Development Level

Tbio 291 | 11,445
Tchem 59 | 1,598
Tclin 19 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 48 | 979
embryonic lethality prior to t... 13 | 278
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to o... 11 | 239
impaired glucose tolerance 8 | 75
abnormal embryo size 7 | 220
abnormal behavior 6 | 298
decreased body weight 6 | 161
enlarged heart 6 | 210
increased bone mineral density 6 | 72
cataract 5 | 92
decreased vertical activity 5 | 208
increased circulating alkaline... 5 | 122
prenatal lethality prior to he... 5 | 87
abnormal bone structure 4 | 187
abnormal seminal vesicle morph... 4 | 114
cardiovascular system phenotyp... 4 | 36
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased fasted circulating g... 4 | 65
decreased startle reflex 4 | 75
decreased total body fat amoun... 4 | 207
embryonic growth retardation 4 | 106
enlarged lymph nodes 4 | 37
hyperactivity 4 | 148
increased bone mineral content 4 | 108
increased mean corpuscular hem... 4 | 96
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
male infertility 4 | 123
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
abnormal retina morphology 3 | 71
abnormal vitreous body morphol... 3 | 10
decreased body length 3 | 101
decreased circulating HDL chol... 3 | 68
decreased circulating aspartat... 3 | 34
decreased circulating choleste... 3 | 93
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased mean corpuscular hem... 3 | 50
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
limb grasping 3 | 41
abnormal bone mineralization 2 | 38
abnormal coat-hair pigmentatio... 2 | 64
abnormal craniofacial morpholo... 2 | 33
abnormal epididymis morphology 2 | 42
abnormal neural tube closure 2 | 46
abnormal spleen morphology 2 | 55
abnormal startle reflex 2 | 15
anophthalmia 2 | 33
decreased basophil cell number 2 | 16
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating serum al... 2 | 82
decreased heart rate 2 | 18
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
enlarged spleen 2 | 41
increased body length 2 | 32
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased heart weight 2 | 62
mammalian phenotype 2 | 17
microphthalmia 2 | 26
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased eosinophil cell numb... 1 | 24
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating iron lev... 1 | 30
iris synechia 1 | 3
long tibia 1 | 25

Disease

Small head 374 | 374
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 372 | 18,159
Digestive Tract 369 | 17,369
Skin and soft tissues 369 | 17,230
Blood and immune system 368 | 16,909
Female tissues 367 | 17,400
Liver and Pancreas 366 | 16,750
Male tissues 366 | 17,142
Nervous System 366 | 16,725
Respiratory system 364 | 16,393
Urinary Tract 364 | 16,678
Cardiovascular System 355 | 15,192

Target Family

Non-IDG 181 | 12,091
Enzyme 99 | 4,145
Transcription Factor 36 | 1,400
Kinase 27 | 634
Transporter 11 | 473
Epigenetic 10 | 242
Ion Channel 7 | 344
TF/Epigenetic 2 | 38
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability