Development Level

Tbio 31 | 10,625
Tclin 16 | 602
Tchem 15 | 1,890
Tdark 1 | 7,003

IMPC Term

decreased leukocyte cell numbe... 2 | 54
decreased startle reflex 2 | 48
enlarged heart 2 | 111
increased circulating alkaline... 2 | 119
preweaning lethality, complete... 2 | 633
abnormal behavioral response t... 1 | 52
abnormal heart morphology 1 | 51
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
aorta dilation 1 | 3
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 174
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
oligodactyly 1 | 14
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 35 | 8,484
medulloblastoma, large-cell 32 | 6,234
psoriasis 29 | 6,685
glioblastoma 28 | 5,572
lung cancer 28 | 4,466
Cancer 25 | 2,346
osteosarcoma 25 | 7,933
invasive ductal carcinoma 24 | 2,950
non-small cell lung cancer 22 | 2,798
pilocytic astrocytoma 22 | 3,086
lung carcinoma 21 | 2,844
lung adenocarcinoma 20 | 2,713
atypical teratoid / rhabdoid tumor 19 | 4,369
pediatric high grade glioma 19 | 2,712
Breast cancer 18 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
malignant mesothelioma 18 | 3,162
oligodendroglioma 17 | 2,849
interstitial cystitis 15 | 2,299
subependymal giant cell astrocytoma 15 | 2,287
diabetes mellitus 14 | 1,663
ependymoma 14 | 2,514
primitive neuroectodermal tumor 14 | 3,031
adrenocortical carcinoma 13 | 1,427
astrocytic glioma 13 | 2,241
tuberculosis 13 | 1,557
ulcerative colitis 13 | 2,087
Carcinoma 12 | 2,147
acute quadriplegic myopathy 11 | 1,157
aldosterone-producing adenoma 11 | 664
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
medulloblastoma 11 | 1,524
Asthma 10 | 349
Prostatic Neoplasms 10 | 471
adult high grade glioma 10 | 2,148
astrocytoma 10 | 1,493
cystic fibrosis 10 | 1,665
group 3 medulloblastoma 10 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
posterior fossa group A ependymoma 10 | 1,511
Colorectal Neoplasms 9 | 217
Heart disease 9 | 279
Kidney disease 9 | 396
Liver carcinoma 9 | 217
Mammary Neoplasms 9 | 410
cutaneous lupus erythematosus 9 | 1,056
nasopharyngeal carcinoma 9 | 1,056
pituitary cancer 9 | 1,972
Colonic Neoplasms 8 | 126
Lung Neoplasms 8 | 171
Lung disease 8 | 132
Multiple Sclerosis 8 | 498
Myocardial Ischemia 8 | 169
Pick disease 8 | 1,893
Rheumatoid Arthritis 8 | 1,160
Stomach Neoplasms 8 | 282
colon cancer 8 | 1,475
non-small cell lung carcinoma 8 | 413
Alzheimer's disease 7 | 644
Arthritis 7 | 248
Atherosclerosis 7 | 275
Atopic dermatitis 7 | 944
Cerebrovascular disease 7 | 231
Endometriosis 7 | 535
Hyperglycemia 7 | 120
Hypertension 7 | 287
Inflammation 7 | 109
Obesity 7 | 616
Schizophrenia 7 | 501
Waldenstrons macroglobulinemia 7 | 765
active Crohn's disease 7 | 918
atypical teratoid/rhabdoid tumor 7 | 1,095
breast carcinoma 7 | 1,614
dermatomyositis 7 | 933
gastric carcinoma 7 | 832
pancreatic cancer 7 | 2,300
Acute kidney injury 6 | 65
Bladder Neoplasm 6 | 109
Brain disease 6 | 83
Cardiomegaly 6 | 66
Diabetes Mellitus, Experimental 6 | 106
Hypertensive disease 6 | 193
Liver Cirrhosis, Experimental 6 | 108
Liver disease 6 | 219
Metabolic syndrome X 6 | 155
Multiple myeloma 6 | 1,327
Parkinson's disease 6 | 364
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group B ependymoma 6 | 1,530
spina bifida 6 | 1,064
Atrial Fibrillation 5 | 110
Brain Ischemia 5 | 87
Coronary artery disease 5 | 240
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Hypersensitivity reaction type II disease 5 | 235
Vascular disease 5 | 281
hepatocellular carcinoma 5 | 532
juvenile dermatomyositis 5 | 1,189
primary pancreatic ductal adenocarcinoma 5 | 1,271

Tissue

Digestive Tract 62 | 18,473
Endocrine System 62 | 18,512
Female tissues 62 | 18,647
Liver and Pancreas 62 | 18,136
Nervous System 62 | 18,561
Skin and soft tissues 62 | 18,115
Blood and immune system 61 | 17,995
Cardiovascular System 61 | 17,958
Male tissues 61 | 17,969
Urinary Tract 61 | 18,444
Respiratory system 60 | 17,484

Target Family

Enzyme 26 | 4,146
Non-IDG 21 | 11,971
Transcription Factor 6 | 1,400
Kinase 5 | 634
Ion Channel 4 | 341
GPCR 1 | 406

GO Process

cellular response to drug 63 | 63
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein phosphatase 1 regulatory subunit 12A PPP1R12A Tbio Enzyme -3.06798 1183.0 360
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -2.96951 933.5 1234
116 kDa U5 small nuclear ribonucleoprotein component EFTUD2 Tbio Non-IDG -1.47119 32.8 165
Tyrosine 3-monooxygenase TH Tclin Enzyme -3.46911 2047.1 1002
Interferon-inducible protein AIM2 AIM2 Tbio Non-IDG -2.26799 140.7 401
Alkaline ceramidase 2 ACER2 Tchem Enzyme -0.96283 9.78 42
cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A Tclin Enzyme -1.75798 58.1 158
Fructose-1,6-bisphosphatase 1 FBP1 Tchem Enzyme -2.04268 107.9 172
Dihydropteridine reductase QDPR Tchem Enzyme -2.29735 197.7 124
Ras-related protein Rap-2a RAP2A Tbio Enzyme -2.06251 111.8 96