Development Level

Tbio 50 | 11,445
Tchem 25 | 1,598
Tclin 6 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 6 | 499
decreased bone mineral content 5 | 151
embryonic lethality prior to o... 5 | 239
increased circulating alkaline... 4 | 122
decreased body weight 3 | 161
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
hypoactivity 2 | 132
impaired righting response 2 | 26
increased body length 2 | 32
increased circulating glucose ... 2 | 24
increased circulating total pr... 2 | 28
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased startle reflex 2 | 112
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased fluid intake 1 | 3
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
kinked tail 1 | 2
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 50 | 11,493
ovarian cancer 45 | 8,520
Cancer 44 | 2,499
osteosarcoma 40 | 7,950
lung cancer 33 | 4,740
psoriasis 31 | 6,694
glioblastoma 30 | 5,792
medulloblastoma, large-cell 27 | 6,241
Breast cancer 24 | 3,578
ependymoma 23 | 4,679
atypical teratoid / rhabdoid tumor 21 | 5,112
diabetes mellitus 20 | 1,728
Astrocytoma, Pilocytic 18 | 3,081
malignant mesothelioma 18 | 3,232
pancreatic cancer 18 | 2,398
Kidney cancer 17 | 2,613
lung adenocarcinoma 17 | 2,716
non-small cell lung cancer 17 | 2,890
group 3 medulloblastoma 16 | 4,104
invasive ductal carcinoma 16 | 2,951
lung carcinoma 16 | 2,843
Schizophrenia 15 | 1,160
interstitial cystitis 15 | 2,312
breast carcinoma 14 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
tuberculosis 14 | 2,010
colon cancer 13 | 1,478
group 4 medulloblastoma 13 | 1,855
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
subependymal giant cell astrocytoma 12 | 2,287
adult high grade glioma 11 | 3,801
oligodendroglioma 11 | 2,850
Breast Neoplasms 10 | 445
Multiple myeloma 10 | 1,332
Rheumatoid arthritis 10 | 1,191
acute quadriplegic myopathy 10 | 1,158
cutaneous lupus erythematosus 10 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primitive neuroectodermal tumor 10 | 3,035
Autosomal recessive predisposition 9 | 1,442
Hypertensive disease 9 | 292
Intellectual disability 9 | 1,016
Mammary Neoplasms 9 | 425
astrocytic glioma 9 | 2,597
pediatric high grade glioma 9 | 1,064
ulcerative colitis 9 | 1,819
Depressive disorder 8 | 409
Hypertension 8 | 396
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
Pick disease 8 | 1,894
Prostatic Neoplasms 8 | 495
pituitary cancer 8 | 1,972
Adenoma 7 | 167
Alzheimer's disease 7 | 658
Asthma 7 | 385
Bipolar Disorder 7 | 666
Liver Cirrhosis 7 | 181
Obesity 7 | 678
Vascular disease 7 | 319
primary pancreatic ductal adenocarcinoma 7 | 1,109
Atopic dermatitis 6 | 952
Colonic Neoplasms 6 | 142
Colorectal Neoplasms 6 | 243
Diarrhea 6 | 253
Heart disease 6 | 306
Lung disease 6 | 142
sarcoidosis 6 | 370
Acquired scoliosis 5 | 281
Anemia 5 | 365
Carcinoma, Hepatocellular 5 | 228
Coronary artery disease 5 | 268
Curvature of spine 5 | 282
Disease Models, Animal 5 | 155
Dull intelligence 5 | 645
Endometriosis 5 | 540
Epilepsy 5 | 792
Heart failure 5 | 162
Hypersensitivity reaction type II disease 5 | 253
Liver carcinoma 5 | 240
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mental Depression 5 | 333
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Neoplasm Invasiveness 5 | 161
Neoplasm Metastasis 5 | 168
Neuropathy 5 | 261
Polycystic ovary syndrome 5 | 360
Poor school performance 5 | 645
active Crohn's disease 5 | 922
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
nasopharyngeal carcinoma 5 | 1,058
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074

Tissue

Skin and soft tissues 83 | 17,230
Digestive Tract 81 | 17,369
Endocrine System 81 | 18,159
Blood and immune system 80 | 16,909
Male tissues 80 | 17,142
Nervous System 80 | 16,725
Urinary Tract 80 | 16,678
Female tissues 79 | 17,400
Liver and Pancreas 79 | 16,750
Respiratory system 77 | 16,393
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 23 | 4,145
Kinase 11 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Transcription Factor 2 | 1,400

GO Process

positive regulation of cell gr... 83 | 83
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HemK methyltransferase family member 2 N6AMT1 Tbio Enzyme -1.22424 17.1 138
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718
CDKN2A-interacting protein CDKN2AIP Tbio Non-IDG -0.74312 7.49 147
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Sphingosine kinase 1 SPHK1 Tchem Kinase -2.72994 583.6 518