Development Level

Tbio 52 | 11,445
Tclin 48 | 613
Tdark 9 | 6,588
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 21 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
pallor 4 | 34
cataract 3 | 92
decreased vertical activity 3 | 208
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
embryonic growth retardation 2 | 106
increased circulating phosphat... 2 | 26
prenatal lethality prior to he... 2 | 87
abnormal allantois morphology 1 | 8
abnormal chorioallantoic fusio... 1 | 8
abnormal digit morphology 1 | 10
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal embryonic autopod pla... 1 | 2
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 5
abnormal sensory capabilities-... 1 | 8
abnormal stomach morphology 1 | 10
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total retina thickne... 1 | 17
enlarged heart atrium 1 | 4
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pale liver 1 | 6
pale yolk sac 1 | 25
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

ovarian cancer 62 | 8,520
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
Leigh disease 41 | 100
Cerebellar Ataxia 39 | 304
Multiple myeloma 39 | 1,332
osteosarcoma 37 | 7,950
Acidosis, Lactic 34 | 97
Lactic acidemia 34 | 95
Autosomal recessive predisposition 33 | 1,442
Carcinoma 32 | 11,493
Cognitive delay 32 | 608
Global developmental delay 32 | 608
Mental and motor retardation 32 | 608
Blepharoptosis 31 | 231
Mitochondrial complex I deficiency 30 | 46
Sensorineural Hearing Loss (disorder) 30 | 284
psoriasis 30 | 6,694
Epilepsy 28 | 792
Muscle hypotonia 27 | 571
Seizures 27 | 596
lung cancer 27 | 4,740
Failure to gain weight 26 | 365
Increased serum lactate 26 | 60
Nystagmus 26 | 317
Pediatric failure to thrive 26 | 365
Optic Atrophy 25 | 242
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
CSF lactate increased 24 | 33
Dystonia 24 | 164
Highly variable clinical phenotype 24 | 150
Highly variable phenotype and severity 24 | 150
Highly variable phenotype, even within families 24 | 150
Phenotypic variability 24 | 150
astrocytic glioma 24 | 2,597
Dystonic disease 23 | 106
Hyperreflexia 23 | 209
Muscle Spasticity 23 | 195
Muscle Weakness 22 | 170
Respiratory Failure 22 | 104
Strabismus 22 | 270
Developmental regression 21 | 95
Leigh syndrome 21 | 28
Loss of developmental milestones 21 | 95
Mental deterioration in childhood 21 | 95
Mitochondrial Complex 1 Deficiency 21 | 28
Neurodevelopmental regression 21 | 95
Psychomotor regression 21 | 95
Psychomotor regression beginning in infancy 21 | 95
Psychomotor regression in infants 21 | 95
Psychomotor regression, progressive 21 | 95
glioblastoma 21 | 5,792
medulloblastoma, large-cell 21 | 6,241
Hypertrophic Cardiomyopathy 20 | 117
diabetes mellitus 20 | 1,728
Impaired exercise tolerance 19 | 42
Ophthalmoplegia 19 | 106
ependymoma 19 | 4,679
Abnormal mitochondria in muscle tissue 18 | 20
Dull intelligence 18 | 645
Intellectual disability 18 | 1,016
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
NADH:Q(1) Oxidoreductase deficiency 18 | 24
Poor school performance 18 | 645
atypical teratoid / rhabdoid tumor 18 | 5,112
Retinitis Pigmentosa 17 | 226
Atrophy of cerebellum 15 | 103
Cancer 15 | 2,499
Cerebellar degeneration 15 | 103
Hypoglycemia 15 | 152
Infratentorial atrophy 15 | 103
Neurogenic Muscular Atrophy 15 | 139
Neurogenic muscle atrophy, especially in the lower limbs 15 | 139
Skeletal muscle atrophy 15 | 139
muscle degeneration 15 | 139
Babinski Reflex 14 | 100
Decreased tendon reflex 14 | 122
Dysarthria 14 | 192
Feeding difficulties in infancy 14 | 175
Infantile onset 14 | 238
Lactic acidosis 14 | 51
Liver Failure 14 | 73
Mood swings 14 | 77
X-linked dominant 14 | 57
Blind Vision 13 | 111
Blindness, Legal 13 | 110
Comatose 13 | 56
Gliosis 13 | 56
Progressive disorder 13 | 142
Schizophrenia 13 | 1,160
Vomiting 13 | 116
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
Growth delay 12 | 114
Growth failure 12 | 114
Growth retardation 12 | 115
Myopathy 12 | 185
Waldenstrons macroglobulinemia 12 | 765
oligodendroglioma 12 | 2,850

Tissue

Endocrine System 113 | 18,159
Blood and immune system 112 | 16,909
Digestive Tract 112 | 17,369
Female tissues 112 | 17,400
Male tissues 112 | 17,142
Skin and soft tissues 112 | 17,230
Urinary Tract 112 | 16,678
Liver and Pancreas 111 | 16,750
Nervous System 111 | 16,725
Cardiovascular System 110 | 15,192
Respiratory system 109 | 16,393

Target Family

Enzyme 88 | 4,145
Non-IDG 22 | 12,091
Transcription Factor 2 | 1,400
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

GO:0098803 115 | 115
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability