Development Level

Tbio 30 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 31
embryonic growth retardation 1 | 106
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87

Disease

group 3 medulloblastoma 25 | 4,104
ovarian cancer 25 | 8,520
Carcinoma 24 | 11,493
non-small cell lung cancer 24 | 2,890
lung cancer 23 | 4,740
medulloblastoma, large-cell 22 | 6,241
malignant mesothelioma 20 | 3,232
psoriasis 20 | 6,694
adrenocortical carcinoma 17 | 1,428
osteosarcoma 17 | 7,950
glioblastoma 16 | 5,792
primitive neuroectodermal tumor 16 | 3,035
atypical teratoid / rhabdoid tumor 15 | 5,112
Breast cancer 14 | 3,578
lung adenocarcinoma 13 | 2,716
Cancer 12 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 10 | 2,951
adult high grade glioma 9 | 3,801
nasopharyngeal carcinoma 9 | 1,058
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
Autosomal recessive predisposition 7 | 1,442
Endometriosis 7 | 540
pediatric high grade glioma 7 | 1,064
Meier-Gorlin syndrome 6 | 10
ependymoma 6 | 4,679
Atopic dermatitis 5 | 952
EAR, PATELLA, SHORT STATURE SYNDROME 5 | 7
Fetal Growth Retardation 5 | 189
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Seckel syndrome 5 | 34
Small head 5 | 374
Waldenstrons macroglobulinemia 5 | 765
Birth length less than 3rd percentile 4 | 6
Congenital small ears 4 | 48
Cryptorchidism 4 | 296
Delayed bone age 4 | 136
Failure to gain weight 4 | 365
Feeding difficulties 4 | 127
Isolated growth hormone deficiency 4 | 30
Multiple myeloma 4 | 1,332
Pediatric failure to thrive 4 | 365
Slender, gracile long tubular bones 4 | 21
breast carcinoma 4 | 1,638
oligodendroglioma 4 | 2,850
tuberculosis 4 | 2,010
Cognitive delay 3 | 608
Congenital hypoplasia of breast 3 | 25
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Dull intelligence 3 | 645
Gastroesophageal reflux disease 3 | 110
Global developmental delay 3 | 608
Heartburn 3 | 78
Hypertrophy of clitoris 3 | 40
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypotrophic maxilla 3 | 66
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Microcephaly 3 | 166
Micrognathism 3 | 275
Microstomia 3 | 78
Poor school performance 3 | 645
Retrusion of upper jaw bones 3 | 66
Rothmund-Thomson syndrome 3 | 19
Abnormality of metabolism/homeostasis 2 | 134
Astrocytoma, Pilocytic 2 | 3,081
Byzanthine arch palate 2 | 194
Congenital deafness 2 | 185
Deafness 2 | 198
Epilepsy 2 | 792
Genu varum 2 | 29
Hearing Loss, Partial 2 | 185
Malignant tumor of ovary 2 | 25
Patella aplasia-hypoplasia 2 | 12
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Recurrent respiratory infections 2 | 141
Seizures 2 | 596
Strabismus 2 | 270
Triangular face 2 | 58
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pancreatic cancer 2 | 2,398
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Digestive Tract 35 | 17,369
Nervous System 35 | 16,725
Respiratory system 35 | 16,393

Target Family

Non-IDG 24 | 12,091
Enzyme 11 | 4,145
Kinase 1 | 634

GO Process

DNA replication initiation 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA replication licensing factor MCM7 MCM7 Tbio Non-IDG -2.60651 387.2 575
DNA replication licensing factor MCM4 MCM4 Tbio Non-IDG -1.94022 86.8 319
Replication protein A 30 kDa subunit RPA4 Tbio Non-IDG -1.35379 22.3 130
DNA polymerase epsilon subunit 3 POLE3 Tbio Enzyme -0.78662 5.86 154
DNA polymerase epsilon subunit 4 POLE4 Tdark Enzyme -0.42363 2.18 40
Protein MCM10 homolog MCM10 Tbio Non-IDG -1.66398 55.1 93