Development Level

Tclin 141 | 613
Tchem 105 | 1,598
Tbio 28 | 11,445
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Targets) 17 | 126
Ion Channel: IDG Consortium (T... 12 | 99
GPCR: IDG Consortium (Complete... 5 | 25

IMPC Phenotype

preweaning lethality, incomple... 10 | 499
decreased vertical activity 8 | 208
abnormal behavior 7 | 298
decreased bone mineral content 7 | 151
preweaning lethality, complete... 7 | 979
decreased lean body mass 6 | 135
enlarged heart 6 | 210
hyperactivity 6 | 148
increased total body fat amoun... 6 | 134
decreased heart weight 5 | 27
abnormal behavioral response t... 4 | 66
decreased body weight 4 | 161
decreased bone mineral density 4 | 126
decreased total body fat amoun... 4 | 207
abnormal bone structure 3 | 187
abnormal epididymis morphology 3 | 42
abnormal heart morphology 3 | 162
abnormal seminal vesicle morph... 3 | 114
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 76
increased startle reflex 3 | 112
tremors 3 | 39
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased circulating alanine ... 2 | 47
decreased circulating insulin ... 2 | 76
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
female infertility 2 | 60
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
limb grasping 2 | 41
male infertility 2 | 123
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal joint morphology 1 | 23
abnormal liver morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
brachydactyly 1 | 19
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased urine magnesium leve... 1 | 3
edema 1 | 59
embryonic lethality prior to t... 1 | 278
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating lipase l... 1 | 3
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
microphthalmia 1 | 26
polycystic kidney 1 | 15
small kidney 1 | 16
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16
syndactyly 1 | 23
trunk curl 1 | 16
urinary bladder obstruction 1 | 4

Disease

Carcinoma 226 | 11,493
psoriasis 122 | 6,694
medulloblastoma, large-cell 100 | 6,241
Schizophrenia 99 | 1,160
glioblastoma 91 | 5,792
osteosarcoma 90 | 7,950
ependymoma 84 | 4,679
atypical teratoid / rhabdoid tumor 82 | 5,112
adult high grade glioma 76 | 3,801
ovarian cancer 76 | 8,520
Bipolar Disorder 73 | 666
Astrocytoma, Pilocytic 69 | 3,081
group 3 medulloblastoma 63 | 4,104
Alcoholic Intoxication, Chronic 62 | 289
primitive neuroectodermal tumor 62 | 3,035
oligodendroglioma 59 | 2,850
Depressive disorder 58 | 409
lung cancer 58 | 4,740
astrocytic glioma 57 | 2,597
Epilepsy 56 | 792
Kidney cancer 54 | 2,613
lung carcinoma 49 | 2,843
Mental Depression 48 | 333
Cancer 45 | 2,499
General anesthesia 45 | 53
Obesity 43 | 678
Major Depressive Disorder 42 | 301
Mood Disorders 42 | 184
interstitial cystitis 42 | 2,312
invasive ductal carcinoma 41 | 2,951
lung adenocarcinoma 40 | 2,716
Autistic Disorder 38 | 364
Parkinson's disease 38 | 392
Alcohol dependence 36 | 107
Autosomal recessive predisposition 36 | 1,442
diabetes mellitus 36 | 1,728
malignant mesothelioma 36 | 3,232
pituitary cancer 35 | 1,972
Breast cancer 34 | 3,578
subependymal giant cell astrocytoma 34 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
non-small cell lung cancer 32 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
Asthma 30 | 385
Hypertension 30 | 396
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
ulcerative colitis 28 | 1,819
Seizures 27 | 596
pancreatic cancer 27 | 2,398
Attention deficit hyperactivity disorder 26 | 278
Local anesthesia 26 | 40
Unipolar Depression 26 | 250
ductal carcinoma in situ 26 | 1,745
Alcoholism 25 | 45
Cocaine-Related Disorders 25 | 92
Migraine 25 | 83
Tonic-clonic epilepsy 25 | 47
colon cancer 25 | 1,478
Pick disease 24 | 1,894
tuberculosis 24 | 2,010
Allergic rhinitis 23 | 94
Anxiety 23 | 136
Substance Withdrawal Syndrome 23 | 55
breast carcinoma 23 | 1,638
Pain agnosia 22 | 104
Alzheimer's disease 21 | 658
Melanoma 20 | 711
Nicotine dependence 20 | 54
group 4 medulloblastoma 20 | 1,855
Insomnia 19 | 20
Irritable bowel syndrome 19 | 60
Panic disorder 19 | 61
cystic fibrosis 19 | 1,696
Cerebrovascular disease 18 | 238
Hypertensive disease 18 | 292
Liver Cirrhosis, Experimental 18 | 769
Migraine Prevention 18 | 23
Nasal congestion 18 | 21
Nasal discharge 18 | 24
Status Epilepticus 18 | 98
adrenocortical carcinoma 18 | 1,428
cutaneous lupus erythematosus 18 | 1,057
Cocaine Dependence 17 | 51
Hyperalgesia 17 | 83
Pain 17 | 103
Spasticity 17 | 26
Common cold 16 | 67
Constipation 16 | 181
Multiple Sclerosis 16 | 540
Toxic encephalopathy 16 | 141
Endometriosis 15 | 540
Hypertensive disorder 15 | 56
Hypotension 15 | 82
Intellectual disability 15 | 1,016
Lennox-Gastaut syndrome 15 | 34
Psychotic Disorders 15 | 151
Sedation as Adjunct to Anesthesia 15 | 15
Substance abuse 15 | 59
Vascular disease 15 | 319
astrocytoma 15 | 1,146

Tissue

Endocrine System 262 | 18,159
Nervous System 242 | 16,725
Female tissues 237 | 17,400
Digestive Tract 236 | 17,369
Skin and soft tissues 232 | 17,230
Male tissues 219 | 17,142
Blood and immune system 216 | 16,909
Liver and Pancreas 211 | 16,750
Urinary Tract 209 | 16,678
Respiratory system 198 | 16,393
Cardiovascular System 165 | 15,192

Target Family

GPCR 186 | 408
Ion Channel 64 | 344
Non-IDG 16 | 12,091
Enzyme 7 | 4,145
Nuclear Receptor 3 | 48

KEGG Pathway

Neuroactive ligand-receptor in... 276 | 276
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability