Development Level

Tchem 24 | 1,598
Tclin 13 | 613
Tbio 12 | 11,445

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased heart left ventricle... 1 | 4
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 40 | 11,493
Cancer 39 | 2,499
ovarian cancer 34 | 8,520
osteosarcoma 30 | 7,950
glioblastoma 23 | 5,792
lung cancer 23 | 4,740
medulloblastoma, large-cell 19 | 6,241
psoriasis 18 | 6,694
malignant mesothelioma 17 | 3,232
Schizophrenia 16 | 1,160
diabetes mellitus 16 | 1,728
Arthritis 15 | 290
group 4 medulloblastoma 15 | 1,855
Asthma 14 | 385
atypical teratoid / rhabdoid tumor 14 | 5,112
Kidney cancer 13 | 2,613
Multiple myeloma 13 | 1,332
lung carcinoma 13 | 2,843
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
interstitial cystitis 12 | 2,312
invasive ductal carcinoma 12 | 2,951
Alzheimer's disease 11 | 658
Heart disease 11 | 306
Kidney disease 11 | 430
Stomach Neoplasms 11 | 300
Waldenstrons macroglobulinemia 11 | 765
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
Anemia 10 | 365
Breast Neoplasms 10 | 445
Lung Neoplasms 10 | 232
Mammary Neoplasms 10 | 425
Rheumatoid arthritis 10 | 1,191
astrocytoma 10 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
juvenile dermatomyositis 10 | 1,187
primary Sjogren syndrome 10 | 735
Astrocytoma, Pilocytic 9 | 3,081
Depressive disorder 9 | 409
Obesity 9 | 678
Orbital separation excessive 9 | 244
Prostatic Neoplasms 9 | 495
Short stature 9 | 531
Vascular disease 9 | 319
group 3 medulloblastoma 9 | 4,104
pancreatic cancer 9 | 2,398
pituitary cancer 9 | 1,972
Allergic hypersensitivity disease 8 | 126
Blepharoptosis 8 | 231
Carcinoma, Squamous Cell 8 | 110
Cell Transformation, Neoplastic 8 | 97
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Liver Cirrhosis, Experimental 8 | 769
Liver Neoplasms, Experimental 8 | 59
Lung disease 8 | 142
Mental and motor retardation 8 | 608
Squamous cell carcinoma 8 | 129
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
cystic fibrosis 8 | 1,696
dermatomyositis 8 | 966
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Acquired scoliosis 7 | 281
Byzanthine arch palate 7 | 194
Concave bridge of nose 7 | 195
Cryptorchidism 7 | 296
Curvature of spine 7 | 282
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Downward slant of palpebral fissure 7 | 158
Hypereosinophilic syndrome 7 | 71
Hypoplastic mandible condyle 7 | 275
Inflammatory bowel disease 7 | 151
Liver disease 7 | 237
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Multiple Sclerosis 7 | 540
Neoplastic Cell Transformation 7 | 89
Parkinson's disease 7 | 392
Reperfusion Injury 7 | 86
acute myeloid leukemia 7 | 783
ductal carcinoma in situ 7 | 1,745
oligodendroglioma 7 | 2,850
Bipolar Disorder 6 | 666
Brain Ischemia 6 | 110
Congenital Epicanthus 6 | 177
Dull intelligence 6 | 645
Eye disease 6 | 62
Hypersensitivity reaction type II disease 6 | 253
Hypertension 6 | 396
Immune system cancer 6 | 140
Pectus excavatum 6 | 100
Pick disease 6 | 1,894

Tissue

Blood and immune system 49 | 16,909
Endocrine System 49 | 18,159
Male tissues 49 | 17,142
Digestive Tract 48 | 17,369
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 20 | 12,091
Kinase 16 | 634
Enzyme 7 | 4,145
Transcription Factor 5 | 1,400
GPCR 1 | 408

WikiPathways Pathway

IL-3 Signaling Pathway 49 | 49
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability