Development Level

Tbio 328 | 11,651
Tchem 109 | 1,388
Tclin 46 | 612
Tdark 12 | 6,593

Collection

Kinase: IDG Consortium (Comple... 3 | 37
Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 30 | 979
preweaning lethality, incomple... 21 | 499
abnormal behavior 12 | 298
embryonic lethality prior to t... 11 | 278
abnormal embryo size 10 | 220
decreased vertical activity 10 | 208
enlarged heart 9 | 210
embryonic growth retardation 8 | 106
abnormal heart morphology 7 | 162
decreased bone mineral content 7 | 151
decreased lean body mass 7 | 135
hyperactivity 7 | 148
abnormal bone structure 6 | 187
abnormal seminal vesicle morph... 6 | 114
decreased bone mineral density 6 | 126
embryonic lethality prior to o... 6 | 239
hypoactivity 6 | 132
impaired glucose tolerance 6 | 75
increased circulating alkaline... 6 | 122
increased total body fat amoun... 6 | 134
abnormal retina morphology 5 | 71
abnormal spleen morphology 5 | 55
decreased circulating glucose ... 5 | 126
decreased total body fat amoun... 5 | 207
increased lean body mass 5 | 172
short tibia 5 | 97
small testis 5 | 58
abnormal eye morphology 4 | 68
abnormal sleep behavior 4 | 70
abnormal testis morphology 4 | 43
decreased body length 4 | 101
decreased circulating choleste... 4 | 93
decreased grip strength 4 | 116
decreased startle reflex 4 | 75
increased fasted circulating g... 4 | 76
increased startle reflex 4 | 112
small superior vagus ganglion 4 | 74
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal head morphology 3 | 10
abnormal lens morphology 3 | 81
abnormal lung morphology 3 | 26
abnormal tibia morphology 3 | 14
decreased body weight 3 | 161
decreased circulating HDL chol... 3 | 68
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased exploration in new e... 3 | 11
decreased fasted circulating g... 3 | 65
decreased heart weight 3 | 27
decreased hemoglobin content 3 | 68
decreased lymphocyte cell numb... 3 | 83
hydrometra 3 | 53
improved glucose tolerance 3 | 79
increased mean corpuscular vol... 3 | 92
limb grasping 3 | 41
male infertility 3 | 123
persistence of hyaloid vascula... 3 | 33
prenatal lethality prior to he... 3 | 87
abnormal brain morphology 2 | 13
abnormal cornea morphology 2 | 31
abnormal digit morphology 2 | 10
abnormal epididymis morphology 2 | 42
abnormal heart left ventricle ... 2 | 16
abnormal optic disc morphology 2 | 10
abnormal vocalization 2 | 21
cataract 2 | 92
decreased circulating alkaline... 2 | 46
decreased circulating bilirubi... 2 | 19
decreased circulating creatini... 2 | 39
decreased circulating magnesiu... 2 | 13
decreased circulating phosphat... 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
enlarged epididymis 2 | 31
enlarged spleen 2 | 41
enlarged uterus 2 | 11
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral content 2 | 108
increased caudal vertebrae num... 2 | 7
increased circulating HDL chol... 2 | 80
increased circulating alanine ... 2 | 13
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
prolonged ST segment 2 | 36
small seminal vesicle 2 | 10
thrombocytopenia 2 | 56
tremors 2 | 39

Disease

Prostatic Neoplasms 495 | 495
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 485 | 18,159
Digestive Tract 482 | 17,369
Male tissues 482 | 17,142
Female tissues 481 | 17,400
Skin and soft tissues 477 | 17,230
Liver and Pancreas 476 | 16,750
Urinary Tract 473 | 16,678
Blood and immune system 472 | 16,909
Nervous System 468 | 16,725
Respiratory system 468 | 16,393
Cardiovascular System 435 | 15,192

Target Family

Non-IDG 246 | 12,091
Enzyme 143 | 4,145
Transcription Factor 44 | 1,400
Kinase 30 | 634
Epigenetic 9 | 242
Transporter 9 | 473
Nuclear Receptor 7 | 48
GPCR 4 | 408
Ion Channel 2 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability