Development Level

Tbio 457 | 10,625
Tdark 134 | 7,003
Tchem 74 | 1,890
Tclin 15 | 602

Collection

Eligible Kinase Proteins 12 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

preweaning lethality, complete... 40 | 633
abnormal behavior 12 | 226
decreased lean body mass 12 | 195
decreased body weight 11 | 174
decreased total body fat amoun... 11 | 186
decreased bone mineral content 10 | 157
embryonic lethality prior to t... 10 | 187
increased or absent threshold ... 10 | 128
hyperactivity 9 | 108
preweaning lethality, incomple... 8 | 260
decreased bone mineral density 7 | 126
increased circulating alkaline... 7 | 119
increased mean corpuscular hem... 7 | 93
decreased grip strength 6 | 123
hypoactivity 6 | 89
increased leukocyte cell numbe... 6 | 37
abnormal embryo size 5 | 112
decreased body length 5 | 108
decreased circulating glucose ... 5 | 121
decreased lumbar vertebrae num... 5 | 62
embryonic lethality prior to o... 5 | 148
increased circulating choleste... 5 | 53
increased grip strength 5 | 83
increased lean body mass 5 | 107
increased mean corpuscular vol... 5 | 91
increased sacral vertebrae num... 5 | 62
increased total body fat amoun... 5 | 57
prenatal lethality prior to he... 5 | 64
abnormal bone structure 4 | 131
abnormal head morphology 4 | 10
abnormal lens morphology 4 | 73
decreased basophil cell number 4 | 11
decreased circulating choleste... 4 | 85
decreased circulating serum al... 4 | 79
improved glucose tolerance 4 | 56
increased bone mineral content 4 | 92
increased circulating HDL chol... 4 | 63
increased circulating iron lev... 4 | 25
increased exploration in new e... 4 | 56
increased fasted circulating g... 4 | 68
abnormal cranium morphology 3 | 32
abnormal kidney morphology 3 | 30
abnormal limb bud morphology 3 | 15
abnormal retina morphology 3 | 100
abnormal spleen morphology 3 | 36
abnormal tail morphology 3 | 17
abnormal tail movements 3 | 12
abnormal testis morphology 3 | 30
decreased circulating triglyce... 3 | 83
decreased leukocyte cell numbe... 3 | 54
hydrops fetalis 3 | 22
impaired glucose tolerance 3 | 52
increased body weight 3 | 42
increased bone mineral density 3 | 52
increased circulating glucose ... 3 | 16
increased hematocrit 3 | 36
male infertility 3 | 62
short tibia 3 | 82
small testis 3 | 37
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal coat/ hair morphology 2 | 18
abnormal embryo turning 2 | 15
abnormal gait 2 | 51
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 14
abnormal lung morphology 2 | 15
abnormal neural tube closure 2 | 37
abnormal response to tactile s... 2 | 16
abnormal sleep behavior 2 | 63
abnormal startle reflex 2 | 14
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
decreased blood urea nitrogen ... 2 | 31
decreased circulating HDL chol... 2 | 77
decreased circulating bilirubi... 2 | 14
decreased circulating calcium ... 2 | 33
decreased circulating free fat... 2 | 39
decreased circulating total pr... 2 | 41
decreased eosinophil cell numb... 2 | 41
decreased hematocrit 2 | 25
decreased lactate dehydrogenas... 2 | 14
decreased startle reflex 2 | 48
edema 2 | 11
embryonic growth retardation 2 | 28
enlarged heart 2 | 111
hemorrhage 2 | 12
immune system phenotype 2 | 17
increased NK cell number 2 | 19
increased circulating LDL chol... 2 | 15
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased rib number 2 | 41
increased startle reflex 2 | 38
increased thermal nociceptive ... 2 | 9
limb grasping 2 | 35
vertebral fusion 2 | 23
decreased circulating magnesiu... 1 | 11

Disease

ovarian cancer 390 | 8,492
osteosarcoma 347 | 7,933
medulloblastoma, large-cell 289 | 6,234
psoriasis 256 | 6,685
glioblastoma 249 | 5,572
atypical teratoid / rhabdoid tumor 210 | 4,369
lung cancer 198 | 4,473
primitive neuroectodermal tumor 167 | 3,031
Breast cancer 159 | 3,099
malignant mesothelioma 152 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 139 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 133 | 2,988
group 3 medulloblastoma 132 | 2,254
pediatric high grade glioma 130 | 2,712
oligodendroglioma 129 | 2,849
non-small cell lung cancer 124 | 2,798
invasive ductal carcinoma 122 | 2,950
Carcinoma 115 | 2,147
Pick disease 115 | 1,893
ependymoma 114 | 2,514
posterior fossa group B ependymoma 107 | 1,530
lung adenocarcinoma 101 | 2,714
Cancer 100 | 2,346
astrocytic glioma 95 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 95 | 2,956
pilocytic astrocytoma 95 | 3,086
subependymal giant cell astrocytoma 88 | 2,287
adrenocortical carcinoma 85 | 1,427
lung carcinoma 84 | 2,844
adult high grade glioma 81 | 2,148
pancreatic cancer 81 | 2,300
group 4 medulloblastoma 77 | 1,875
ductal carcinoma in situ 76 | 1,745
colon cancer 73 | 1,475
breast carcinoma 72 | 1,614
ulcerative colitis 68 | 2,087
interstitial cystitis 67 | 2,299
sonic hedgehog group medulloblastoma 67 | 1,482
medulloblastoma 66 | 1,524
posterior fossa group A ependymoma 66 | 1,511
astrocytoma 64 | 1,493
atypical teratoid/rhabdoid tumor 58 | 1,095
nasopharyngeal carcinoma 58 | 1,056
pituitary cancer 58 | 1,972
Multiple myeloma 56 | 1,328
diabetes mellitus 55 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 53 | 1,795
tuberculosis 53 | 1,563
Intellectual disability 52 | 573
acute quadriplegic myopathy 52 | 1,157
Rheumatoid Arthritis 48 | 1,171
spina bifida 45 | 1,064
chronic rhinosinusitis 43 | 512
Atopic dermatitis 42 | 944
dermatomyositis 42 | 967
juvenile dermatomyositis 40 | 1,189
primary pancreatic ductal adenocarcinoma 40 | 1,271
progressive supranuclear palsy 40 | 674
tuberculosis and treatment for 6 months 39 | 686
Endometriosis 38 | 535
Waldenstrons macroglobulinemia 37 | 765
Microcephaly 34 | 149
active Crohn's disease 34 | 918
cystic fibrosis 34 | 1,670
IGA Glomerulonephritis 33 | 454
non primary Sjogren syndrome sicca 33 | 840
Ciliopathy 32 | 57
Obesity 32 | 616
Polydactyly 30 | 93
hepatocellular carcinoma 29 | 550
Neurodegenerative disease 28 | 383
acute myeloid leukemia 28 | 785
esophageal adenocarcinoma 28 | 737
primary Sjogren syndrome 28 | 789
Amyotrophic Lateral Sclerosis 27 | 432
aldosterone-producing adenoma 27 | 664
Joubert syndrome 26 | 62
Retinitis pigmentosa 26 | 156
cutaneous lupus erythematosus 26 | 1,056
Nephronophthisis 25 | 74
gastric cancer 25 | 436
pancreatic carcinoma 25 | 567
Prostatic Neoplasms 24 | 471
hereditary spastic paraplegia 23 | 313
Bardet-Biedl Syndrome 22 | 40
Mammary Neoplasms 22 | 410
Schizophrenia 22 | 503
gastric carcinoma 22 | 832
Alzheimer's disease 21 | 644
Asphyxiating thoracic dystrophy 21 | 34
fibroadenoma 21 | 557
Down syndrome 20 | 548
Parkinson's disease 18 | 364
Meckel syndrome 17 | 48
active ulcerative colitis 17 | 477
cystic fibrosis and chronic rhinosinusitis 17 | 213
non-small cell lung carcinoma 17 | 413
Fundus dystrophy 15 | 77
glioblastoma multiforme 15 | 347
Duchenne muscular dystrophy 14 | 602

Tissue

Endocrine System 671 | 18,512
Digestive Tract 670 | 18,473
Female tissues 670 | 18,647
Liver and Pancreas 670 | 18,136
Nervous System 670 | 18,561
Blood and immune system 669 | 17,995
Cardiovascular System 669 | 17,958
Male tissues 669 | 17,969
Urinary Tract 669 | 18,444
Skin and soft tissues 666 | 18,115
Respiratory system 663 | 17,484

Target Family

Non-IDG 473 | 11,969
Enzyme 108 | 4,146
Kinase 58 | 634
Transcription Factor 19 | 1,400
Transporter 8 | 473
Epigenetic 7 | 242
Ion Channel 4 | 341
GPCR 2 | 408
Nuclear Receptor 1 | 48

Compartment GO Term

Microtubule organizing center 680 | 680
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability