Development Level

Tbio 10,378 | 11,445
Tdark 4,189 | 6,588
Tchem 1,489 | 1,598
Tclin 574 | 613

Collection

RFA-RM-18-021 278 | 328
Kinase: IDG Consortium (Target... 115 | 125
Ion Channel: IDG Consortium (T... 89 | 99
GPCR: IDG Consortium (Targets) 82 | 126
Kinase: IDG Consortium (Comple... 35 | 37
GPCR: IDG Consortium (Complete... 22 | 25

IMPC Phenotype

preweaning lethality, complete... 956 | 979
preweaning lethality, incomple... 479 | 499
abnormal behavior 283 | 298
embryonic lethality prior to t... 275 | 278
embryonic lethality prior to o... 237 | 239
abnormal embryo size 215 | 220
decreased total body fat amoun... 198 | 207
enlarged heart 189 | 210
decreased vertical activity 185 | 208
abnormal bone structure 174 | 187
increased lean body mass 162 | 172
decreased body weight 155 | 161
abnormal heart morphology 147 | 162
hyperactivity 142 | 148
decreased bone mineral content 141 | 151
decreased lean body mass 129 | 135
increased total body fat amoun... 124 | 134
hypoactivity 122 | 132
decreased bone mineral density 118 | 126
decreased circulating glucose ... 116 | 126
increased circulating alkaline... 111 | 122
male infertility 110 | 123
decreased grip strength 107 | 116
increased startle reflex 105 | 112
abnormal seminal vesicle morph... 103 | 114
embryonic growth retardation 103 | 106
increased bone mineral content 100 | 108
decreased body length 94 | 101
increased or absent threshold ... 94 | 101
short tibia 94 | 97
increased mean corpuscular vol... 91 | 92
increased mean corpuscular hem... 90 | 96
decreased circulating choleste... 89 | 93
cataract 86 | 92
prenatal lethality prior to he... 85 | 87
decreased lymphocyte cell numb... 79 | 83
decreased circulating serum al... 76 | 82
decreased prepulse inhibition 76 | 82
abnormal lens morphology 75 | 81
decreased circulating triglyce... 75 | 79
decreased mean corpuscular vol... 74 | 79
decreased startle reflex 73 | 75
increased fasted circulating g... 72 | 76
increased bone mineral density 71 | 72
improved glucose tolerance 70 | 79
decreased leukocyte cell numbe... 69 | 73
increased circulating HDL chol... 69 | 80
small superior vagus ganglion 69 | 74
decreased circulating insulin ... 68 | 76
abnormal eye morphology 67 | 68
abnormal retina morphology 67 | 71
impaired glucose tolerance 67 | 75
decreased circulating HDL chol... 65 | 68
abnormal sleep behavior 64 | 70
increased circulating sodium l... 64 | 71
abnormal gait 63 | 69
decreased hemoglobin content 62 | 68
abnormal behavioral response t... 61 | 66
abnormal kidney morphology 61 | 65
abnormal coat-hair pigmentatio... 60 | 64
decreased fasted circulating g... 60 | 65
increased circulating choleste... 60 | 66
decreased erythrocyte cell num... 59 | 62
edema 58 | 59
increased monocyte cell number 58 | 63
increased heart weight 55 | 62
small testis 54 | 58
abnormal spleen morphology 52 | 55
decreased caudal vertebrae num... 52 | 53
female infertility 52 | 60
thrombocytopenia 51 | 56
abnormal skin morphology 48 | 50
decreased circulating total pr... 48 | 49
decreased blood urea nitrogen ... 47 | 51
decreased mean corpuscular hem... 46 | 50
hydrometra 46 | 53
increased blood urea nitrogen ... 46 | 48
abnormal neural tube closure 45 | 46
decreased circulating alanine ... 45 | 47
increased leukocyte cell numbe... 45 | 47
increased neutrophil cell numb... 45 | 46
decreased circulating alkaline... 43 | 46
decreased hematocrit 43 | 46
abnormal testis morphology 42 | 43
increased hematocrit 41 | 46
abnormal epididymis morphology 40 | 42
enlarged spleen 40 | 41
increased circulating triglyce... 40 | 42
decreased neutrophil cell numb... 39 | 42
increased hemoglobin content 39 | 45
increased mean platelet volume 39 | 45
limb grasping 39 | 41
decreased red blood cell distr... 38 | 41
abnormal bone mineralization 37 | 38
decreased circulating LDL chol... 37 | 38
increased circulating chloride... 37 | 41
increased circulating creatini... 36 | 38
increased erythrocyte cell num... 36 | 39
prolonged QT interval 36 | 38
tremors 36 | 39

Disease

Carcinoma 10,158 | 11,493
ovarian cancer 8,202 | 8,520
osteosarcoma 7,527 | 7,950
medulloblastoma, large-cell 5,982 | 6,241
psoriasis 5,916 | 6,694
glioblastoma 5,685 | 5,792
atypical teratoid / rhabdoid tumor 5,001 | 5,112
ependymoma 4,617 | 4,679
lung cancer 4,517 | 4,740
group 3 medulloblastoma 4,021 | 4,104
adult high grade glioma 3,679 | 3,801
Breast cancer 3,428 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,192 | 3,291
malignant mesothelioma 3,128 | 3,232
Astrocytoma, Pilocytic 3,049 | 3,081
primitive neuroectodermal tumor 3,002 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,900 | 2,989
invasive ductal carcinoma 2,883 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 2,862 | 2,955
oligodendroglioma 2,827 | 2,850
non-small cell lung cancer 2,789 | 2,890
lung carcinoma 2,729 | 2,843
lung adenocarcinoma 2,585 | 2,716
astrocytic glioma 2,574 | 2,597
Kidney cancer 2,419 | 2,613
pancreatic cancer 2,283 | 2,398
Cancer 2,253 | 2,499
subependymal giant cell astrocytoma 2,252 | 2,287
interstitial cystitis 2,183 | 2,312
pituitary cancer 1,919 | 1,972
tuberculosis 1,909 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 1,888 | 1,962
Pick disease 1,881 | 1,894
group 4 medulloblastoma 1,825 | 1,855
ulcerative colitis 1,724 | 1,819
ductal carcinoma in situ 1,692 | 1,745
cystic fibrosis 1,615 | 1,696
breast carcinoma 1,581 | 1,638
colon cancer 1,414 | 1,478
adrenocortical carcinoma 1,404 | 1,428
diabetes mellitus 1,378 | 1,728
Autosomal recessive predisposition 1,334 | 1,442
Multiple myeloma 1,307 | 1,332
juvenile dermatomyositis 1,161 | 1,187
acute quadriplegic myopathy 1,139 | 1,158
astrocytoma 1,132 | 1,146
primary pancreatic ductal adenocarcinoma 1,089 | 1,109
Rheumatoid arthritis 1,085 | 1,191
Schizophrenia 1,067 | 1,160
pediatric high grade glioma 1,052 | 1,064
spina bifida 1,029 | 1,074
cutaneous lupus erythematosus 994 | 1,057
nasopharyngeal carcinoma 993 | 1,058
Intellectual disability 986 | 1,016
dermatomyositis 917 | 966
active Crohn's disease 879 | 922
Atopic dermatitis 858 | 952
non primary Sjogren syndrome sicca 832 | 891
gastric carcinoma 780 | 807
acute myeloid leukemia 770 | 783
Epilepsy 764 | 792
Waldenstrons macroglobulinemia 754 | 765
Liver Cirrhosis, Experimental 736 | 769
active ulcerative colitis 720 | 764
primary Sjogren syndrome 704 | 735
medulloblastoma 698 | 720
esophageal adenocarcinoma 687 | 737
progressive supranuclear palsy 666 | 676
aldosterone-producing adenoma 654 | 665
Dull intelligence 627 | 645
Low intelligence 627 | 645
Mental Retardation 627 | 645
Mental deficiency 627 | 645
Poor school performance 627 | 645
Alzheimer's disease 623 | 658
Bipolar Disorder 623 | 666
Obesity 618 | 678
Melanoma 603 | 711
Cognitive delay 594 | 608
Global developmental delay 594 | 608
Mental and motor retardation 594 | 608
Duchenne muscular dystrophy 580 | 601
Seizures 576 | 596
Muscle hypotonia 555 | 571
Liver cancer 545 | 604
pancreatic carcinoma 544 | 562
fibroadenoma 543 | 559
hepatocellular carcinoma 535 | 547
Endometriosis 518 | 540
Short stature 503 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 501 | 510
chronic rhinosinusitis 487 | 512
Down syndrome 486 | 499
Prostatic Neoplasms 468 | 495
Multiple Sclerosis 465 | 540
posterior fossa group A ependymoma 455 | 468
sonic hedgehog group medulloblastoma 455 | 467
gastric cancer 449 | 459
mucosa-associated lymphoid tissue lymphoma 446 | 484
Amyotrophic lateral sclerosis 439 | 451

Tissue

Nervous System 16,630 | 16,725
Endocrine System 16,556 | 18,159
Female tissues 16,332 | 17,400
Digestive Tract 16,321 | 17,369
Skin and soft tissues 16,252 | 17,230
Male tissues 16,197 | 17,142
Blood and immune system 16,054 | 16,909
Liver and Pancreas 15,994 | 16,750
Urinary Tract 15,962 | 16,678
Respiratory system 15,773 | 16,393
Cardiovascular System 14,876 | 15,192

Target Family

Non-IDG 9,625 | 12,091
Enzyme 3,784 | 4,145
Transcription Factor 1,230 | 1,400
Kinase 601 | 634
Transporter 421 | 473
GPCR 319 | 408
Ion Channel 311 | 344
Epigenetic 231 | 242
Nuclear Receptor 44 | 48
TF/Epigenetic 37 | 38
oGPCR 27 | 421

HPA RNA Tissue

cerebral cortex 16,630 | 16,630
testis 17,936 | 17,936
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
pancreas 14,070 | 14,070
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability