447 404.7 161