Development Level

Tbio 819 | 11,445
Tchem 184 | 1,598
Tdark 127 | 6,588
Tclin 61 | 613

Collection

Kinase: IDG Consortium (Comple... 8 | 37
Kinase: IDG Consortium (Target... 7 | 125
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 71 | 979
preweaning lethality, incomple... 47 | 499
enlarged heart 24 | 210
abnormal behavior 22 | 298
abnormal bone structure 21 | 187
decreased total body fat amoun... 21 | 207
abnormal embryo size 19 | 220
decreased bone mineral content 19 | 151
decreased bone mineral density 19 | 126
abnormal heart morphology 17 | 162
decreased lean body mass 17 | 135
decreased vertical activity 15 | 208
embryonic lethality prior to o... 15 | 239
embryonic lethality prior to t... 15 | 278
increased lean body mass 14 | 172
increased total body fat amoun... 14 | 134
abnormal seminal vesicle morph... 13 | 114
decreased body weight 13 | 161
decreased circulating glucose ... 13 | 126
hypoactivity 13 | 132
decreased mean corpuscular vol... 12 | 79
decreased body length 11 | 101
hyperactivity 11 | 148
increased bone mineral density 11 | 72
short tibia 11 | 97
decreased circulating HDL chol... 10 | 68
small superior vagus ganglion 10 | 74
decreased circulating choleste... 9 | 93
decreased circulating triglyce... 9 | 79
male infertility 9 | 123
decreased circulating serum al... 8 | 82
embryonic growth retardation 8 | 106
increased bone mineral content 8 | 108
increased circulating alkaline... 8 | 122
abnormal eye morphology 7 | 68
abnormal skin morphology 7 | 50
decreased caudal vertebrae num... 7 | 53
decreased grip strength 7 | 116
decreased lymphocyte cell numb... 7 | 83
increased mean corpuscular vol... 7 | 92
small testis 7 | 58
thrombocytopenia 7 | 56
abnormal lung morphology 6 | 26
abnormal neural tube closure 6 | 46
abnormal retina morphology 6 | 71
decreased leukocyte cell numbe... 6 | 73
decreased mean corpuscular hem... 6 | 50
enlarged spleen 6 | 41
female infertility 6 | 60
impaired glucose tolerance 6 | 75
improved glucose tolerance 6 | 79
increased mean corpuscular hem... 6 | 96
increased neutrophil cell numb... 6 | 46
increased or absent threshold ... 6 | 101
prenatal lethality prior to he... 6 | 87
tremors 6 | 39
abnormal coat-hair pigmentatio... 5 | 64
abnormal gait 5 | 69
abnormal lens morphology 5 | 81
abnormal spleen morphology 5 | 55
abnormal testis morphology 5 | 43
anophthalmia 5 | 33
cataract 5 | 92
corneal opacity 5 | 32
decreased blood urea nitrogen ... 5 | 51
decreased circulating alanine ... 5 | 47
decreased circulating total pr... 5 | 49
decreased mean corpuscular hem... 5 | 31
edema 5 | 59
impaired pupillary reflex 5 | 26
increased blood urea nitrogen ... 5 | 48
increased circulating HDL chol... 5 | 80
increased lymphocyte cell numb... 5 | 32
increased mean corpuscular hem... 5 | 36
increased mean platelet volume 5 | 45
increased red blood cell distr... 5 | 34
abnormal bone mineralization 4 | 38
abnormal epididymis morphology 4 | 42
abnormal facial morphology 4 | 17
abnormal forebrain development 4 | 20
abnormal locomotor behavior 4 | 24
abnormal sleep behavior 4 | 70
decreased T cell number 4 | 15
decreased circulating alkaline... 4 | 46
decreased circulating insulin ... 4 | 76
decreased erythrocyte cell num... 4 | 62
decreased fasted circulating g... 4 | 65
enlarged epididymis 4 | 31
impaired righting response 4 | 26
increased body length 4 | 32
increased circulating chloride... 4 | 41
increased circulating choleste... 4 | 66
increased circulating sodium l... 4 | 71
increased circulating triglyce... 4 | 42
increased hematocrit 4 | 46
increased hemoglobin content 4 | 45
increased leukocyte cell numbe... 4 | 47
limb grasping 4 | 41
pale yolk sac 4 | 25
small thymus 4 | 16

Disease

Rheumatoid arthritis 1,191 | 1,191
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 1,124 | 17,369
Endocrine System 1,121 | 18,159
Female tissues 1,116 | 17,400
Skin and soft tissues 1,114 | 17,230
Urinary Tract 1,114 | 16,678
Male tissues 1,109 | 17,142
Blood and immune system 1,106 | 16,909
Liver and Pancreas 1,101 | 16,750
Respiratory system 1,093 | 16,393
Nervous System 1,087 | 16,725
Cardiovascular System 1,055 | 15,192

Target Family

Non-IDG 686 | 12,091
Enzyme 234 | 4,145
Transcription Factor 97 | 1,400
Kinase 58 | 634
Transporter 40 | 473
Epigenetic 29 | 242
GPCR 19 | 408
Ion Channel 10 | 344
TF/Epigenetic 10 | 38
Nuclear Receptor 4 | 48
oGPCR 4 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
Midnolin MIDN Tbio Non-IDG -1.20798 14.4 87
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon AGPAT5 Tbio Enzyme -0.79526 4.42 180
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275