Development Level

Tbio 40 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hydrops fetalis 1 | 1
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating insulin ... 1 | 3
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74

Disease

Carcinoma 38 | 11,493
osteosarcoma 27 | 7,950
ovarian cancer 26 | 8,520
psoriasis 23 | 6,694
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 16 | 4,104
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
lung cancer 14 | 4,740
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
lung adenocarcinoma 12 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
ductal carcinoma in situ 8 | 1,745
Cancer 7 | 2,499
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
group 4 medulloblastoma 6 | 1,855
primary pancreatic ductal adenocarcinoma 6 | 1,109
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Multiple myeloma 5 | 1,332
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
esophageal adenocarcinoma 5 | 737
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
fibroadenoma 4 | 559
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 952
Intellectual disability 3 | 1,016
Neurodegenerative disease 3 | 414
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Asthma 2 | 385
Atherosclerosis 2 | 291
Breast Neoplasms 2 | 445
Cleft Palate 2 | 271
Colorectal adenoma 2 | 15
Composite lymphoma 2 | 3
Congenital diaphragmatic hernia 2 | 67
Congenital hypoplasia of penis 2 | 176
Craniofacial Abnormalities 2 | 151
Cryptorchidism 2 | 296
Dental caries 2 | 164
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Exudative vitreoretinopathy 2 | 15
Hypersensitivity reaction type II disease 2 | 253
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Mammary Neoplasms 2 | 425
Multiple Sclerosis 2 | 540
Neuropathy 2 | 261
Norrie disease 2 | 14
Polycystic ovary syndrome 2 | 360
Polydactyly 2 | 107
Prostatic Neoplasms 2 | 495
Retinopathy of prematurity 2 | 22
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
fascioscapulohumeral muscular dystrophy 2 | 100
glioblastoma multiforme 2 | 142
hearing impairment 2 | 199
interstitial lung disease 2 | 298
mucosa-associated lymphoid tissue lymphoma 2 | 484
posterior fossa group A ependymoma 2 | 468
progressive supranuclear palsy 2 | 676
Iron metabolism disease 1 | 20
Poor speech 1 | 37

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Skin and soft tissues 47 | 17,230
Nervous System 46 | 16,725
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192
Respiratory system 44 | 16,393

Target Family

Non-IDG 26 | 12,091
Enzyme 10 | 4,145
GPCR 7 | 408
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

Jensen-KB Tissue

Gastroesophageal cancer cell 48 | 48
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Frizzled-10 FZD10 Tbio GPCR -1.39120 24.2 172
FYVE, RhoGEF and PH domain-containing protein 5 FGD5 Tbio Non-IDG -0.79659 8.16 64
Zinc finger protein 517 ZNF517 Tdark Transcription Factor 0.39 0.10 68
Volume-regulated anion channel subunit LRRC8E LRRC8E Tdark Non-IDG -0.53782 2.37 37
Methionine-R-sulfoxide reductase B3 MSRB3 Tbio Enzyme -1.27275 18.8 55
Cytosolic carboxypeptidase 1 AGTPBP1 Tbio Enzyme -1.64119 47.2 230
Extended synaptotagmin-2 ESYT2 Tbio Non-IDG -1.20659 15.4 56
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Growth factor receptor-bound protein 7 GRB7 Tbio Non-IDG -2.09785 134.5 252
Probable Xaa-Pro aminopeptidase 3 XPNPEP3 Tbio Enzyme -1.25552 17.3 113