Development Level

Tchem 34 | 1,598
Tbio 19 | 11,445
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal gait 2 | 69
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal brain morphology 1 | 13
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal blood vessel ... 1 | 26
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
absent seminal vesicle 1 | 4
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
short tibia 1 | 97
small uterus 1 | 3
thrombocytopenia 1 | 56

Disease

Cancer 59 | 2,499
Carcinoma 50 | 11,493
ovarian cancer 50 | 8,520
glioblastoma 41 | 5,792
psoriasis 40 | 6,694
osteosarcoma 38 | 7,950
lung cancer 37 | 4,740
medulloblastoma, large-cell 31 | 6,241
ependymoma 29 | 4,679
atypical teratoid / rhabdoid tumor 28 | 5,112
ulcerative colitis 24 | 1,819
Breast cancer 23 | 3,578
lung adenocarcinoma 23 | 2,716
Kidney cancer 22 | 2,613
diabetes mellitus 22 | 1,728
lung carcinoma 22 | 2,843
Rheumatoid arthritis 21 | 1,191
group 3 medulloblastoma 21 | 4,104
non-small cell lung cancer 21 | 2,890
oligodendroglioma 21 | 2,850
Arthritis 20 | 290
Schizophrenia 20 | 1,160
pancreatic cancer 20 | 2,398
Vascular disease 19 | 319
invasive ductal carcinoma 19 | 2,951
adult high grade glioma 18 | 3,801
group 4 medulloblastoma 18 | 1,855
Obesity 17 | 678
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Astrocytoma, Pilocytic 16 | 3,081
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
Multiple myeloma 16 | 1,332
astrocytoma 16 | 1,146
juvenile dermatomyositis 16 | 1,187
pituitary cancer 16 | 1,972
Lung Neoplasms 15 | 232
astrocytic glioma 15 | 2,597
primitive neuroectodermal tumor 15 | 3,035
subependymal giant cell astrocytoma 15 | 2,287
Brain Ischemia 14 | 110
Stomach Neoplasms 14 | 300
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
interstitial cystitis 14 | 2,312
malignant mesothelioma 14 | 3,232
tuberculosis 14 | 2,010
Alzheimer's disease 13 | 658
Asthma 13 | 385
Carcinoma, Hepatocellular 13 | 228
Heart disease 13 | 306
Hyperglycemia 13 | 137
Liver carcinoma 13 | 240
Pick disease 13 | 1,894
Prostatic Neoplasms 13 | 495
cystic fibrosis 13 | 1,696
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
primary pancreatic ductal adenocarcinoma 13 | 1,109
Hypertension 12 | 396
Kidney disease 12 | 430
Liver Cirrhosis, Experimental 12 | 769
Lung disease 12 | 142
Short stature 12 | 531
Atherosclerosis 11 | 291
Neoplasm Metastasis 11 | 168
colon cancer 11 | 1,478
Acquired scoliosis 10 | 281
Atopic dermatitis 10 | 952
Autosomal recessive predisposition 10 | 1,442
Carcinoma, Squamous Cell 10 | 110
Cell Transformation, Neoplastic 10 | 97
Curvature of spine 10 | 282
Hypertensive disease 10 | 292
Inflammatory bowel disease 10 | 151
Major Depressive Disorder 10 | 301
Neoplasm Invasiveness 10 | 161
Squamous cell carcinoma 10 | 129
acute quadriplegic myopathy 10 | 1,158
dermatomyositis 10 | 966
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Anemia 9 | 365
Byzanthine arch palate 9 | 194
Diabetes Mellitus, Experimental 9 | 108
Disease Models, Animal 9 | 155
Hyperalgesia 9 | 83
Hypoplastic mandible condyle 9 | 275
Liver neoplasms 9 | 130
Mandibular hypoplasia 9 | 275
Melanoma 9 | 711
Micrognathism 9 | 275
Myocardial Ischemia 9 | 169
Orbital separation excessive 9 | 244
Parkinson's disease 9 | 392
Reperfusion Injury 9 | 86
Unipolar Depression 9 | 250
gastric carcinoma 9 | 807
Bipolar Disorder 8 | 666
periodontitis 8 | 293

Tissue

Blood and immune system 65 | 16,909
Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Male tissues 65 | 17,142
Respiratory system 65 | 16,393
Urinary Tract 65 | 16,678
Liver and Pancreas 64 | 16,750
Nervous System 64 | 16,725
Skin and soft tissues 64 | 17,230
Cardiovascular System 63 | 15,192

Target Family

Kinase 23 | 634
Non-IDG 19 | 12,091
Transcription Factor 14 | 1,400
Enzyme 9 | 4,145

WikiPathways Pathway

Oncostatin M Signaling Pathway 65 | 65
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability