Development Level

Tbio 7,793 | 10,625
Tdark 3,364 | 7,003
Tchem 1,345 | 1,890
Tclin 334 | 602

Collection

Kinase: IDG Consortium (Targets) 93 | 125
Ion Channel: IDG Consortium (Targets) 41 | 102
Kinase: IDG Consortium (Complete/Control) 31 | 37
GPCR: IDG Consortium (Targets) 29 | 127
GPCR: IDG Consortium (Complete/Control) 9 | 26

IMPC Phenotype

preweaning lethality, complete... 571 | 633
preweaning lethality, incomple... 212 | 260
abnormal behavior 185 | 226
embryonic lethality prior to t... 173 | 187
decreased total body fat amoun... 157 | 186
decreased lean body mass 156 | 195
decreased body weight 147 | 174
embryonic lethality prior to o... 143 | 148
decreased bone mineral content 123 | 157
decreased bone mineral density 101 | 126
abnormal embryo size 100 | 112
abnormal bone structure 99 | 131
increased circulating alkaline... 99 | 119
increased or absent threshold ... 96 | 128
decreased circulating glucose ... 92 | 121
decreased body length 91 | 108
decreased grip strength 88 | 123
hyperactivity 85 | 108
abnormal retina morphology 82 | 100
increased mean corpuscular hem... 82 | 93
increased lean body mass 81 | 107
enlarged heart 78 | 111
increased bone mineral content 78 | 92
increased mean corpuscular vol... 77 | 91
hypoactivity 72 | 89
decreased circulating choleste... 70 | 85
short tibia 69 | 82
decreased circulating serum al... 67 | 79
decreased circulating HDL chol... 65 | 77
decreased circulating triglyce... 63 | 83
increased grip strength 63 | 83
prenatal lethality prior to he... 58 | 64
abnormal lens morphology 57 | 73
increased fasted circulating g... 55 | 68
decreased lumbar vertebrae num... 52 | 62
increased sacral vertebrae num... 52 | 62
abnormal retinal pigmentation 50 | 61
decreased circulating insulin ... 50 | 75
decreased rib number 49 | 59
increased circulating sodium l... 49 | 71
male infertility 49 | 62
abnormal sleep behavior 46 | 63
abnormal coat-hair pigmentatio... 45 | 54
decreased leukocyte cell numbe... 45 | 54
decreased mean corpuscular vol... 45 | 50
abnormal bone mineralization 44 | 55
decreased hemoglobin content 44 | 53
decreased prepulse inhibition 42 | 52
increased bone mineral density 42 | 52
increased circulating HDL chol... 42 | 63
increased total body fat amoun... 42 | 57
impaired glucose tolerance 41 | 52
decreased caudal vertebrae num... 40 | 49
increased circulating choleste... 40 | 53
decreased circulating alanine ... 39 | 53
decreased erythrocyte cell num... 39 | 43
decreased fasted circulating g... 38 | 49
improved glucose tolerance 38 | 56
abnormal gait 37 | 51
abnormal behavioral response t... 36 | 52
decreased circulating total pr... 36 | 41
decreased startle reflex 36 | 48
increased exploration in new e... 36 | 56
thrombocytopenia 36 | 46
abnormal neural tube closure 35 | 37
decreased eosinophil cell numb... 34 | 41
decreased heart weight 33 | 44
increased blood urea nitrogen ... 33 | 44
increased body weight 33 | 42
abnormal heart morphology 32 | 51
decreased circulating LDL chol... 32 | 37
increased hemoglobin content 32 | 45
increased rib number 32 | 41
abnormal seminal vesicle morph... 31 | 47
decreased circulating free fat... 31 | 39
abnormal cranium morphology 30 | 32
abnormal eye morphology 30 | 38
decreased circulating alkaline... 30 | 41
decreased neutrophil cell numb... 30 | 37
increased hematocrit 30 | 36
decreased circulating fructosa... 29 | 31
decreased mean corpuscular hem... 29 | 34
increased startle reflex 29 | 38
decreased circulating calcium ... 28 | 33
tremors 28 | 34
decreased T cell number 27 | 31
decreased circulating creatini... 27 | 31
increased circulating chloride... 27 | 43
increased heart weight 27 | 37
increased leukocyte cell numbe... 27 | 37
small testis 27 | 37
cardiovascular system phenotyp... 26 | 35
abnormal spleen morphology 25 | 36
increased circulating iron lev... 25 | 25
increased circulating potassiu... 25 | 31
decreased B cell number 24 | 30
embryonic growth retardation 24 | 28
limb grasping 24 | 35
decreased circulating aspartat... 23 | 27
decreased circulating chloride... 23 | 32

Disease

ovarian cancer 7,362 | 8,491
osteosarcoma 6,499 | 7,933
medulloblastoma, large-cell 4,883 | 6,234
psoriasis 4,499 | 6,685
glioblastoma 4,484 | 5,572
lung cancer 3,833 | 4,473
atypical teratoid / rhabdoid tumor 3,464 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 2,780 | 3,289
malignant mesothelioma 2,646 | 3,163
Breast cancer 2,591 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 2,527 | 2,956
invasive ductal carcinoma 2,525 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 2,512 | 2,988
primitive neuroectodermal tumor 2,327 | 3,031
pilocytic astrocytoma 2,313 | 3,086
non-small cell lung cancer 2,259 | 2,798
oligodendroglioma 2,214 | 2,849
lung carcinoma 2,173 | 2,844
pediatric high grade glioma 2,114 | 2,712
lung adenocarcinoma 2,102 | 2,714
ependymoma 2,062 | 2,514
subependymal giant cell astrocytoma 1,904 | 2,287
pancreatic cancer 1,870 | 2,300
group 3 medulloblastoma 1,809 | 2,254
astrocytic glioma 1,786 | 2,241
interstitial cystitis 1,752 | 2,299
Cancer 1,699 | 2,346
ulcerative colitis 1,674 | 2,087
Pick disease 1,628 | 1,893
adult high grade glioma 1,595 | 2,148
group 4 medulloblastoma 1,589 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,582 | 1,795
pituitary cancer 1,535 | 1,972
Carcinoma 1,473 | 2,147
ductal carcinoma in situ 1,433 | 1,745
breast carcinoma 1,321 | 1,614
cystic fibrosis 1,306 | 1,670
tuberculosis 1,304 | 1,563
Multiple myeloma 1,287 | 1,327
astrocytoma 1,274 | 1,493
adrenocortical carcinoma 1,197 | 1,427
medulloblastoma 1,174 | 1,524
posterior fossa group B ependymoma 1,174 | 1,530
colon cancer 1,169 | 1,475
sonic hedgehog group medulloblastoma 1,164 | 1,482
primary pancreatic ductal adenocarcinoma 1,151 | 1,271
juvenile dermatomyositis 1,113 | 1,189
posterior fossa group A ependymoma 1,091 | 1,511
diabetes mellitus 1,082 | 1,663
acute quadriplegic myopathy 1,068 | 1,157
Rheumatoid Arthritis 954 | 1,170
spina bifida 898 | 1,064
dermatomyositis 892 | 966
atypical teratoid/rhabdoid tumor 840 | 1,095
cutaneous lupus erythematosus 796 | 1,056
nasopharyngeal carcinoma 766 | 1,056
gastric carcinoma 731 | 832
Waldenstrons macroglobulinemia 728 | 764
acute myeloid leukemia 723 | 785
active Crohn's disease 714 | 918
primary Sjogren syndrome 658 | 788
non primary Sjogren syndrome sicca 652 | 840
tuberculosis and treatment for 6 months 642 | 686
Atopic dermatitis 639 | 944
progressive supranuclear palsy 595 | 674
esophageal adenocarcinoma 587 | 737
aldosterone-producing adenoma 583 | 664
Duchenne muscular dystrophy 544 | 602
Alzheimer's disease 492 | 644
hepatocellular carcinoma 492 | 550
pancreatic carcinoma 492 | 567
autosomal dominant Emery-Dreifuss muscular dystrophy 466 | 499
Down syndrome 462 | 548
Intellectual disability 460 | 573
fibroadenoma 434 | 557
Obesity 407 | 616
IGA Glomerulonephritis 386 | 454
chronic rhinosinusitis 386 | 512
Prostatic Neoplasms 381 | 471
gastric cancer 379 | 436
Endometriosis 374 | 535
Amyotrophic Lateral Sclerosis 369 | 432
active ulcerative colitis 359 | 477
mucosa-associated lymphoid tissue lymphoma 356 | 480
Neurodegenerative disease 324 | 383
Mammary Neoplasms 323 | 410
Schizophrenia 318 | 503
inflammatory breast cancer 307 | 404
Multiple Sclerosis 306 | 498
hereditary spastic paraplegia 300 | 313
tuberculosis and treatment for 3 months 283 | 327
sarcoidosis 282 | 368
glioblastoma multiforme 270 | 347
non-small cell lung carcinoma 270 | 413
urothelial carcinoma 261 | 318
Polycystic Ovary Syndrome 252 | 334
interstitial lung disease 250 | 292
Kidney disease 246 | 397
Parkinson's disease 246 | 364
nephrosclerosis 241 | 329

Tissue

Endocrine System 12,836 | 18,511
Female tissues 12,833 | 18,646
Nervous System 12,833 | 18,560
Urinary Tract 12,832 | 18,443
Digestive Tract 12,831 | 18,472
Liver and Pancreas 12,830 | 18,135
Male tissues 12,829 | 17,968
Skin and soft tissues 12,826 | 18,114
Cardiovascular System 12,822 | 17,957
Blood and immune system 12,819 | 17,994
Respiratory system 12,819 | 17,483

Target Family

Non-IDG 7,408 | 11,969
Enzyme 3,155 | 4,146
Transcription Factor 947 | 1,400
Kinase 514 | 634
Transporter 288 | 473
Epigenetic 216 | 242
Ion Channel 127 | 341
GPCR 113 | 408
Nuclear Receptor 34 | 48
TF/Epigenetic 31 | 38
oGPCR 3 | 421

HPA RNA Tissue

thyroid gland 12,836 | 12,836
testis 14,882 | 14,882
gallbladder 13,733 | 13,733
fallopian tube 13,708 | 13,708
lung 13,653 | 13,653
prostate 13,628 | 13,628
cerebral cortex 13,579 | 13,579
colon 13,523 | 13,523
urinary bladder 13,516 | 13,516
stomach 13,507 | 13,507
small intestine 13,471 | 13,471
appendix 13,437 | 13,437
endometrium 13,367 | 13,367
rectum 13,362 | 13,362
esophagus 13,354 | 13,354
kidney 13,341 | 13,341
adrenal gland 13,296 | 13,296
duodenum 13,296 | 13,296
smooth muscle 13,192 | 13,192
tonsil 13,066 | 13,066
placenta 13,010 | 13,010
spleen 12,999 | 12,999
adipose tissue 12,955 | 12,955
skin 12,911 | 12,911
salivary gland 12,839 | 12,839
lymph node 12,767 | 12,767
heart muscle 12,601 | 12,601
ovary 12,538 | 12,538
liver 12,082 | 12,082
pancreas 11,994 | 11,994
bone marrow 11,255 | 11,255
skeletal muscle 11,029 | 11,029

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability