Development Level

Tbio 111 | 11,651
Tdark 45 | 6,593
Tchem 18 | 1,388
Tclin 8 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
increased or absent threshold ... 4 | 101
decreased startle reflex 3 | 75
enlarged heart 3 | 210
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal vitelline vasculature... 1 | 6
absent startle reflex 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased heart weight 1 | 27
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased cardiac stroke volum... 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased granulocyte number 1 | 1
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
mydriasis 1 | 6
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 114 | 11,493
ovarian cancer 90 | 8,520
medulloblastoma, large-cell 68 | 6,241
osteosarcoma 67 | 7,950
psoriasis 62 | 6,694
glioblastoma 57 | 5,792
atypical teratoid / rhabdoid tumor 55 | 5,112
lung cancer 51 | 4,740
ependymoma 46 | 4,679
group 3 medulloblastoma 45 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,955
Breast cancer 40 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
non-small cell lung cancer 38 | 2,890
lung carcinoma 37 | 2,843
pancreatic cancer 37 | 2,398
interstitial cystitis 34 | 2,312
lung adenocarcinoma 34 | 2,716
adult high grade glioma 33 | 3,801
malignant mesothelioma 30 | 3,232
primitive neuroectodermal tumor 29 | 3,035
invasive ductal carcinoma 27 | 2,951
oligodendroglioma 27 | 2,850
pituitary cancer 27 | 1,972
Astrocytoma, Pilocytic 26 | 3,081
Cancer 26 | 2,499
astrocytic glioma 25 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
subependymal giant cell astrocytoma 24 | 2,287
cystic fibrosis 23 | 1,696
Kidney cancer 22 | 2,613
Pick disease 21 | 1,894
colon cancer 21 | 1,478
diabetes mellitus 21 | 1,728
tuberculosis 20 | 2,010
ulcerative colitis 20 | 1,819
breast carcinoma 18 | 1,638
adrenocortical carcinoma 17 | 1,428
group 4 medulloblastoma 17 | 1,855
Schizophrenia 16 | 1,160
acute quadriplegic myopathy 15 | 1,158
ductal carcinoma in situ 15 | 1,745
primary pancreatic ductal adenocarcinoma 15 | 1,109
Melanoma 14 | 711
Multiple myeloma 14 | 1,332
active ulcerative colitis 14 | 764
esophageal adenocarcinoma 14 | 737
aldosterone-producing adenoma 13 | 665
nasopharyngeal carcinoma 13 | 1,058
pediatric high grade glioma 13 | 1,064
juvenile dermatomyositis 12 | 1,187
Gastritis 11 | 47
Liver Cirrhosis, Experimental 11 | 769
Obesity 11 | 678
Prostatic Neoplasms 11 | 495
cutaneous lupus erythematosus 11 | 1,057
Rheumatoid arthritis 10 | 1,191
non primary Sjogren syndrome sicca 10 | 891
Alzheimer's disease 9 | 658
Duchenne muscular dystrophy 9 | 601
astrocytoma 9 | 1,146
chronic rhinosinusitis 9 | 512
fibroadenoma 9 | 559
hepatocellular carcinoma 9 | 547
spina bifida 9 | 1,074
Acquired metabolic disease 8 | 336
Barrett's esophagus 8 | 182
Bipolar Disorder 8 | 666
active Crohn's disease 8 | 922
non-small cell lung carcinoma 8 | 317
progressive supranuclear palsy 8 | 676
Chemical and Drug Induced Liver Injury 7 | 195
Intellectual disability 7 | 1,016
Multiple Sclerosis 7 | 540
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric carcinoma 7 | 807
medulloblastoma 7 | 720
posterior fossa group A ependymoma 7 | 468
Asthma 6 | 385
Down syndrome 6 | 499
Endometriosis 6 | 540
Epilepsy 6 | 792
Seizures 6 | 596
dermatomyositis 6 | 966
gastric cancer 6 | 459
mucosa-associated lymphoid tissue lymphoma 6 | 484
nephrosclerosis 6 | 333
pancreatic carcinoma 6 | 562
Autistic Disorder 5 | 364
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Chronic obstructive pulmonary disease 5 | 184
Hypertension 5 | 396
Mammary Neoplasms 5 | 425
Skin cancer 5 | 469
head and neck cancer 5 | 271
primary Sjogren syndrome 5 | 735

Tissue

Digestive Tract 179 | 17,369
Female tissues 178 | 17,400
Endocrine System 176 | 18,159
Blood and immune system 175 | 16,909
Nervous System 175 | 16,725
Skin and soft tissues 175 | 17,230
Urinary Tract 175 | 16,678
Liver and Pancreas 174 | 16,750
Male tissues 173 | 17,142
Respiratory system 172 | 16,393
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 47 | 4,145
GPCR 6 | 408
Kinase 4 | 634
Transporter 4 | 473
Transcription Factor 3 | 1,400
Ion Channel 1 | 344

Jensen-KB Tissue

Stomach 182 | 182
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase ST8SIA1 Tbio Enzyme -1.52525 35.4 40
General transcription factor IIF subunit 1 GTF2F1 Tbio Non-IDG -1.59873 42.5 176
ER lumen protein-retaining receptor 3 KDELR3 Tdark Non-IDG 0.40 0.12 65
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.90485 75.1 549
Centromere protein W CENPW Tbio Non-IDG -1.12039 16.1 51
HLA class II histocompatibility antigen, DR beta 5 chain HLA-DRB5 Tbio Non-IDG -2.63614 462.9 97
Isochorismatase domain-containing protein 2 ISOC2 Tbio Enzyme -0.15970 1.50 70
Torsin-3A TOR3A Tbio Non-IDG -2.11529 122.6 101
Protein phosphatase 1B PPM1B Tchem Enzyme -1.55136 36.3 200